Clinical trials: Neonatal Outcome
Wilson Disease, Generalized Epilepsy
Clinical Features and Outcome of Wilson's Disease With Generalized Epilepsy in Chinese Patients
Generalized epilepsy is rarely reported in patients with Wilson disease (WD) and lacks experience in clinical practice. We aim to provide better experience for the diagnosis and treatment for WD patients with epilepsy in the…
- Trial name
- NCT04965571
- Testing
- genetic test
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pompe Disease
Long-term Outcome in Late-onset Pompe Disease Treated Beyond 36 Months (STIG-Pompe-Study)
Long-term outcome in late-onset Pompe disease treated beyond 36 months (ATBIG-Pompe-Study), a multicenter, multinational, longitudinal, non-interventional observational study in subjects, at least 8 years old, diagnosed with…
- Trial name
- STIG (NCT02824068)
- Testing
- glucosidase alfa
- Where
- 3 sites in Germany, Italy and 1 more
- Volunteers
- 112 people
- Sponsor
- LMU Klinikum
Duchenne Muscular Dystrophy
Outcome Measures in Duchenne Muscular Dystrophy: A Natural History Study
Novel emerging therapies for Duchenne Muscular Dystrophy (DMD) require a deeper understanding of DMD natural history. This study aim to assess the natural history of DMD through a composite assessment tool capable of capturing…
- Trial name
- NCT02780492
- Testing
- Set of assessment tools
- Where
- 5 sites in France, Netherlands and 1 more
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University College, London
Cystic Fibrosis
Gastrointestinal Study at Orkambi Therapy in CF Patients
Ivacaftor caused a significance increase in weight in patients carrying the G551D mutation and the etiology of this has largely remained unknown but may be due to improved function of the gastrointestinal tract.
- Trial name
- NCT03859531
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska University Hospital
Tracheo Esophageal Fistula
Outcome Predictors of Trachea-esophageal Fistula
In the present study, the investigator aim to evaluate the prevalence, factors affecting outcome and the outcome of neonates with tracheoesophageal fistula.
- Trial name
- NCT05847101
- Testing
- Tracheoesophageal fistula repair
- Volunteers
- 100 people
- Sponsor
- Assiut University
Dialysis Access Malfunction, End Stage Renal Failure on Dialysis
MAgicTouch™ Intervention Leap for Dialysis Access (MATILDA) Trial
For patients with End Stage Renal Failure (ESRF), the surgical creation of an Autogenous Arteriovenous Fistula (AVF) or Autogenous Arteriovenous Graft (AVG) is the recognised standard for providing vascular access.
- Conditions
- Dialysis Access Malfunction, End Stage Renal Failure on Dialysis, End Stage Renal Disease, Fistulas Arteriovenous
- Trial name
- MATILDA (NCT04698512)
- Testing
- AVFistuloplasty with Sirolimus coated balloon
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Singapore General Hospital
Huntington's Disease
FuRST 2.0 Cognitive Pre-Testing
The FuRST 2.0 scale is being developed as a Patient Reported Outcome (PRO) with information coming directly from the Huntington's Disease Gene Expansion Carrier (HDGEC) and companion through self-report.
- Trial name
- NCT02881931
- Testing
- FuRST 2.0
- Where
- 4 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- CHDI Foundation, Inc.
Hemophilia A
Clinical and Health-related Outcome of rFVIIIFc Prophylaxis
Current standard therapy for patients with haemophilia (PwH) in the prevention of bleeding episodes is a prophylactic intravenous treatment with recombinant coagulation factor (F) VIII (Haemophilia A) or rather FIX (Haemophilia…
- Trial name
- CLHEAR (NCT04583930)
- Where
- 2 sites in Germany
- Volunteers
- 48 people
- Sponsor
- Prof. Dr. Dr. Thomas Hilberg
Umbilical Cord Milking
Comparing Delayed Cord Clamping and Umbilical Cord Milking During Elective Cesarean Section for the Neonatal Outcome
the study is conducted on the different actions on umbilical cord clamping including immediate cord clamping (ICC) , delayed cord clamping (DCC) for 30 seconds and umbilical cord milking (UCM) for 10-15 seconds in females that…
- Trial name
- NCT05951348
- Testing
- Delayed cord clamping for 30 seconds
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Alexandria University
Hemophilia
Canadian CHO-KLAT/H-FIT Study - Quality of Life of, and Burden of Caring for, Persons With Hemophilia
The primary goal of this observational study is to determine if: health-related quality of life of boys with moderate/severe hemophilia A who are followed in Canadian pediatric hemophilia treatment centres is significantly…
- Trial name
- NCT06191068
- Where
- Canada
- Volunteers
- 190 people
- Sponsor
- The Hospital for Sick Children
Bronchopulmonary Dysplasia
Respiratory Management of Preterm Infants and Bronchopulmonary Dysplasia
This observational study evaluates the impact of respiratory management modifications implemented in our institution on the intubation rates and the death or Bronchopulmonary Dysplasia (BPD) outcome.
- Trial name
- NCT03411018
- Testing
- Mechanical ventilation exposure
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Manuel Sanchez Luna
Tuberous Sclerosis Complex
Clinical Presentation and Renal Outcome of Patients With Tuberous Sclerosis Complex and/or Renal Angiomyolipoma in the Great West Region of France
This study aims to investigate the factors (clinical, care-related and genetic) affecting renal outcome in patients with TSC (Tuberous sclerosis complex)
- Trial name
- TSAR (NCT02887781)
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Adult Congenital Heart Disease, Cardiac Surgery
Multicenter Validation of a Predictor Model of ACHD Patients and Cardiac Surgery
This multicentre study is to validate prediction modeling for the ACHD population undergoing cardiac surgery. The validation of this prediction model will support and generalize its use as a risk stratification tool in the ACHD…
- Trial name
- NCT04787705
- Where
- Canada
- Volunteers
- 547 people
- Sponsor
- University Health Network, Toronto
White Matter Abnormalities, Nonspecific, ADHD
Predicting the Outcome of ADHD in White Matter Injure Neonates With Multi-modality MRI
The goal of this bidirectional observational cohort study is to investigate the longitudinal relationship between neonatal white matter injury (WMI) and the subsequent development of attention-deficit/hyperactivity disorder…
- Conditions
- White Matter Abnormalities, Nonspecific, ADHD, Neurodevelopment Outcome
- Trial name
- NCT07836244
- Where
- 9 sites in China
- Volunteers
- 348 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Pregnancy Complications, Pregnancy Outcome
BioThrax® (Anthrax) Vaccine in Pregnancy Registry
The purpose of this study is to determine if inadvertent receipt of the BioThrax vaccine during pregnancy is independently associated with adverse maternal, pregnancy, or infant health outcomes.
- Conditions
- Pregnancy Complications, Pregnancy Outcome, Congenital Abnormalities
- Trial name
- NCT01653392
- Testing
- Observational Intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Cystinosis
Development of Health-related Quality of Life Instrument for Patients With Cystinosis
Cystinosis is a rare congenital, inherited metabolic disorder that results in the storage of cystine in the cells of many organs of the body.
- Trial name
- QUALIFY (NCT05959668)
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Cystinose Stiftung
Dislocation, Tooth, Teeth, Endodontically-Treated
Treatment Result of Zirconia Laminate Veneer
This study aims to evaluate the clinical performance of the zirconia laminate veneer, a minimally invasive prosthetic restoration
- Conditions
- Dislocation, Tooth, Teeth, Endodontically-Treated, Tooth Fracture, Tooth Injuries
- Trial name
- NCT06406582
- Testing
- Zirconia laminate veneer, Lithium Disilicate laminate veneer
- Where
- Vietnam
- Volunteers
- 50 people
- Sponsor
- Hanoi Medical University
Transient Hypothyroxinemia of Prematurity, Neurodevelopmental Abnormality
ASQ Scores of Transient Hypothyroxinemia of Prematurity
Transient hypothyroxinemia of prematurity (THoP) is defined as free thyroxine (FT4) level is below the reference values despite normal TSH level in preterm infant.
- Trial name
- NCT05901623
- Testing
- 'Ages and Stages Questionnaries' (ASQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pediatrics, Neurological Abnormality
Turkish Version of the BRIEF-Hammersmith Infant Neurological Examination (HINE)
The American Academy of Pediatrics defines infants at risk as those with preterm birth, special health care needs, family risk factors, and those at risk of early death.
- Conditions
- Pediatrics, Neurological Abnormality, Neurodevelopment Outcome
- Trial name
- BRIEF-HINE (NCT07182474)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cerebellar Hypoplasia
Long-term Outcome of Newborns With an Isolated Small Cerebellum
The decreased cerebellar biometry during second and third trimester ultrasound examination is the main parameter to diagnoses cerebellar and pontocerebellar hypoplasia.
- Trial name
- PECERI (NCT03572868)
- Testing
- Evaluation of the long term neurodevelopmental outcome
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Hospices Civils de Lyon