Clinical trials: Neonatal Surgery
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Congenital Heart Disease in Children
How to Report Postoperative Outcomes After a Paediatric Cardiac Surgery ?
Congenital heart disease is a common abnormality in newborns. The marked improvement in the surgical management of congenital heart disease has led to a reduction in postoperative mortality, historically a quality criterion for…
- Trial name
- Pedia-Card (NCT05546983)
- Where
- France
- Volunteers
- 189 people
- Sponsor
- University Hospital, Strasbourg, France
Congenital Disorders
Intra-Atrial vs. Extra-Cardiac Technique During Fontan Operation
Our aim is a retrospective chart review seeking to determine any differences in the main clinical and outcome variables as well as general outcome data such as functional recovery, readmission rates, somatic growth and mortality.
- Trial name
- NCT00266942
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Children's Healthcare of Atlanta
Ulcerative Colitis, Colorectal Cancer
Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch…
- Conditions
- Ulcerative Colitis, Colorectal Cancer, Crohn Disease, Familial Adenomatous Polyposis
- Trial name
- NCT04695964
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Low Cardiac Output Syndrome, Transposition of Great Vessels
Nitric Oxide During Bypass for Arterial Switch Operation
This trial will test if adding nitric oxide (NO) gas to the cardiopulmonary bypass (CPB) circuit in infants undergoing an arterial switch operation (ASO) for Transposition of the Great Arteries (TGA) changes the incidence of…
- Trial name
- NASO (NCT03661385)
- Testing
- Nitric Oxide
- Where
- 4 sites in Australia, Canada and 2 more
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
Congenital Heart Disease
Custodiol Versus Blood Cardioplegaia in Paediatric Cardiac Surgery
Cardioplegic arrest is an essential part of cardiac surgery which aims to allow myocardial preservation and minimise myocardial swelling ,while providing a motionless and bloodless field ,.Blood cardioplegia has proven its…
- Trial name
- NCT03082716
- Testing
- Custodiol Solution, Blood cardioplegia
- Where
- Saudi Arabia
- Volunteers
- 49 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Organ Protection
Effect of Intravenous Lidocaine on Serum miRNA-135a in Patients Undergoing Non-cardiac Surgery
The purpose of this study is to investigate the effects of intravenous lidocaine on serum miRNA-135a and its downstream proteins Rock2 and Add1 in elderly patients undergoing non-cardiac under general anesthesia.
- Trial name
- NCT05503043
- Testing
- Lidocaine, Normal saline
- Volunteers
- 50 people
- Sponsor
- General Hospital of Ningxia Medical University
Single-ventricle, Congenital Heart Disease
Fontan Imaging Biomarkers (FIB) Study
The goal of the Fontan Imaging Biomarkers (FIB) study is to identify the associations of blood and urine biomarkers to imaging parameters of ventricular mechanics.
- Trial name
- FIB (NCT03119090)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Lipodystrophy, Deformities
Performance and Safety of the Lipo-transfer Cannulas in Patients Underlying Lipofilling Treatment
The purpose of this post-market clinical follow up study is to assess the safety and performance of Aesthetic Group cannulas. The study will evaluate the outcome of the Aesthetic Group cannulas range over a period of 1 month…
- Trial name
- NCT06089759
- Where
- 3 sites in France
- Volunteers
- 108 people
- Sponsor
- Aesthetic Group
CHD - Congenital Heart Disease
Feasibility of Home Telemonitoring of Infants With Congenital Heart Disease Awaiting Surgery During the First Year of Life
Actually, there is no telemonitoring program that includes newborns or infants with congenital heart disease awaiting cardiac intervention.
- Trial name
- Blue-Line (NCT06998290)
- Testing
- Blue-Line home telemonitoring program
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Maxillofacial Abnormalities
Mandibular Stability and Dentofacial Deformity
The present study intends to clarify whether there is positional mandibular stability in patients to be submitted to orthognathic surgery.
- Trial name
- NCT01486069
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hirschsprung Disease
Minimally Invasive Surgical Intervention for Hirschsprung's Disease in Pediatric Patients
Hirschsprung's disease (HD) is a congenital disorder characterized by the absence of enteric ganglion cells in the distal bowel, leading to functional obstruction, delayed meconium passage in neonates, and chronic defecation…
- Trial name
- NCT06874686
- Testing
- Minimally invasive laparoscopic pull-through surgery
- Where
- Vietnam
- Volunteers
- 1,050 people
- Sponsor
- National Children's Hospital, Vietnam
Marfan Syndrome, Lens Subluxation or Dislocation
Surgical Treatment of Marfan Syndrome With Subluxation Lens
To analyze the postoperative visual effects, and to compare the safety and efficacy of different surgical treatment with of Marfan Syndrome with subluxation lens.
- Trial name
- NCT05578469
- Testing
- surgical treatment of Marfan Syndrome with subluxation lens
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intestinal Atresia, Necrotizing Enterocolitis
The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.
Background: Intestinal resections are commonly performed in the pediatric population. Perfusion of the bowel is one of the most important factors determining the viability of an intestinal anastomosis.
- Conditions
- Intestinal Atresia, Necrotizing Enterocolitis, Hirschsprung Disease, Gastroschisis
- Trial name
- NCT04020939
- Testing
- SPY imaging, Indocyanine Green
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Esophageal Atresia, Enhanced Recovery After Surgery
Application of Enhanced Recovery After Surgery for Congenital Esophageal Atresia During Perioperative Period
The purpose of this prospective cohort study is to evaluate the safety and effectiveness of enhanced recovery after surgery (ERAS) to perform routine thoracoscopic repair for elective esophageal atresia type C
- Trial name
- ERASforCEA (NCT04072419)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Congenital Afibrinogenemia, Hypofibrinogenemia
FIB Grifols Congenital Deficiency for On-demand Treatment and Surgical Prophylaxis
This is a phase 3, multi-center, prospective, open-label, single-arm, clinical trial to be carried out in subjects with congenital fibrinogen deficiency manifested as afibrinogenemia or severe hypofibrinogenemia.
- Trial name
- NCT04636268
- Testing
- FIB Grifols
- Sponsor
- Instituto Grifols, S.A.
Cervical Spondylotic Myelopathy
Fusion or no Fusion After Decompression of the Spinal Cord in Patients With Degenerative Cervical Myelopathy
Background: Degenerative cervical myelopathy (DCM) is characterized by neck pain, neck stiffness, weakness, paresthesia, sphincter disturbance and balance disorder.
- Trial name
- MyRanC (NCT04936074)
- Testing
- Muscle preserving selective laminectomy, Laminectomy with instrumented fusion
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University Hospital
Hypospadias, Undescended Testis
Visual Guidelines and Tutoring in Pediatric Urological Surgery
The aim of this study is checking impact of visual guidelines (picture book) and tutoring in pediatric urologic surgery
- Conditions
- Hypospadias, Undescended Testis, Hydrocele, Ureteropelvic Junction Stenosis
- Trial name
- NCT02040389
- Testing
- Picture book, Standard preoperative education
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Shaare Zedek Medical Center
Rhinovirus, Congenital Heart Disease
'The Impact of Rhinovirus Infections in Paediatric Cardiac Surgery'
This is a prospective single- center observational study in the Leiden University Medical Center in approximately 250 children (<12 years) undergoing elective cardiac surgery, for congenital heart disease.
- Conditions
- Rhinovirus, Congenital Heart Disease, Respiratory Infections, Post-operative Complications
- Trial name
- RISK (NCT02438293)
- Testing
- rhinovirus diagnostics
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Leiden University
Congenital Heart Disease
Platelets or Fibrinogen as First-line Treatment for Bleeding During Pedatric Heart Surgery
The study aims to test whether platelet transfusion or fibrinogen concentrate is the most effective treatment of intraoperative bleeding, when performing open heart surgery with cardiopulmonary bypass on children with congenital…
- Trial name
- NCT04807621
- Testing
- Platelet transfusion, Fibrinogen concentrate
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Sahlgrenska University Hospital
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