Clinical trials: Neonatal Surgery
Postoperative Pain
Ultrasound Guided Penile Block vs Pudendal Block for Hypospadias
Pain after hypospadias surgery is a challenging issue to solve for anesthesists. Many different analgesia techniques were defined in literature for this purpose.
- Trial name
- NCT03496740
- Testing
- Penile Block, Pudendal Block, Bupivacaine (Block Drug)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kocaeli University
Myelomeningocele, Pregnancy
Evaluation of Hysterotomy Site After Open Fetal Surgery
This study is to review how the uterus heals after having open fetal surgery. Open fetal surgery causes a scar perhaps two: one from the open fetal surgery and a second from delivery by cesarean section; rarely, the same area of…
- Trial name
- Hysterotomy (NCT02493062)
- Testing
- Sonohysterogram
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- St. Louis University
Congenital Biliary Dilation
Treatment Strategy for Adult Congenital Biliary Dilation
The management of congenital biliary dilations (CBDs), including choledochal cysts, represents one of the most challenging areas in hepatobiliary surgery due to their potential implications for long-term morbidity and malignant…
- Trial name
- NCT07336576
- Testing
- hepatectomy、liver transplantation、hepaticojejunostomy
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Maxillary Hypoplasia
Orthodontic Retention on the Maxillary Stability After SARME Using Laser Scanner
The objective of this study was to evaluate the effect of the orthodontic retainer on transverse maxillary dental and skeletal stability after SARME.
- Trial name
- NCT01770782
- Testing
- Surgically Assisted Rapid Maxillary Expansion (SARME), Laser Scanner
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Max Domingues Pereira
Hypertrophic Cardiomyopathy, Coronary Artery Disease
Outcomes of Concomitant Bypass Surgery in Septal Myectomy
To investigate clinical characteristics and survival outcomes of patients with obstructive hypertrophic cardiomyopathy who underwent concomitant coronary artery bypass grafting during septal myectomy.
- Conditions
- Hypertrophic Cardiomyopathy, Coronary Artery Disease, Myocardial Bridging
- Trial name
- NCT06354413
- Testing
- CABG during myectomy
- Volunteers
- 320 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
C.Surgical Procedure; Cardiac, Blood Coagulation Disorders
Fibrinogen Concentrate In Children Cardiac Surgery 2
The purporse of this study is evaluate whether fibrinogen concentrate reduces postoperative bleeding in pediatric cardiac surgery with cardiopulmonary by-pass.
- Conditions
- C.Surgical Procedure; Cardiac, Blood Coagulation Disorders, Hypofibrinogenemia
- Trial name
- FiCCS2 (NCT03884725)
- Testing
- Fibrinogen Concentrate, control
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Filomena R B G Galas
Congenital Heart Disease, Airway Complication of Anesthesia
Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation
The aim of this study is to perform a pilot study investigating the first attempt intubation success rate differing between video laryngoscope nasotracheal intubation and direct laryngoscope nasotracheal intubation.
- Trial name
- NCT05902013
- Testing
- laryngoscopy
- Where
- Austria
- Volunteers
- 152 people
- Sponsor
- Medical University of Vienna
Cardiovascular Diseases, Heart Diseases
Comparison of Hematocrit Levels in Infant Heart Surgery
The purpose of this study is to compare the effects of diluted hematocrit (HCT) levels of 35% versus 25% during hypothermic cardiopulmonary bypass (CPB) in infants with d-transposition of the great arteries, a malformation of the…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Heart Defects, Congenital, Transposition of Great Vessels
- Trial name
- NCT00006183
- Testing
- Cardiopulmonary Bypass with Two Different Intra-Operative Hematocrits, Thoracic Surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Disease, Postoperative Care
Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach
The purpose of this clinical trial is to learn about the effects of a nursing support program designed for families of children aged 1 to 3 years who have undergone heart surgery.
- Conditions
- Congenital Heart Disease, Postoperative Care, Child Development, Roy Adaptation Model-based Nursing Empowerment Program
- Trial name
- NCT07575451
- Testing
- RAM-based Nursing Empowerment Program, Routine Care and Educational Booklet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Cardiac Surgery
Goal Directed Hemodynamic Management of Acute Heart Failure After Cardiac Surgery in Children
Goal directed therapy (GDT) utilises various monitoring techniques to assess cardiovascular performance and allows for timely interventions based on predetermined algorithms.
- Trial name
- NCT02617602
- Testing
- Goal directed therapy, Control
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Neuroendocrine Tumors, Von Hippel-Lindau Syndrome
Evaluation of 68Gallium-DOTATATE PET/CT for Detecting Neuroendocrine Tumors
Background: Neuroendocrine tumors (NETs) are rare but have been more common over the past decade. The only treatment for NETs is surgery, but most are found when they are too advanced for surgery.
- Conditions
- Neuroendocrine Tumors, Von Hippel-Lindau Syndrome, Hippel-Lindau Disease
- Trial name
- NCT01967537
- Testing
- 68Gallium DOTATATE, Radio-guided surgery
- Where
- United States
- Volunteers
- 341 people
- Sponsor
- National Cancer Institute (NCI)
Pregnant, Healthy Females, Healthy Male Newborns
Use of Existing Fibroblast Cells to Convert to Induced Pluripotent Stem Cells
Induced pluripotent stem cells potentially may be useful in the future as an unlimited source of cells for transplantation. The major goal of the project is to develop human iPS cells from existing lines of fibroblasts that were…
- Trial name
- NCT00801372
- Where
- Israel
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Velopharyngeal Insufficiency
Submucosa/Mucosal Pharyngeal Flap Trial
The investigators want to compare two different surgical techniques for the treatment of a condition called velopharyngeal dysfunction (VPD).
- Trial name
- NCT03187600
- Testing
- Mucosa/submucosa Pharyngeal Flap, Standard of Care Pharyngeal Flap
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Tourette's Syndrome
Optimising Anterior Pallidal Deep Brain Stimulation for Tourette's Syndrome
The motor tics associated with Tourette's syndrome may be reduced with deep brain stimulation of the anterior globus pallidus. The best area within this brain region and the best stimulation device settings are currently unknown.
- Trial name
- NCT02112253
- Testing
- Deep brain stimulator ventral electrode up to 2 mA, Deep brain stimulator ventral electrode up to 3 mA, Deep brain stimulator dorsal electrode up to 2 mA
- Where
- Australia
- Sponsor
- The University of Western Australia
Delirium, Congenital Heart Disease
An Intervention to Reduce Delirium After Cardiac Surgery
Patients that have cardiac surgery may suffer from unrecognized cerebral ischemia or loss of blood flow to the brain temporarily during surgery.
- Conditions
- Delirium, Congenital Heart Disease, Coronary Artery Disease, Heart Valve Disease
- Trial name
- NCT02587039
- Testing
- Remote ischemic pre-conditioning, Delirium Assessment
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Johns Hopkins University
Cardiac Surgery
HLA-DR Expression in Neonates After Cardiac Surgery Under Cardiopulmonary Bypass
The purpose of this study is to determine how monocyte HLA-DR and other markers of immune function change with time in neonates who underwent cardiac surgery with cardiopulmonary bypasss.
- Trial name
- IMMUNOPED (NCT03309839)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Diagnosis of Coarctation of the Aorta and VSD, Surgical Repair at CHOA
Surgical Outcomes in Pediatric Patients With Coarctation and VSD
Recently, a paper was published that compared outcomes of patients requiring repair of aortic coarctation and ventricular septal defect.
- Conditions
- Diagnosis of Coarctation of the Aorta and VSD, Surgical Repair at CHOA, Between January 1, 2002 and December 31, 2005
- Trial name
- NCT00327795
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Children's Healthcare of Atlanta
Tonsillitis, Sleep Disordered Breathing
Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery
Opioids are an important component of post-operative pain management among children, but are often prescribed in excess and rarely disposed of appropriately.
- Conditions
- Tonsillitis, Sleep Disordered Breathing, Hernia, Hydrocele
- Trial name
- NCT03575377
- Testing
- Disposal Aid
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Nationwide Children's Hospital
Newborn Morbidity, Oral Aversion
Sham Feeding Post-operative Infants
The purpose of this pilot study is to evaluate a feeding technique, sham feeding, to promote adequate oral skills in order to prevent oral aversion and/or poor oral skills due to the delay in oral feeds for surgical reasons.
- Conditions
- Newborn Morbidity, Oral Aversion, Gastroschisis, Bowel Obstruction
- Trial name
- NCT03350022
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Le Bonheur Children's Hospital
Complication of Renal Dialysis, End Stage Renal Disease
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatment delivered intraoperatively at the time of surgical creation of an…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS2 (NCT05425056)
- Testing
- Sirolimus
- Where
- 22 sites in United States, United Kingdom
- Volunteers
- 136 people
- Sponsor
- Vascular Therapies, Inc.
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