Clinical trials: Neonatal Outcome
Anesthesia; Adverse Effect, Newborn Morbidity
Does the Mode of Anesthesia Affect the Feto-maternal Outcome in Category-1 Caesarean Section
Spinal anesthesia (SA) has become the standard technique in elective cesarean section (CS) as it results in less maternal and neonatal morbidity than general anesthesia (GA) (Grade-A recommendation, NICE).
- Trial name
- NCT04634981
- Testing
- anesthesia of emergency cesarean section
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Benha University
Exocrine Pancreatic Insufficiency, Cystic Fibrosis
RESULT: Reliable, Emergent Solution Using Liprotamase Treatment
Liprotamase powder is a non-porcine, soluble and stable mixture of biotechnology-derived lipase, protease, and amylase digestive enzymes.
- Trial name
- NCT03051490
- Testing
- Liprotamase, porcine PERT
- Where
- 50 sites in United States, Hungary and 5 more
- Volunteers
- 140 people
- Sponsor
- Anthera Pharmaceuticals
Low Back Pain, Flatfoot
The Outcome Effect of Shoe Lift for Individuals With Low Back Pain and Pronated Foot Due to Anatomical Leg Length Discrepancy
People with anatomical leg length discrepancy (LLD) commonly presented excessive subtalar pronation of the long leg compared to their short leg in order to equalize leg length.
- Conditions
- Low Back Pain, Flatfoot, Leg Length Inequality
- Trial name
- NCT01187693
- Testing
- shoe lift
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Foot Injury, Foot Deformity
Comparing Clinical Outcomes Using Two Insole Manufacture Techniques
The main purpose of this study is to find out if scanning the foot using a 3D scanner influences the effectiveness of custom made insoles, compared to the more traditional approach of taking a foam-box impression cast of the…
- Conditions
- Foot Injury, Foot Deformity, Foot Sprain, Feet, Flat
- Trial name
- NCT05444192
- Testing
- CAD/CAM insoles
- Where
- United Kingdom
- Volunteers
- 114 people
- Sponsor
- NHS Greater Glasgow and Clyde
Labor, Premature
Tocolytics Trial: Intravenous (IV) Magnesium Versus Oral Nifedpine in Fetal Fibronectin (FFN) Postive Population
In women with singleton gestations, to contemporarily assess the efficacy of oral nifedipine versus intravenous magnesium sulfate in the acute management of preterm labor in terms of defined early and late neonatal measures
- Trial name
- NCT00641784
- Testing
- Magnesium, Nifedlipine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- MemorialCare
Charcot Marie Tooth Disease, Inherited Peripheral Neuropathy
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)
The purpose of this research study is to create and validate two patient reported outcome (PRO) questionnaires. PRO questionnaires ask questions that help to measure disability in patients with inherited neuropathies.
- Trial name
- DSI and HMSN (NCT02194010)
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 563 people
- Sponsor
- University of Iowa
Congenital Heart Disease, Pulmonary Valve Stenoses
Outcome of Balloon Pulmonary Valvuloplasty in Patients With Congenital Pulmonary Stenosis in Terms of Reverse Right Ventricular Remodelling and Functional Exercise Capacity
A prospective of 30 patients with symptomatic severe congenital valvular pulmonary stenosis who are indicated for percutaneous balloon pulmonary valvuloplasty . the aim is to 1.
- Trial name
- NCT05828524
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Atopic Dermatitis, Eczema
Eczema Reminder and Accountability Program
Eczema is a chronic disease that requires long term and extensive treatment. However patient adherence to the treatment plans provided to them by their healthcare providers is poor.
- Trial name
- ERAP (NCT03735459)
- Testing
- Patient reminders and accountability questionnaires
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- McMaster University
Infant, Premature, Diseases, Perinatal Morbidity
Prognosis of Extremely Premature Birth
Pregnant women at risk of giving birth before 28 weeks' gestational age will be enrolled. Fetal circulation will be studied and blood for inflammatory parameters will be collected.
- Conditions
- Infant, Premature, Diseases, Perinatal Morbidity, Development, Problem;Growth
- Trial name
- BabyPEP (NCT01150396)
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- University of Bergen
Umbilical Cord Milking
Comparing Delayed Cord Clamping and Umbilical Cord Milking During Elective Cesarean Section for the Neonatal Outcome
the study is conducted on the different actions on umbilical cord clamping including immediate cord clamping (ICC) , delayed cord clamping (DCC) for 30 seconds and umbilical cord milking (UCM) for 10-15 seconds in females that…
- Trial name
- NCT05951348
- Testing
- Delayed cord clamping for 30 seconds
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Alexandria University
Cleft Palate
Retrospective Study on the Outcome of Cleft Palate Repair: Comparing US Surgical and Ethicon Suture Materials
Investigator initiated retrospective chart review to study the effects of changing suture material on the healing and outcome of cleft palate surgery were.
- Trial name
- NCT00584272
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Davis
Clubfoot
Gait Analysis in Ponseti Clubfoot
Patients with clubfoot treated with the Ponseti method from a prospective database are evaluated using gait analysis including a foot model and a disease specific instrument score and compared to a group of healthy children.
- Trial name
- NCT02022267
- Where
- Austria
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Orthopedic Hospital Vienna Speising
Asphyxia Neonatorum
Biomarkers And Neurological Outcome in Neonates 2
Follow-up of participants of BANON1 study at age of at least 2 years. BANON1 (ClinicalTrials.gov ID: NCT03357250): Validation of biomarkers based on 24 months neuro-developmental outcome data in a human population for their…
- Trial name
- BANON2 (NCT04714775)
- Where
- 13 sites in Germany, Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- InfanDx AG
Gaucher Disease, Patient Reported Outcome
Digital Health Platform Customized for Patients With Gaucher Disease
The entry of digitization into the world in recent years is helping the health care system to operate more efficiently than in the past and has increased the participation of patients and their families in managing their health…
- Trial name
- NCT04997772
- Testing
- Digital Gaucher Platform
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Shoshana Vilk
Respiratory Distress Syndrome
Fetal Lung Volume and Pulmonary Artery Resistance Index Measurement in Term Diabetic Pregnancy
The aim of this study is to determine cut-off values for fetal lung volume by VOCAL and pulmonary artery resistance index by pulsed Doppler in fetuses of diabetic mothers, and correlate the results with postnatal respiratory…
- Trial name
- NCT02586922
- Testing
- Three-dimensional (3D) ultrasonography
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Preterm Infant Development, Preterm Infant Health
Neonatal Data and Biobank to Study Factors Influencing Development in Preterm Infants Born at <32 Weeks' Gestation and/or <1500 g Birth Weight
The Neo-Life project aims to establish a prospective neonatal data and biobank to investigate factors influencing the short- and long-term development of very preterm infants.
- Conditions
- Preterm Infant Development, Preterm Infant Health, Prematurity Complications, Premature Birth
- Trial name
- Neo-Life (NCT07490912)
- Where
- Germany
- Volunteers
- 1,300 people
- Sponsor
- University Hospital of Cologne
Cystic Fibrosis
Parameters to Assess Response to Intra-Venous Antibiotic Treatment for Pulmonary Exacerbations in Cystic Fibrosis
Cystic fibrosis (CF) is a multisystem disease characterized by viscid secretions in multiple organ systems. Lung infection and damage account for most of the disease burden.
- Trial name
- PRIVATE (NCT04016571)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Belfast Health and Social Care Trust
Gestational Diabetes Mellitus
Antioxidants in Gestational Diabetes
Fasting and two hours postprandial blood sugar were done to all cases between 28 and 32 weeks and high blood sugar levels were found so Cases were controlled by both diet and insulin.
- Trial name
- NCT02355197
- Testing
- L-ascorbic acid
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Congenital Heart Disease
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults
The main purpose of this proposal is to perform novel MRI analyses to determine the brain organizational changes associated with altered executive function and the modulating role of variants in neuroresilience and hypoxia…
- Trial name
- NCT05258981
- Testing
- MRI
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Molar Hypomineralization
Pulpotomy in Hypominerlized Permanent Molars.
The first permanent molars in children can sometimes develop a condition called molar-incisor hypomineralization (MIH), which affects the strength and quality of the tooth structure.
- Trial name
- NCT07756216
- Testing
- Step wise pulpotomy
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital