Clinical trials: Neonatal Surgery
Complex Regional Pain Syndrome I (CRPS I), Nerve Entrapment Syndrome
Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical Study
This clinical study evaluates the effectiveness of surgical treatment in patients with upper-limb complex regional pain syndrome (CRPS) diagnosed according to the Budapest criteria.
- Trial name
- CRPS-SURG (NCT07263256)
- Testing
- Lesion-Specific Surgical Correction, Median Nerve Decompression
- Where
- Czechia
- Volunteers
- 74 people
- Sponsor
- Jitka Fricova
Coronary Disease
Platelet Activation Markers in Pediatric Cardiac Surgery
In this study the focus will be on correlating the levels of platelet activation markers (proteins that are released when blood cells are activated)to the duration of cardiopulmonary bypass, temperature during cardiopulmonary…
- Trial name
- NCT00450151
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weill Medical College of Cornell University
Arteriovenous Fistula
Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery
The investigators designed a prospective randomized study to compare the conventionally used sedative drug propofol with a latest alternative dexmedetomidine (DEX), in patients with end-stage renal disease undergoing…
- Trial name
- NCT02447796
- Testing
- Propofol, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Von Hippel-Lindau Disease, Central Nervous System Hemangioblastoma
Pediatric Von Hippel-Lindau Disease: Natural History, Predictive Factors, and Long-Term Functional Outcomes of Central Nervous System Hemangioblastomas
Von Hippel-Lindau (VHL) disease is a rare hereditary cancer predisposition syndrome associated with the development of central nervous system hemangioblastomas from childhood.
- Trial name
- VHL-PED-CHB (NCT07705529)
- Where
- 3 sites in France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bowel Obstruction, Bowel Ischemia
Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at two to three time points during procedures of…
- Conditions
- Bowel Obstruction, Bowel Ischemia, Diverticulitis, Abnormality of the Gastrointestinal Tract
- Trial name
- NCT04709445
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Cardiac Surgery
HLA-DR Expression in Neonates After Cardiac Surgery Under Cardiopulmonary Bypass
The purpose of this study is to determine how monocyte HLA-DR and other markers of immune function change with time in neonates who underwent cardiac surgery with cardiopulmonary bypasss.
- Trial name
- IMMUNOPED (NCT03309839)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Von Hippel-Lindau Disease
Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease
Von Hippel-Lindau disease (VHL) is an inherited cancer syndrome. Patients are at risk for developing pancreatic cysts and tumors. These tumors are more aggressive in some people than in others.
- Trial name
- NCT00062166
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Cancer Institute (NCI)
Cerebrovascular Disease, Arteriovenous Malformations
Research on Hybrid Operation Technique in the Treatment of Complex Brain Arteriovenous Malformations
Complex brain arteriovenous malformations (bAVMs) in ≥3 Spetzler-Martin grades have long been challenges among cerebrovascular diseases.
- Conditions
- Cerebrovascular Disease, Arteriovenous Malformations, Complex; Primary
- Trial name
- HOTAVM (NCT03774017)
- Testing
- one-staged hybrid operation, Traditional microsurgical operation
- Where
- 7 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Eyelid Dermatochalasis, Dermatochalasis
Restorative Eye Treatment and INhance in Upper Eyelid Blepharoplasty Surgery
The purpose of this research is to determine if restorative eye treatment (RET) and Inhance with trihex technology used before and after blepharoplasty can lead to better skin quality before undergoing blepharoplasty, and if…
- Trial name
- NCT05007288
- Testing
- Restorative Eye Treatment (RET) cream, INhance with Trihex Technology
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Miami
Hypoplastic Left Heart Syndrome
Study of Intramyocardial Injection of Ventrix Bio Extracellular Matrix (VentriGel) to Assess the Safety and Feasibility in Pediatric Patients with Hypoplastic Left Heart Syndrome (HLHS)
The goal of this Phase I Open-Label study is to demonstrate the safety and feasibility of VentriGel injection in children with Hypoplastic Left Heart Syndrome (HLHS).
- Trial name
- NCT06461676
- Testing
- Ventrix Bio Extracellular Matrix
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Emory University
Knee Osteoarthritis, Bone; Deformity, Congenital
COREV 2.0 PMCF-Study on Manual and Navigated Revision Knee Patients
The Columbus® Revision endoprosthetic system is bearing the CE-mark. This means that within the scope of this observational study the patient will not be subjected to any additional stressful, study-related medical examinations…
- Conditions
- Knee Osteoarthritis, Bone; Deformity, Congenital, Prosthesis Failure, Prosthesis-Related Infections
- Trial name
- COREV (NCT05113303)
- Testing
- Navigated Revision Total Knee Arthroplasty, Manual Revision Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Vaginal Delivery, Surgical Site Infection
Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery
This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with…
- Trial name
- NCT05122169
- Testing
- Povidone-Iodine, Chlorhexidine
- Volunteers
- 4,140 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Congenital Disorders
Repeat Sternotomy for Pediatrics
Given the relative lack of information regarding the risks associated with repeat sternotomy in the pediatric patient population, a preliminary screen of the Children's Cardiothoracic Surgery Database was performed to determine…
- Trial name
- NCT00485745
- Volunteers
- 1,281 people
- Sponsor
- Children's Healthcare of Atlanta
Developmental Dysplasia of the Hip (DDH)
Early Outcomes of Arthroscopic Versus Open Reduction for Developmental Dysplasia of the Hip in Children
This study was designed to determine whether arthroscopic-assisted reduction offers better early surgical outcomes than open reduction for treating developmental dysplasia of the hip in children.
- Trial name
- NCT06747767
- Testing
- Arthroscopy, Open reduction
- Where
- Iraq
- Volunteers
- 43 people
- Sponsor
- Hawler Medical University
Velopharyngeal Insufficiency
Submucosa/Mucosal Pharyngeal Flap Trial
The investigators want to compare two different surgical techniques for the treatment of a condition called velopharyngeal dysfunction (VPD).
- Trial name
- NCT03187600
- Testing
- Mucosa/submucosa Pharyngeal Flap, Standard of Care Pharyngeal Flap
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypospadias, Urinary Diversion
Evaluation of the Method and Duration of Urinary Diversion in the Management of Distal Penile Hypospadias Following Surgical Repair.
This study aims to conduct a head-to-head comparison to determine the optimal method and duration of urinary diversion following distal penile hypospadias repair.
- Trial name
- NCT07421271
- Testing
- Application of urethral catheter alone for 1 week., Application of urethral catheter alone for 2 weeks., Application of urethral stent and suprapubic catheter for 1 week
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Ain Shams University
Tethered Cord, Tethered Cord Syndrome
Investigation of Surgical Sectioning of the Filum Terminale in Treating Occult Tethered Cord Syndrome Patients
The investigators hypothesize that surgical release of the filum terminale (strand of fibrous tissue at the end of the spinal cord) is a more efficacious treatment option for symptomatic relief than medical management in subjects…
- Conditions
- Tethered Cord, Tethered Cord Syndrome, Occult Spina Bifida, Spina Bifida Occulta
- Trial name
- OCCULT (NCT05163899)
- Testing
- Release of filum terminale
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Craniosynostosis
Pleth Variability Index Monitoring in Pediatric Craniosynostosis Surgery
This prospective observational study aims to evaluate the role of pleth variability index (PVI) and perfusion index (PI) monitoring in intraoperative hemodynamic control among pediatric patients undergoing craniosynostosis…
- Trial name
- PVI-CRANIO (NCT07657598)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Muzaffer GENCER
Kidney Failure, Chronic
Effect of Exercise on Endothelial Function and Vascular Compliance in Chronic Kidney Disease
The study hypothesis is that 6 weeks of repetitive handgrip exercise will improve endothelial function and venous compliance in pre-dialysis patients with an estimated glomerular filtration rate of less than or equal to 20…
- Trial name
- NCT01068314
- Testing
- Repetitive arm exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Iowa
Molar, Fourth, Extracting Own Teeth
Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery
The goal of this clinical trial is to evaluate whether the topical application of Novox® Drop on surgical wounds after the extraction of lower third molars can have a clinical advantage.
- Conditions
- Molar, Fourth, Extracting Own Teeth, Edema Face, Pain
- Trial name
- NCT06458478
- Testing
- Hyper-oxygenated gel, glycerin based gel
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Azienda Ospedaliera di Perugia
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