Clinical trials: Neonatal Morbidity and Mortality
Perinatal Mortality, Stillbirth
Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality
The purpose of this study is to determine whether a daily prenatal supplement of iron plus folic acid or a daily prenatal supplement with multiple vitamins and minerals given to women from their first prenatal visit through…
- Conditions
- Perinatal Mortality, Stillbirth, Neonatal Mortality
- Trial name
- NCT00133744
- Testing
- folic acid, folic acid plus iron, supplements with multiple vitamins and minerals
- Where
- 5 sites in China
- Volunteers
- 18,962 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Perinatal Morbidity, Morbidity;Perinatal
Multicentric Retrospective Study of Perinatal Mortality
Background: Perinatal mortality ranges mortality from 22 gestational weeks up to the first 7 days of life and extended mortality goes up to 28 days of life.
- Conditions
- Perinatal Morbidity, Morbidity;Perinatal, Stillbirth, ICD
- Trial name
- PM-PHD-NTM (NCT05491772)
- Where
- Spain
- Volunteers
- 468 people
- Sponsor
- Corporacion Parc Tauli
Infant, Premature, Diseases, Perinatal Morbidity
Prognosis of Extremely Premature Birth
Pregnant women at risk of giving birth before 28 weeks' gestational age will be enrolled. Fetal circulation will be studied and blood for inflammatory parameters will be collected.
- Conditions
- Infant, Premature, Diseases, Perinatal Morbidity, Development, Problem;Growth
- Trial name
- BabyPEP (NCT01150396)
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- University of Bergen
Morality, Morbidity;Newborn
Comparison of Care Practices, Mortality and Morbidity of Very Preterm Infants Between Two Tertiary Centers in Northwest and South of China
Care practices, mortality and morbidity of very premature infants from two different tertiary centers were collected and compared, in order to discover areas for improvement where these two newborn centers can learn from each…
- Conditions
- Morality, Morbidity;Newborn, Very Preterm Maturity of Infant
- Trial name
- NCT05116670
- Where
- China
- Volunteers
- 807 people
- Sponsor
- Nanjing Medical University
Maternal Morbidity and Mortality, Stillbirth and Neonatal Mortality
Emergency Obstetric and Neonatal Care: The EmONC Trial
The objective of this cluster randomized controlled trial is to reduce maternal and neonatal mortality by increasing access to and improving the quality of obstetric and neonatal care for pregnant women in study clusters.
- Trial name
- EmONC (NCT01073488)
- Testing
- Community Mobilization, HBLSS and facility improvement
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 267,181 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Pulmonary Hypertension, Sickle Cell Anemia
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
The purpose of this study is to determine how often people with sickle cell anemia develop pulmonary hypertension a serious disease in which blood pressure in the artery to the lungs is elevated.
- Conditions
- Pulmonary Hypertension, Sickle Cell Anemia, Sickle Cell Disease
- Trial name
- NCT00011648
- Where
- 2 sites in United States
- Volunteers
- 986 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Preterm Birth Complication, Neonatal Morbidity and Mortality
Delayed Versus Immediate Cord Clamping in Preterm Birth
The goal of this study is to evaluate whether delayed cord clamping improves early neonatal outcomes compared with immediate clamping in preterm birth.
- Conditions
- Preterm Birth Complication, Neonatal Morbidity and Mortality, Cord Clamping, Delayed Cord Clamping
- Trial name
- PREM-CORD (NCT07699666)
- Testing
- Delayed Umbilical Cord Clamping, Immediate Umbilical Cord Clamping
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- Faculty of Medicine of Tunis
Cardiac Surgery in Neonates
Cardiac Surgery for Babies Less Than 5 kg:Risk Factors for Morbidity and Mortality
Cardiac surgery in babies less than 6 kg of weight is a complex and high-risk procedure. Despite advances in medical technology, mortality and morbidity rates remain high.
- Trial name
- NCT05891405
- Testing
- Cardiac surgery
- Volunteers
- 100 people
- Sponsor
- Sohag University
Low Birth Weight Baby, Small for Gestational Age (SGA)
Biological Impacts of Rising Temperatures on Maternal, Fetal, and Newborn Health: A Cohort Study (BIRTH Cohort)
The goal of this study is to learn how being exposed to high environmental temperatures during pregnancy affects the health of pregnant women and their babies.
- Conditions
- Low Birth Weight Baby, Small for Gestational Age (SGA), Preterm Birth, Pregnancy Complications
- Trial name
- BIRTH (NCT06957769)
- Testing
- heat stress
- Where
- 3 sites in Pakistan
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Infectious Disease, Neoplasms
AnovaOS Network Powered Patient Registry
The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and…
- Conditions
- Infectious Disease, Neoplasms, Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89), Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- Trial name
- NCT05013944
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Anova Enterprises, Inc
Preterm Birth, Low Birth Weight
Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns
This study focuses on understanding the conditions that affect newborn health and survival from pregnancy to the first weeks of life at the Isidro Ayora Hospital.
- Conditions
- Preterm Birth, Low Birth Weight, Intrauterine Growth Restriction (IUGR), Perinatal Asphyxia
- Trial name
- UCE (NCT06653374)
- Testing
- Infant, Premature
- Where
- Ecuador
- Volunteers
- 26,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Congenital Heart Defect
Cardiopediatric Home Monitoring Tool
We hypothesize that a home monitoring program combined with routine postoperative care significantly reduces morbidity and mortality after neonatal and pediatric cardiac surgery.
- Trial name
- OSCAR (NCT06741189)
- Testing
- Home monitoring, usual medical monitoring
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Nantes University Hospital
Morbidity;Infant
Survival and nEonatal outComes of veRy Low Birth wEight Infants in Türkiye: Turkish Neonatal Society SECRETS-TR Study
The aim of this multi-center study was to evaluate the mortality rate and early neonatal outcomes of very low birth weight (VLBW) infants hospitalized in neonatal intensive care units (NICUs) in Türkiye.
- Trial name
- TNS-SECRETS (NCT06543524)
- Testing
- Care of premature infants
- Where
- Turkey (Türkiye)
- Volunteers
- 3,150 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
covid19 Infection, Pregnancy Complications
Covid-19 in Pregnancy: a French Population-based Cohort of Women and Newborns
The purpose of this study is to characterize the incidence and clinical features of the maternal COVID 19 infection, as well as the associated morbidity of the mother and the child, in the French context
- Conditions
- covid19 Infection, Pregnancy Complications, Neonatal Complications
- Trial name
- Coropreg (NCT04463758)
- Testing
- An auto-questionnaire comprising three psychometric scales
- Where
- France
- Volunteers
- 6,015 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypothermia, Morbidity
Perinatal Hypothermia, Risk Factors and Long-Term Consequences in Guinea-Bissau, Westafrica
Low body temperature (hypothermia (HT)) at birth contributes to infant mortality in low-income countries. A study from Guinéa-Bissau indicates that HT results in an increased mortality rate, which persist at least two months…
- Conditions
- Hypothermia, Morbidity, Mortality
- Trial name
- NCT00429000
- Testing
- thermospot
- Where
- Guinea-Bissau
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Omphalitis, Infection
Impact of Umbilical Cord Cleansing With 4.0% Chlorhexidine on Neonatal Mortality
A community based trial that seeks to address the effect of umbilical cord cleansing using 4.0% chlorhexidine cleansing solution
- Trial name
- CHX (NCT00434408)
- Testing
- chx once, CHX x 7 days, dry cord care
- Where
- Bangladesh
- Volunteers
- 28,797 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Sickle Cell Disease, Pain Crisis Recurrent
Effectiveness of Laying-on-of-hands for Sickle Cell Disease
The objective of this study is to evaluate the effectiveness of 1-year administration of laying-on-of-hands on the morbidity and mortality of patients with sickle cell disease in Africa.
- Conditions
- Sickle Cell Disease, Pain Crisis Recurrent, Anemia, Infection
- Trial name
- NCT01518218
- Testing
- laying-on-of-hands
- Where
- Democratic Republic of the Congo
- Volunteers
- 40 people
- Sponsor
- MOA Health Science Foundation
Thoracic Aorta Dilatation, Marfan Syndrome
Thoracic Aortic Dilatation Syndromes
Aortic dilatation syndromes are comprised by a group of different syndromes, of which Marfan syndrome is the best described. Many of the aorta dilatation associated syndromes are heritable connective tissue disorders but some…
- Trial name
- NCT02111668
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Previable Labour With Intact Membranes
A Combination of Antibiotics to Decrease Neonatal Morbidity and Mortality for Previable Threatened Labor
The purpose of this study is to determine whether a combination of antibiotics (cephalosporin 3rd generation, clarithromycin, metronidazole) are effective to prolong pregnancies complicated with previable threatened labour with…
- Trial name
- ECHEC-MAT (NCT06572761)
- Testing
- Combination of antibiotics, Emergency cerclage, Vaginal progesterone
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Premature Birth
Assessment of the Impact of the Return Home of Premature Newborns Less Than 2 Kilos Morbidity/Mortality
The aim of this study is to evaluate the impact of discharge from hospital with a weight of less than 2 kilos. To do this, the investigator will look at the short-term and long-term outcome of newborns weighing less than 2 kilos…
- Trial name
- Petit-Poids (NCT06224764)
- Testing
- Mother and Father questionnaires
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hôpital NOVO