Clinical trials: Nerve Block/Methods
Burns
Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients
The purpose of this study is to determine whether either a peripheral nerve block under ultrasound (u/s) guidance of the lateral femoral cutaneous nerve (LFCN), versus an u/s guided block of the nerve followed by continuous…
- Trial name
- NCT01500655
- Testing
- Regional nerve block, Catheter
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts General Hospital
Pulmonary Dysfunction, Median Sternotomy Recovery
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
Background and Rationale: Open-heart surgery via a median sternotomy is associated with severe acute postoperative pain. This pain can impair a patient's ability to take deep breaths and cough effectively which increases the risk…
- Conditions
- Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
- Trial name
- FROST-STERN (NCT07637370)
- Testing
- Intercostal Nerve Cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Supratentorial Tumors
Comparison of Systemic Opioid (Morphine) and Pre-Incision Bilateral Scalp Nerve Block for Pain Management in Craniotomy Patients
The goal of this randomized controlled clinical trial is to compare the effectiveness of systemic opioids versus pre-incision bilateral scalp nerve block in managing intraoperative noxious stimuli and postoperative pain in adult…
- Trial name
- NCT07425678
- Testing
- Scalp nerve block, Morphine, Lidocaine
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Aga Khan University
Analgesia Assessment, Above Knee Amputation
The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .
The aim of this study is to compare the analgesic efficacy and safety of dexmedetomidine versus fentanyl as adjuvants to bupivacaine in ultrasound-guided combined supra-inguinal fascia iliaca and proximal sciatic nerve blocks…
- Conditions
- Analgesia Assessment, Above Knee Amputation, Fentanyl vs Dexmedetomidine
- Trial name
- NCT07640516
- Testing
- Dexmedetomidine, Fentanyl (as Citrate)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Kasr El Aini Hospital
Airway Obstruction, Vocal Cord Paralysis
Total Versus Partial Arytenoidectomy in Bilateral Vocal Fold Paralysis
Total arytenoidectomy is claimed to increase risk of aspiration and cause more voice loss than other operations performed for bilateral vocal fold paralysis (BVFP). However, objective evidence for such conclusion is lacking.
- Trial name
- NCT01824849
- Testing
- Total arytenoidectomy, Partial arytenoidectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Distal Radius Fracture
Comparison of Clinical Outcomes of Distal Radius Fractures Treated Surgically With WALANT and Peripheral Nerve Block
WALANT anesthesia technique has been frequently preferred in hand and upper extremity surgery in recent years. WALANT technique; It stands out with its advantages such as lack of pre-operative anesthesia preparation process…
- Trial name
- NCT05832021
- Testing
- Open reduction and internal fixation (under WALANT), Open reduction and internal fixation (under peripheral nerve block)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Anesthesia, Local, Nerve Block
Lateral Sagittal vs Costoclavicular Approach for Ultrasound-Guided Infraclavicular Block
An ultrasound-guided infraclavicular block performed with the costoclavicular (CC) approach and the lateral sagittal (LS) approach will be compared in patients scheduled for forearm and hand surgery.
- Conditions
- Anesthesia, Local, Nerve Block, Brachial Plexus Block
- Trial name
- NCT04356521
- Testing
- Lateral Sagittal Approach, Costoclavicular Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Osteoarthritis
The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)
Total knee replacement is associated with severe post-operative pain. The purpose of this study is to compare two methods of treatment for pain control following Total Knee Replacement with an accelerated physical therapy…
- Trial name
- ACB PAI (NCT02292082)
- Testing
- Bupivacaine, Morphine, Methylprednisolone
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Hospital for Special Surgery, New York
Arthroscopic Shoulder Surgery
Effects of Technique on the Local Anesthetic Dose Required for Interscalene Brachial Plexus Block
Interscalene brachial plexus block (ISBPB) is a common nerve block given to patients who are undergoing shoulder surgery. This block has a low, but still significant, rate of complications.
- Trial name
- NCT00731146
- Testing
- Ultrasound Minimum Effective Anesthetic Volume, Nerve Stimulator Minimum Effective Anesthetic Volume
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Orthopedic Surgical Procedures, Postoperative Pain
Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), leads to longer anesthesia and analgesia of the leg.
- Trial name
- NCT01981291
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Parma
Tooth Extraction Status Nos, Anesthesia, Local
Efficacy and Safety of Administration of Different Doses of 4% Articaine.
The goal of this triple-blind randomized clinical trial is to compare the efficacy and safety of administering one cartridge (1.8 mL) versus two cartridges of articaine 4% with epinephrine 1:100,000 for lower third molar…
- Trial name
- NCT06644950
- Testing
- Efficacy and safety of administering 1 or two cartridges of anesthesia
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Augmented Reality, Virtual Reality
Augmented Reality/Virtual Reality (AR/VR) for Ultrasound-guided Medical Procedures
The study seeks to assess the efficacy of incorporating augmented reality (AR) or virtual reality (VR) technology into ultrasound-guided medical procedures such as regional anesthesia and line placement.
- Trial name
- NCT06550193
- Testing
- Ultrasound-guided procedure using AR/VR technology
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Urinary Bladder Neoplasms, Transurethral Resection
Ultrasound-Guided ONB for Transurethral Procedures - Interadductor Approach
Obturator nerve block is an effective method to prevent adductor muscles contraction during transurethral resection of bladder tumour localized on the lateral wall.
- Conditions
- Urinary Bladder Neoplasms, Transurethral Resection, Nerve Block
- Trial name
- NCT02696733
- Testing
- Ultrasound, lidocaine 2%, 0.9% Natrium Chloratum with a 2nd generation cephalosporin
- Where
- 2 sites in Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Anesthesia
Combination of Serratus Anterior and Pectoral Nerve Blocks (PECS II) as Main Anesthetic Method in Breast Cancer Surgery
Aim of this study is to determine the success of combined serratus anterior and PECS-2 block as the main anesthetic method in breast cancer surgery and also to investigate the patient acceptability of this combination and its…
- Trial name
- NCT05427292
- Testing
- serratus anterior block and PECs II block combination
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Samsun University
Procedural Pain
A Combined 2% Lidocaine Anesthetic Technique for Mandibular Molar Procedures Without Inferior Alveolar Nerve Block
This prospective single-arm pilot study evaluated the clinical effectiveness of a combined local anesthetic technique using 2% lidocaine with 1:100,000 epinephrine for dental procedures involving mandibular molars.
- Trial name
- NCT07771452
- Testing
- Lidocaine 2% with 1:100 000 epinephrine
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Herat University
Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand
USG Brachial Plexus Block for Upper Extremity Surgery
Ultrasound-guided (USG) brachial plexus (BP) block efficacy at the Supraclavicular (SCL), Lateral- Infraclavicular (LIC) and Axillary (AX) level: Randomized, observer-blinded study of the single-penetration…
- Conditions
- Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand, Injuries to the Wrist, Hand and Fingers (S60-S69), Ganglion Cysts
- Trial name
- NCT01993290
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Jens Borglum Neimann
Analgesia
Study Comparing a Nerve Block With Spinal Opiate to Provide Pain Relief for Hip Replacement Surgery
Pain control after hip replacement surgery is important to ensure patient comfort, allow mobilisation, and aid recovery. The investigators propose a simple and pragmatic study comparing two different anaesthetic techniques in the…
- Trial name
- NCT01217294
- Testing
- ultrasound guided fascia iliaca block, spinal morphine
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Rachel Kearns
Local Wound Infiltration, Erector Spina Plan Block
Ultrasound-guided Erector Spinae Plane Block Versus Local Wound Infiltration in Breast Conservative Surgery
Abstract Background: Postoperative pain management is a crucial component of patient care following breast conservative surgery.
- Conditions
- Local Wound Infiltration, Erector Spina Plan Block, Nerve Block/Methods, Post Operative Analgesia
- Trial name
- NCT07301840
- Testing
- Erector Spinae Plane Block, Local Wound Infiltration
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Dental Anaesthesia
Intraosseous Anesthesia Versus Mandibular Nerve Block in Children
The aim of the current study is to compare a new computerized intra-osseous injection system to the conventional inferior alveolar nerve block in children
- Trial name
- NCT05193487
- Testing
- inferior alveolar nerve block, intra-osseous mandibular anaesthesia
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Mastectomy, Breast Neoplasms
Ultrasound vs. Predetermined Distance Techniques for Paravertebral Nerve Block in Patients Having Breast Surgery
The purpose of this study is to compare ultrasound and predetermined distance techniques for finding the paravertebral space to inject the local anesthetic (numbing medicine) when you are given anesthesia for surgery.
- Trial name
- NCT01217593
- Testing
- ultrasound, predetermined distance
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ochsner Health System