Clinical trials: Neoplasms, Prostatic
Prostate Cancer
Perspectives About Online Information
The purpose of this research study is to understand the perspectives of U.S. adults on online information about prostate cancer.
- Trial name
- NCT07631858
- Testing
- Post (video) about prostate cancer, Post (text post) about prostate cancer, Survey
- Where
- United States
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Prostate Cancer
QLC5508 in Participants With Metastatic Prostate Cancer
This is a randomized, open-label, active-controlled, multicenter Phase III trial evaluating QLC5508 versus docetaxel in participants with metastatic castration-resistant prostate cancer (mCRPC) who have progressed after prior…
- Trial name
- NCT07632690
- Testing
- QLC5508, Docetaxel
- Volunteers
- 700 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Prostate Cancer
Safety, Pharmacokinetic and Proof-of-Concept Study of ARN-509 (Apalutamide) in Castration-Resistant Prostate Cancer (CRPC)
The purpose of this study is to assess the safety and activity of ARN-509 in men with advanced castration resistant prostate cancer.
- Trial name
- NCT01171898
- Testing
- ARN-509 (Phase 1), ARN-509 (Phase 2)
- Where
- 15 sites in United States
- Volunteers
- 127 people
- Sponsor
- Aragon Pharmaceuticals, Inc.
Breast Cancer, Hormone-resistant Prostate Cancer
Controlled Low Calorie Diet in Reducing Side Effects and Increasing Response to Chemotherapy in Patients With Breast or Prostate Cancer
This randomized phase II trial studies how well a controlled low calorie diet works in reducing side effects and increasing response to chemotherapy in patients with breast or prostate cancer.
- Conditions
- Breast Cancer, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer
- Trial name
- NCT01802346
- Testing
- dietary intervention, nutritional support, laboratory biomarker analysis
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- University of Southern California
Prostate Cancer, Low and Intermediate Risk Prostate Cancer
MRI Guided Focal Laser Ablation of Prostate Cancer
This clinical research study is designed to determine the ability of in bore MRI guided Focal Laser Ablation (MRgFLA) in patients with early stage carcinoma of prostate.
- Trial name
- MRgFLA (NCT03650595)
- Testing
- The TRANBERGCLS|Thermal Therapy
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- University Health Network, Toronto
Recurrent Prostate Cancer
Tumor Microenvironment Analysis of Prostate Cancer Metastasis
The purpose of this study is to collect prostate cancer tissue from males with metastatic prostate cancers in order to study the tumor microenvironment (TME), which is the area surrounding the tumor including cells, blood…
- Trial name
- NCT05304858
- Testing
- Biopsy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Columbia University
Prostate Cancer
Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer
This is a single-arm phase II prospective trials that is recruiting 100 participants. The study population that is being investigated are patients with localized high-risk or node-positive prostate cancer.
- Trial name
- MOB-RT (NCT05313815)
- Testing
- Moderate hypofractionated boost to the prostate with pelvic RT (external beam radiotherapy)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Feasibility of Day-surgery Management for Patients Undergoing Robotic Radical Prostatectomy: a Randomized Trial
To compare the day-surgery approach versus routine management in patients undergoing robotic radical prostatectomy, aimed at evaluating the feasibility of a one-day hospitalization regimen for robotic radical prostatectomy.
- Trial name
- NCT06891664
- Testing
- Day surgery regimen for patients, Ordinary management
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Regina Elena Cancer Institute
Prostate Cancer
A Multi-modal, Physician-centered Intervention to Improve Guideline-concordant Prostate Cancer Imaging
The primary aim of this study is to determine whether a multi-modal, physician-focused behavioral intervention can improve facility-level guideline-concordant utilization of prostate cancer staging imaging.
- Trial name
- NCT03445559
- Testing
- Clinical Order Check, Academic Detailing, Audit and Feedback
- Where
- 11 sites in United States
- Volunteers
- 58 people
- Sponsor
- VA Office of Research and Development
Prostate Cancer
Sacituzumab Govitecan in Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Second Generation AR-Directed Therapy
This study will investigate the safety and efficacy of Sacituzumab Govitecan in patients with metastatic castration-resistant prostate cancer progressing on second generation androgen receptor (AR) directed therapy (e.g.…
- Trial name
- NCT03725761
- Testing
- Sacituzumab Govitecan
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Prostate Adenocarcinoma, Prostate Cancer
Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
This phase II trial studies how well atezolizumab works alone or in combination with etrumadenant or tocilizumab in treating men with localized prostate cancer before radical prostatectomy.
- Conditions
- Prostate Adenocarcinoma, Prostate Cancer, Localized Prostate Cancer
- Trial name
- NCT03821246
- Testing
- Atezolizumab, Tocilizumab, Etrumadenant
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- David Oh
Prostate Cancer, Prostate Cancer Metastatic
An AI Platform Integrating Imaging Data and Models, Supporting Precision Care Through Prostate Cancer's Continuum
In Europe, prostate cancer (PCa) is the second most frequent type of cancer in men and the fifth most lethal. Current clinical practices, often leading to overdiagnosis and overtreatment of indolent tumors, suffer from lack of…
- Conditions
- Prostate Cancer, Prostate Cancer Metastatic, Prostate Cancer Recurrent, Prostate Cancer Aggressiveness
- Trial name
- NCT05384002
- Testing
- Magnetic Resonance Imaging
- Where
- Italy
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Prostate Cancer
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
The purpose of this post-marketing study is to further characterize the long-term outcome of known or potential risks of lutetium (177Lu) vipivotide tetraxetan also known as [177Lu]Lu-PSMA-617 or 177Lu-PSMA-617 and hereinafter…
- Trial name
- NCT05803941
- Testing
- AAA617
- Where
- 54 sites in United States, Austria and 9 more
- Volunteers
- 700 people
- Sponsor
- Novartis Pharmaceuticals
Advanced Metastatic Castration Resistant Prostate Cancer
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer
This is a Phase 1 and Phase 2 study to evaluate the safety and antitumor activity of INV-9956 in adult patients with advanced metastatic Castration Resistant Prostate Cancer.
- Trial name
- NCT06609005
- Testing
- INV-9956
- Where
- 22 sites in United States, China
- Volunteers
- 84 people
- Sponsor
- Shenzhen Ionova Life Sciences Co., Ltd.
Prostate CA
Trans and Non-binary Prostate-Specific Antigen Reference Interval Determination Study
The prostate specific antigen (PSA) blood test can help diagnose prostate problems, including cancer. The prostate is an organ in the pelvis. It is found in cisgender men, transgender (trans) women and some non-binary people.
- Trial name
- TransPRIDE (NCT06987045)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Castration-Resistant Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone
Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer
This randomized phase II trial studies how well enzalutamide with or without radium Ra 223 dichloride in treating patients with castration-resistant prostate cancer that has spread to other places in the body.
- Conditions
- Castration-Resistant Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone, Stage IV Prostate Cancer
- Trial name
- NCT03344211
- Testing
- Enzalutamide, Laboratory Biomarker Analysis, Radium Ra 223 Dichloride
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Prostate Cancer, Oligometastatic Disease
TERPS Trial for de Novo Oligometastic Prostate Cancer
This research is being done to see if we can improve the outcome of prostate cancer patients who present with metastatic lesions at initial diagnosis.
- Trial name
- NCT05223803
- Testing
- Prostate radiation (XRT), Systemic Therapy, Stereotactic ablative radiation therapy (SABR)
- Where
- 10 sites in United States
- Volunteers
- 122 people
- Sponsor
- University of Maryland, Baltimore
Prostate Cancer, Localized Prostate Carcinoma
PSMA-Guided Ablation of the Prostate
The goal of this phase 2 multicenter randomized controlled trial is to study the accuracy of second generation prostate specific membrane antigen (PSMA) positron emission tomography (PET; utilizing 18F-PSMA-1007) compared to…
- Trial name
- P-GAP (NCT06003556)
- Testing
- PSMA-1007 Positron Emission Tomography (PET) scan
- Where
- 4 sites in Canada
- Volunteers
- 138 people
- Sponsor
- University of Alberta
Metastatic Prostate Cancer
Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression
The goal of this clinical trial is to test the use of creatine monohydrate supplementation with resistance training to preserve muscle mass and help lessen prostate cancer progression.
- Trial name
- CREATINE-52 (NCT06112990)
- Testing
- creatine monohydrate, Home-based, telehealth
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Localized Prostate Carcinoma, Locally Advanced Prostate Carcinoma
Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors
This clinical trial evaluates a golf recreational exercise program for enhancing survivorship in underrepresented prostate cancer survivors.
- Conditions
- Localized Prostate Carcinoma, Locally Advanced Prostate Carcinoma, Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8, Stage II Prostate Cancer AJCC v8
- Trial name
- GREENS (NCT06500169)
- Testing
- Biospecimen Collection, Discussion, Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
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