Clinical trials: Neonatal Surgery
Intracranial Arteriovenous Malformations
Nationwide Treatment Survey of Intracranial Arteriovenous Malformation in China
This register study will collect the treatment information of the intracranial arteriovenous malformation patients in China. We aim to understand the current treatment situation of the disease in China.
- Trial name
- NTSIAVMC (NCT01803685)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Dr. Yong Cao
Posto Perative Hepatocellular Carcinoma
Clinical Study of mRNA Vaccine in Patients With Liver Cancer After Operation
This is an open, one-arm study to evaluate the safety and efficacy of mRNA personalized tumor vaccine (tumor vaccine) encoding neonatal antigen in combination with Sintilimab injection for adjuvant prevention of postoperative…
- Trial name
- NCT05761717
- Testing
- Neoantigen mRNA Personalised Cancer vaccine in combination with Stintilimab I njection
- Volunteers
- 67 people
- Sponsor
- Shanghai Zhongshan Hospital
Hirschsprung Disease
Enhanced Recovery After Surgery In Hirschsprung Disease
The study is designed to determine if enhanced recovery after surgery (ERAS) principles could provide benefit for pediatric patients undergoing radical surgery for Hirschsprung's Disease (HD).
- Trial name
- ERASIHD (NCT02776176)
- Testing
- Enhanced Recovery After Surgery Program, Traditional Program
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Weibing Tang
Mandibular Hypoplasia
Applicability Clinic of Cement Portland Structural White in Endodontic Surgery
Thirty teeth twelve patients, two female and a male, who had persistent periradicular lesions were selected to participate in this study.
- Trial name
- NCT02474615
- Testing
- ENDODONTIC SURGERY
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Mesenteric Ischemia
Microcirculation During Extracorporeal Circulation
Digestive tract is supposed to be the motor of multiple organ failure. In ICU patients, mesenteric ischemia appears even when macrocirculatory parameters are controlled especially in our experience in patients coming in ICU after…
- Trial name
- CITRON4 (NCT01389947)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Gastrointestinal Disease
Neurodevelopmental Outcomes and Growth in Infants With Congenital Gastrointestinal Anomalies Requiring Neonatal Surgery
Infants with congenital gastrointestinal anomalies (CGIA) experience multiple physiologic stressors, including neonatal surgery, early in life during an essential time of growth and development.
- Trial name
- NOGINS (NCT04575649)
- Testing
- Gastrointestinal anomalies
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Developmental Dysplasia of the Hip (DDH)
Level of Iliopsoas Tenotomy in DDH Surgery
The goal of this clinical trial is to compare the postoperative clinical outcome of iliopsoas tenotomy in open reduction operation for developmental dysplasia of the hip.
- Trial name
- NCT06742749
- Testing
- Proximal level, Distal level
- Where
- Iraq
- Volunteers
- 54 people
- Sponsor
- University of Duhok
Pregnancy, Infertility
Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis
The primary research hypothesis is that microsurgical varicocelectomy will result in an increase in live birth in infertile couples where the male partner has a palpable varicocele and an abnormal semen analysis in comparison to…
- Trial name
- VIA (NCT00767338)
- Testing
- Timed intercourse, Microsurgical varicocelectomy, Intrauterine insemination
- Where
- 9 sites in United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Developmental Dysplasia of the Hip
Caudal Dexmedetomidine vs Ketamine for Postoperative Analgesia in Pediatric DDH Surgery
This study compares two medicines, Dexmedetomidine and Ketamine, added to caudal Bupivacaine to control pain after hip surgery in children.
- Trial name
- CDK-DDH (NCT07385352)
- Testing
- Dexmedetomidine, Ketamine, Bupivacaine
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Assiut University
Patient Safety, Organizational Change
Generalizing TESTPILOT to New Single Family Room NICUs
Complex service interventions are neither smooth nor easy in any transitioning healthcare facility. Simulations performed in the new environment reinforce patient safety by uncovering safety threats, enabling their correction…
- Trial name
- TESTPILOT (NCT02574104)
- Testing
- Simulate a functional NICU prior to moving patients
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Heart Defects, Congenital, Hypertension, Pulmonary
Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
This clinical trial will determine the safety and effectiveness of intravenous L-citrulline in children undergoing cardiopulmonary bypass during heart surgery.
- Trial name
- NCT00335244
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Incontinence, Urinary, Bladder Dysfunction
Bladder Neck Surgery in Children With Neurogenic Bladder
Surgical outcomes of bladder neck surgery in children with neurogenic bladder. Consequences on bladder voiding.
- Conditions
- Incontinence, Urinary, Bladder Dysfunction, Spina Bifida, Neurogenic Bladder
- Trial name
- CERPED (NCT05861011)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University of Lorraine
Patients Undergoing Surgery for Congenital Heart Disease
Incidence, Risk Factors, and Risk Model of Acute Kidney Injury in Pediatric Patients Who Undergoing Surgery for Congenital Heart Disease
Acute kidney injury (AKI) is a major complication after cardiac surgery and has been reported to be associated with adverse outcome.
- Trial name
- NCT02081235
- Testing
- surgery for congenital heart disease
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Samsung Medical Center
Ventricular Septal Defect
Bypass Clear Priming VSD Cardiopulmonary Bypass Circuit Reduce Bypass Associated Inflammation?
The purpose of this trial is to study if priming the pump used during cardiac surgery with non-blood fluids instead of donated blood products reduces the inflammation that occurs after heart surgery.
- Trial name
- NCT07393243
- Testing
- Clear priming of the bypass pump
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Seattle Children's Hospital
Transthyretin Amyloidosis, Carpal Tunnel Syndrome
Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surgery
This study will determine the prevalence of transthyretin amyloidosis in pathology of the transverse carpal ligament and cardiac involvement using natriuretic peptides, electrocardiography and echocardiography in patients…
- Trial name
- PRATHYC (NCT04611204)
- Testing
- Descriptive cohort
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Umbilical Hernia, Epigastric Hernia
Long-term Recurrence and Other Complications Requiring Surgery Following Primary Ventral Hernia Repair
Nationwide, registry based cohort studies on all complications requiring surgery following primary ventral hernia repair
- Trial name
- NCT06783036
- Where
- Denmark
- Volunteers
- 7,200 people
- Sponsor
- Bispebjerg Hospital
Hernia, Inguinal, Hernia, Femoral
Recover@Home Postoperative Follow-up Study
This proposal describes a human subjects research study evaluating mHealth Ambulatory Surgery with Follow-up Nurse (Recovery@Home), as an alternative postoperative care pathway for selected low-acuity surgical procedures in…
- Conditions
- Hernia, Inguinal, Hernia, Femoral, Hernia, Umbilical, Hernia, Ventral
- Trial name
- NCT07714343
- Testing
- Recovery@home
- Where
- 4 sites in Uganda
- Volunteers
- 194 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypospadias Repair Surgery
Urethral Mobilisation Versus Mathieu Technique for Repair of Distal Hypospadias
The aim of this research is to compare the surgical outcomes of urethral mobilization and the Mathieu technique in treating distal penile hypospadias.
- Trial name
- NCT06705699
- Testing
- Urethral mobilisation, Mathieu
- Volunteers
- 60 people
- Sponsor
- Assiut University
Intubation, Pediatric Surgery
Cuffed Versus Uncuffed Tracheal Tubes in PICU (PICU-BG-TT Study)
The CDC definition was used to identify patients with VAP and VAT. The CDC definition of VAP for infants < 1 y.o. and children > 1 or < 12 y.o. are based on clinical and X-ray criteria.
- Trial name
- PICU-BG-TT (NCT03129893)
- Testing
- Cuffed tracheal tubes
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)
The purpose of this research is to gather information on the safety and effectiveness of a new procedure called Fetoscopic Endoluminal Tracheal Occlusion (FETO).
- Conditions
- Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia, Pulmonary Artery Hypertension
- Trial name
- FETO (NCT03138863)
- Testing
- BALT GoldbBAL2 Detachable Balloon, Catheter System
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Rodrigo Ruano
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