Clinical trials: Nephropathy, open to volunteers
Chronic Kidney Diseases, Atrial Fibrillation
Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation
Objective: To study the efficacy and safety of apixaban as stroke prophylaxis in patients with chronic kidney disease (CKD) stage 5 and atrial fibrillation (AF) with or without dialysis treatment.
- Conditions
- Chronic Kidney Diseases, Atrial Fibrillation, Stroke, Intracerebral Hemorrhage
- Trial name
- SACK (NCT05679024)
- Testing
- Apixaban 2.5 milligram Oral Tablet
- Where
- 34 sites in Finland, Iceland and 2 more
- Volunteers
- 1,400 people
- Sponsor
- Region Stockholm
Renal Impairment
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal Disease
This study will be conducted to assess the safety and pharmacokinetics of INCB123667 when administered orally to adult participants with severe renal impairment or end stage renal disease.
- Trial name
- NCT07559396
- Testing
- INCB123667
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Incyte Corporation
Chronic Kidney Disease(CKD), Depression
Pharmacogenomics of Mood Disorder in Chronic Kidney Disease Patients
By using genetic information we could predict the prevalence of mood disorder and response to treatment.
- Trial name
- CKD (NCT06675396)
- Testing
- Antidepressants
- Volunteers
- 300 people
- Sponsor
- Wonju Severance Christian Hospital
Neoplasms, Kidney Neoplasms
Vorolanib in the Second-line Treatment of Patients With Unresectable or Metastatic Renal Cell Carcinoma
This is a multicenter real world study (RWS) initiated by the investigator. Eligible patients will be selected for treatment with second-line treatment including vorolanib and followed up.
- Conditions
- Neoplasms, Kidney Neoplasms, Urologic Neoplasms, Urogenital Neoplasms
- Trial name
- NCT06676527
- Testing
- Follow-up study of the treated cohort
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Jinling Hospital, China
Hypertension (HTN), CKD - Chronic Kidney Disease
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health
This study tests whether adding CHW support to usual nutrition care helps adults with type 2 diabetes, hypertension, or chronic kidney disease manage their diet and health.
- Conditions
- Hypertension (HTN), CKD - Chronic Kidney Disease, Cardio-Renal Syndrome, Food Insecurity
- Trial name
- INTEGRATE-CHW (NCT07918508)
- Testing
- INTEGRATE-CHW, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Florida International University
Nephrolithiasis
Tract Closure in PCNL
This is a prospective, randomized controlled trial evaluating the effect of a hemostatic agent on tract-related bleeding during percutaneous nephrolithotomy (PCNL).
- Trial name
- NCT07668817
- Testing
- Floseal, Surgicel, Surgiflo
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter
Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery
The goal of this clinical trial is to learn whether the addition of spinal analgesia leads to superior recovery in patients undergoing robotic-assisted laparoscopic upper urinary tract surgery under general anesthesia.
- Conditions
- Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter, Calculus of Kidney and Ureter, Ureter Cancer
- Trial name
- SMILe (NCT06349668)
- Testing
- spinal analgesia with morphine and bupivacaine, lidocaine infusion
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Hans Bahlmann
End-stage Renal Disease
Comparative Study of Prognosis and QOL Between APD-RPM and CAPD
This is an observational, multicenter, parallel control study, planning to enroll 750 eligible patients to receive automated peritoneal dialysis with remote patient management (APD-RPM) and continuous ambulatory peritoneal…
- Trial name
- NCT05738525
- Testing
- APD-RPM
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Chinese PLA General Hospital
Noradrenaline
Prophylactic Norepinephrine for Prevention of Acute Kidney Injury in Living-Donor Liver Transplantation
goal-directed fluid therapy has demonstrated benefits on postoperative organ function, vasopressor support with norepinephrine is commonly employed to maintain perfusion pressure, though its renal impact in this setting remains…
- Trial name
- NE AKI in LDLT (NCT07885657)
- Testing
- Norepinephrine started prophylactically immediately post induction of general anesthesia, Norepinephrine infusion will only initiated if mean arterial pressure <65 mmHg despite preload optimization (stroke volume variation <12%) or if systemic vascular resistance <800 dynes•s/cm⁵
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Mansoura University
Hypertension, Type 2 Diabetes Mellitus
Nanshan Elderly Cohort Study
Objective: The Nanshan Elderly Cohort Study (NECS) aims to investigate the nutritional, as well as other environmental and genetic factors of chronic diseases, such as cardio-metabolic diseases.
- Conditions
- Hypertension, Type 2 Diabetes Mellitus, Cardiovascular Diseases, Stroke
- Trial name
- NECS (NCT03569735)
- Where
- 2 sites in China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cardiac Rhythm Disorders, Urological Disorders
Product Surveillance Registry
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products.
- Conditions
- Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
- Trial name
- PSR (NCT01524276)
- Where
- 402 sites in United States, Argentina and 39 more
- Volunteers
- 100,000 people
- Sponsor
- Medtronic
Chronic Kidney Disease Stage 4
Effect of Henagliflozin on Renal Outcomes in Non-dialysis Patients With Advanced Chronic Kidney Disease : A Multicenter Prospective, Randomized Controlled Trial（HERO -aCKD）
This is a multicenter, prospective, randomized, controlled study that will enroll approximately 429 subjects. The screening period will last 4-8 weeks.
- Trial name
- NCT07027774
- Testing
- Henagliflozin 5 mg Group, Henagliflozin 10 mg Group, Conventional therapy group
- Volunteers
- 429 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Renal Cell Carcinoma (RCC), Renal Pelvic Urothelial Carcinoma
18F-N230A PET/CT Imaging of Nectin-4 Expression in Renal Tumors
Renal cell carcinoma and renal pelvic urothelial carcinoma are common malignant tumors of the urinary system. Accurate preoperative differentiation between these tumor types is important for treatment planning, while conventional…
- Trial name
- NCT07875959
- Testing
- 18F-N230A
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Renal Cell Carcinoma
Delving Into Participation Trends in Renal Cell Carcinoma Studies
The study seeks to delve into the firsthand experiences of patients diagnosed with renal cell carcinoma who partake in a separate clinical study featuring a specific medical intervention.
- Trial name
- NCT06093568
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Anesthesia, Spinal Aneshtesia
Renal Functions in Preeclamptic Pregnant Women Using Neutrophil Gelatinase-associated Lipocalin (NGAL) and Standard Renal Function Tests
Acute kidney injury (AKI) is a significant postoperative complication. Risk factors for AKI include impaired renal perfusion, decreased functional renal reserve, as well as advanced age, peripheral arterial disease, diabetes…
- Conditions
- Anesthesia, Spinal Aneshtesia, Acute Kidney Failure, Spinal Anesthesia Induced Hypotension
- Trial name
- NCT07015359
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Nihan Aydin Guzey
Chronic Kidney Diseases
Uremic Toxins and Outcomes in Chronic Kidney Disease
The aim of this cohort study is: To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality…
- Trial name
- NCT03711617
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
End Stage Kidney Disease
Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants
The purpose of this study is to evaluate the safety and efficacy of the Moda-flx Hemodialysis System™ when used Under Professional Care Settings by trained individuals and At Home by trained Participants and Care Partners
- Trial name
- NCT06613568
- Testing
- Moda-flx Hemodialysis System™
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Diality Inc.
Renal Cancer, Renal Cell Carcinoma
National PROspective Infrastructure for Renal Cell Carcinoma (PRO-RCC)
PRO-RCC is a nationwide long-term cohort for the collection of real-world clinical data, patient reported outcome measures (PROMs) and patient reported experience measures (PREMs) that provides an infrastructure for observational…
- Conditions
- Renal Cancer, Renal Cell Carcinoma, Renal Cell Cancer Metastatic
- Trial name
- PRO-RCC (NCT05326620)
- Where
- 27 sites in Netherlands
- Volunteers
- 2,000 people
- Sponsor
- PROspective Renal Cancer Cohort Foundation
Diabetes, End Stage Renal Disease
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultrasound when used under a protocol of biweekly use for assessing fistula…
- Trial name
- MAFASA (NCT06190717)
- Testing
- EchoMark/EchoSure, Standard of Care
- Where
- 23 sites in United States
- Volunteers
- 304 people
- Sponsor
- Sonavex, Inc.
Advanced Ovarian Carcinoma, Advanced Renal Cell Carcinoma
First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients With Selected Advanced and/or Metastatic Solid Tumours
The goal of this clinical trial is to learn if the OATD-02 administration (orally) in monotherapy is safe and has the pharmacodynamic potential to restore and enhance tumour responses to immunotherapy through increased arginine…
- Conditions
- Advanced Ovarian Carcinoma, Advanced Renal Cell Carcinoma, Advanced Pancreatic Carcinoma, Advanced Colorectal Carcinoma
- Trial name
- NCT05759923
- Testing
- OATD-02
- Where
- 3 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Molecure S.A.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.