Clinical trials: Neonatal Resuscitation
Intraventricular Hemorrhage
Neonatal Resuscitation With Intact Cord
The purpose of this study is to examine whether providing ventilation during delayed umbilical cord clamping provides greater placental transfusion and improved hemodynamic transition at birth.
- Trial name
- NRIC (NCT02231411)
- Testing
- V-DCC, Delayed cord clamping, Dry and and if apneic initially can stimulate by gently rubbing the back for approximately 30 seconds with warm sterile towels
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Sharp HealthCare
Hypofibrinogenemia, Hemorrhage
Cryo-FIRST: Effectiveness of INTERCEPT Fibrinogen Complex (IFC) for Trauma-Associated Hemorrhage
The objective of this multicenter, single-arm, observational study is to determine the feasibility and effectiveness of early administration of FDA-approved, pre-thawed Pathogen Reduced Cryoprecipitated Fibrinogen Complex…
- Conditions
- Hypofibrinogenemia, Hemorrhage, Trauma Associated Hemorrhage, Hemorrhagic Shock
- Trial name
- CRYO-FIRST (NCT07218185)
- Testing
- Pathogen Reduced Cryoprecipitated Fibrinogen Complex
- Where
- 4 sites in United States
- Volunteers
- 320 people
- Sponsor
- Cerus Corporation
Pregnancy
The Effect of SCIM on Neonatal Resuscitation
In this randomized controlled trial 48 students were randomly allocated in three groups SCIM, Video training (VT) and control group(no training). They had a workshops based on NRP and lasted 6 hours for each group.
- Trial name
- NCT02082964
- Testing
- SCIM, video
- Where
- Iran
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Congential Absence of Heart Structure, Congenital Malformation of Heart, Unspecified
Initiation of Resuscitation While Attached to the Cord With Congenital Heart Disease
Before birth, the placenta (a structure with many blood vessels attached to the inside of your womb) and the umbilical cord (the umbilical cord is attached to the placenta) are sending oxygen and nutrients from the mother's blood…
- Conditions
- Congential Absence of Heart Structure, Congenital Malformation of Heart, Unspecified, Hypoplastic Left Heart Syndrome, TGA - Transposition of Great Arteries
- Trial name
- INSPIRE-CHD (NCT03690245)
- Testing
- Initiation of Resuscitation While Attached to the Cord
- Where
- Canada
- Sponsor
- University of Alberta
Hypothermia, Newborn
Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates
The overall hypothesis is that placing infants 1000-2500 grams in plastic bags when compared to routine care will reduce the risk of hypothermia (< 36.5 degrees C) without increasing hyperthermia (> 37.5 degrees C).
- Trial name
- NCT01403623
- Testing
- Resuscitation and post resuscitation care with plastic bag, Resuscitation- no plastic bag for temperature regulation
- Where
- Zambia
- Volunteers
- 106 people
- Sponsor
- University of Alabama at Birmingham
Neonatal Resuscitation, Simulation
ECG Monitoring During NRP: a False Sense of Security?
ECG monitoring is relatively new mode of monitoring in the delivery room. While its use has been positively received by many practitioners of NRP, concerns have been raised about delaying chest compressions for a pulseless baby…
- Trial name
- NCT03660033
- Testing
- ECG in delivery room
- Volunteers
- 60 people
- Sponsor
- St. Justine's Hospital
Asphyxia Neonatorum
First Breath: Neonatal Resuscitation in Developing Countries
In developing countries, neonatal death from birth asphyxia is a major problem. This study will be conducted in several countries to determine if the combined Neonatal Resuscitation Program/Essential Newborn Care Program compared…
- Trial name
- NCT00136708
- Testing
- Neonatal Resuscitation
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 120,009 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Birth Asphyxia
Echocardiography Sub-Study of the Umbilical Cord Milking in Non-Vigorous Infants Trial (MINVI)
Non-vigorous infants enrolled in the MINVI trial will be approached for consent for ongoing data collection. As part of the data collection, an optional echocardiogram will be performed if the parent consents.
- Trial name
- NCT03798093
- Testing
- Umbilical Cord Milking, Early Cord Clamping
- Where
- United States
- Volunteers
- 227 people
- Sponsor
- Sharp HealthCare
Newborn Resuscitation, Heart Rate Monitoring
The NeoBeat Efficacy Study for Newborns
In a multicenter randomized controlled trial the investigators will evaluate the efficacy of the novel heart rate meter NeoBeat on ventilation performance and short-term outcomes compared to standard care in newborns in need of…
- Trial name
- NCT03849781
- Testing
- NeoBeat with a visible display
- Where
- Norway
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Traumatic Hemorrhage, Coagulopathy
Factor In the Initial Resuscitation of Severe Trauma 2 Patients
Injury is the leading cause of death for people between the ages of 1-44. This is especially true in trauma patients who have bleeding complications.
- Conditions
- Traumatic Hemorrhage, Coagulopathy, Massive Hemorrhage
- Trial name
- FiiRST-2 (NCT04534751)
- Testing
- Fibrinogen + PCC, Frozen Plasma
- Where
- 6 sites in Canada
- Volunteers
- 142 people
- Sponsor
- University Health Network, Toronto
Asphyxia, Resuscitation
Resuscitation Table Height for Face-mask Ventilation in Infants
Positive pressure ventilation (PPV) is the most important intervention in neonatal resuscitation. During PPV, it is important to hold the face-mask with care, as applying excessive pressure could cause injury to the infant, while…
- Conditions
- Asphyxia, Resuscitation, Newborn Morbidity
- Trial name
- ForTab (NCT06254651)
- Testing
- High resuscitation table, Low resuscitation table
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Prematurity, Eye Fundus
Benefit of Singing in the Care of Premature Children Undergoing Screening for Retinopathy of Prematurity in the Neonatology and Neonatal Resuscitation Unit of the Dijon University Hospital
As part of the regular procedure for premature births, premature infants undergo several screening examinations, including an examination of the fundus.
- Trial name
- Voix Chantée (NCT03830580)
- Testing
- Positive stimulation (singing)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Neonatal Asphyxia
Randomized Cluster Trial on Innovative and Standard Strategies for Neonatal Resuscitation Training (RCPNEOPERU Project)
Background: About 10% of all newborns may have difficulty breathing and require support by trained personnel. In Peru, 90% of deliveries occur in health facilities; however there is not a national neonatal resuscitation and…
- Trial name
- RCPNEOPERU (NCT03210194)
- Testing
- Standard Neonatal Resuscitation Training, MP-ICT Neonatal Resuscitation Training
- Where
- Peru
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Nursing Students Education on Neonatal Resuscitation
The Impact of Pedagogical Framework in Education of Neonatal Resuscitation
Virtually 10% of newborns suffer respiratory distress at birth thus need intervention from proficient health professionals. Pakistan is one of the top ten countries that carry two-thirds of the global burden of neonatal deaths.
- Trial name
- NCT04748341
- Testing
- Pedagogical Framework (Learn, See, Practice, Prove, Do, and Maintain), Traditional Method
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Extreme Prematurity - Less Than 28 Weeks
Study of Room Air Versus 60% Oxygen for Resuscitation of Premature Infants
The most appropriate initial oxygen concentration for the resuscitation of the extremely low birth weight infant has not been established using large well designed, randomized, blinded, prospective trials and the level of oxygen…
- Trial name
- PRESOX (NCT01773746)
- Testing
- Neonatal Resuscitation
- Where
- 22 sites in United States, Austria and 10 more
- Volunteers
- 80 people
- Sponsor
- Sharp HealthCare
Cardiopulmonary Resuscitation, Newborn Asphyxia
Comparison of Visual Instructions for Inserting a Laryngeal Mask in a Neonatal Mannequin.
This research project compares the effectiveness of two visual instructions for inserting laryngeal masks. Researchers will assess the procedure performed by undergraduate health students on neonatal mannequins.
- Trial name
- Neo-LMi (NCT06502327)
- Testing
- Instructions A, Instructions B
- Where
- Peru
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National University of San Marcos, Peru
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Infant, Premature
Early Skin to Skin in Neonatal Reanimation
In the reanimation neonatal department of the Nice's hospital, 34% of newborns admitted have an umbilical vein catheter (KTVO). Their parents are admitted 24h/24h by their side, where everything is done to set up the Attachment…
- Trial name
- PA2PRéaNice (NCT03171844)
- Testing
- Skin to skin
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Renal Failure
Renal Replacement Therapy in Neonates
The circumstances for setting up dialysis in the neonatal period are multiple: congenital anomaly of the kidney and urinary tract (CAKUT), secondary acute renal failure whose etiologies are multiple (sepsis, hypovolemia…
- Trial name
- Neo-Renal (NCT05456659)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Strasbourg, France
Respiratory Failure, Premature Neonates
Supraglottic Airway for Resuscitation in Preemies
The goal of this single-arm intervention trial is to learn whether using a supraglottic airway (SA) as the primary interface for positive pressure ventilation (PPV) is feasible during delivery room resuscitation of premature…
- Conditions
- Respiratory Failure, Premature Neonates, Delivery Room Resuscitation, Positive Pressure Ventilation
- Trial name
- SUPREEMIE (NCT07419438)
- Testing
- Supraglottic Airway
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania