Clinical trials: Neonatal Respiratory Depression
Mechanical Ventilation Pressure High, Ventilator-Associated Pneumonia (VAP)
Dynamic Airway Resistance & ML: Guide Sputum Suction in Ventilated Patients
Research has shown that timely suctioning not only improves survival rates but also enhances the quality of life in ventilator-dependent patients.
- Conditions
- Mechanical Ventilation Pressure High, Ventilator-Associated Pneumonia (VAP), Respiratory Depression Neonatal
- Trial name
- NCT07375667
- Testing
- The dynamics of airway resistance, conventional suctioning
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Affiliated Hospital of Nantong University
Respiratory Depression Neonatal
Bedside Improvement of Resuscitation Through mHealth Feedback (BIRTH Study)
Purpose: To evaluate the effectiveness of newborn resuscitation feedback supported by a mobile health application called LIVEBORN; secondarily, to evaluate the relative effectiveness of real-time guidance vs debriefing.
- Trial name
- NCT05963516
- Testing
- LIVEBORN: A Mobile Health Application (app) for Newborn Resuscitation, NeoBeat: Heart Rate Meter for Newborn Resuscitation
- Where
- 4 sites in Democratic Republic of the Congo
- Volunteers
- 14,679 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Staphylococcus Aureus Pneumonia, Lung Diseases
Mucoid Staphylococcus Aureus in Cystic Fibrosis Airways
Recently, the investigators described a new mucoid phenotype of Staphylococcus aureus cultured from the airways of cystic fibrosis (CF) patients.In this observational study, the investigators plan to determine the prevalence of…
- Conditions
- Staphylococcus Aureus Pneumonia, Lung Diseases, Cystic Fibrosis, Lung Function Decreased
- Trial name
- mucostaph (NCT04171583)
- Where
- 13 sites in Austria, Germany
- Volunteers
- 628 people
- Sponsor
- University Hospital Muenster
Cystic Fibrosis
Prevalence and Impact of Depression and Anxiety in Cystic Fibrosis
The Impact of cystic fibrosis (CF) on psychological and emotional functioning has been the focus of several studies over the past 20 years.
- Trial name
- ADMPE-2 (NCT03424486)
- Testing
- Questionnaires
- Where
- 8 sites in France
- Volunteers
- 108 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Educational Videos
Preoperative Educational Videos on Maternal Stress Whose Children Received Congenital Heart Disease Surgery: During COVID-19 Panic
During COVID-19 panic, we examined if educational digital video disk can reduce maternal uncertainty, anxiety and depression if their children undergo congenital heart disease surgery and when surgical or post-surgical…
- Conditions
- COVID-19, Educational Videos, Maternal, Uncertainty
- Trial name
- NCT06107491
- Testing
- Preoperative educational videos plus routine education, Preoperative routine education
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chung Shan Medical University
Cystic Fibrosis, Siblings
The Development and Evaluation of iCF-PWR for Healthy Siblings of Individuals With Cystic Fibrosis
The goal of the clinical trial is to test whether a mental health program that is delivered through the Internet works well for healthy children and adolescents with siblings with cystic fibrosis (CF).
- Conditions
- Cystic Fibrosis, Siblings, Mental Health, Internet-based Intervention
- Trial name
- NCT06012084
- Testing
- Internet-delivered Cystic Fibrosis Mental Health Prevention, Wellness, and Resource (iCF-PWR) program
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Regina
Cystic Fibrosis, Depression
Pilot Study of a CF-specific CBT Intervention for Adolescents
The goal of this study is to pilot a new CF-specific cognitive-behavioral therapy intervention (CF-CBT-A) for prevention and treatment of depression and anxiety for adolescents with CF.
- Conditions
- Cystic Fibrosis, Depression, Anxiety
- Trial name
- NCT05271643
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Infant, Newborn, Hypoxia-Ischemia, Brain
Whole-Body Cooling for Birth Asphyxia in Term Infants
This large multicenter trial tested whether cerebral cooling initiated within 6 hours of birth and continued for 72 hours would reduce the risk of death and moderate to severe neurodevelopmental injury at 18-22 months corrected…
- Trial name
- NCT00005772
- Testing
- Induced hypothermia, Control
- Where
- 16 sites in United States
- Volunteers
- 208 people
- Sponsor
- NICHD Neonatal Research Network
Hypoxic Ischemic Encephalopathy
Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy
The goal is to see whether topiramate (an anti-epileptic agent) improves the outcome of babies with neonatal hypoxic encephalopathy who are receiving whole body cooling.
- Trial name
- NCT01765218
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Kristin R Hoffman
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Cystic Fibrosis, Anxiety
Project UPLIFT to Reduce Anxiety and Depression in CF Patients
People with CF have elevated rates of anxiety and depression when compared to the general population. Anxiety and depression can have a negative impact on adherence and disease self-management, leading to worse CF health outcomes…
- Conditions
- Cystic Fibrosis, Anxiety, Depression
- Trial name
- NCT03139266
- Testing
- UPLIFT, Treatment as usual
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Virginia Commonwealth University
Depression, Cystic Fibrosis
Pilot Trial of Phototherapy for Acute Depression in Hospitalized Cystic Fibrosis Patients
The purpose of this study is to determine whether bright light phototherapy can improve depressive symptoms in hospitalized patients with cystic fibrosis (CF) with subsequent effects on quality of life and illness recovery.
- Trial name
- PHOTO (NCT01822197)
- Testing
- Phototherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nationwide Children's Hospital
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health
Depression, Anxiety
Preventing Depression and Anxiety: A Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention
Individuals with Cystic Fibrosis (CF) are at high risk for depression and anxiety, with negative consequences for quality of life, ability to carry out daily CF treatments, and health.
- Trial name
- NCT03992027
- Testing
- CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis, Waitlist Control
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Asthma, Allergic Rhinitis
Evaluation of an Integrated Care Project
The purpose of the study is to investigate the effectiveness and cost-effectiveness of the integrated care program of a statutory health insurance offering additional homeopathic treatment to their members
- Conditions
- Asthma, Allergic Rhinitis, Atopic Eczema, Migraine
- Trial name
- ediva (NCT01854580)
- Where
- Germany
- Volunteers
- 3,960 people
- Sponsor
- Charite University, Berlin, Germany
Infant, Newborn, Hypoxia, Brain
Late Hypothermia for Hypoxic-Ischemic Encephalopathy
This study is a randomized, placebo-controlled, clinical trial to evaluate whether induced whole-body hypothermia initiated between 6-24 hours of age and continued for 96 hours in infants ≥ 36 weeks gestational age with…
- Conditions
- Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic
- Trial name
- NCT00614744
- Testing
- Hypothermia, Normothermic Control
- Where
- 22 sites in United States
- Volunteers
- 168 people
- Sponsor
- NICHD Neonatal Research Network
Lung Cancer, Radiation-Induced Disorder
Functional Lung Avoidance SPECT-guided Radiation Therapy of Lung Cancer
Study aims to determine if functional lung avoidance based on perfusion single photon emission (SPECT)/CT scan, improves toxicity outcomes for patients with advanced lung cancer undergoing chemo-radiotherapy.
- Conditions
- Lung Cancer, Radiation-Induced Disorder, Radiation Pneumonitis, Pulmonary Disease
- Trial name
- ASPECT (NCT04676828)
- Testing
- Single-photon-emission CT scan
- Where
- 2 sites in Australia, Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Cystic Fibrosis
Impact of the Introduction of ORKAMBI on Anxiety, Depression, Quality of Life and Adherence of Adolescents and Young Adults
The aim of this project is to evaluate the psychological reshuffle induced by ORKAMBI. The particular focus of this study is the consequence of its introduction on anxiety, depression, quality of life and adherence to all cystic…
- Trial name
- ORK-AJA (NCT03659214)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris