Clinical trials: Nerve Block Assessment
Surgery, Upper Extremity
Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery
The purpose of this study is to learn about the effectiveness of different pain control options after hand and wrist surgery, specifically Ketorolac, Tylenol, and a regional nerve block.
- Trial name
- NCT07773155
- Testing
- Toradol, Oxycodone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Regional Anesthesia, Horner Syndrome
Cerebral Blood Flow Evaluation With Trancranial Doppler After Interscalene Nerve Block
The purpose of this study is to assess cerebral blood flow velocity (CBFV) following regional anesthesia for shoulder surgery. The results of this study will help to further understand the physiologic effect of the interscalene…
- Conditions
- Regional Anesthesia, Horner Syndrome, Cerebral Blood Flow
- Trial name
- CBF-TCD (NCT04642612)
- Testing
- TCD Measurement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anesthesia, Upper Extremity Injury
Clinical Evaluation of the Ultrasound-Guided Retroclavicular Brachial Plexus Block
The primary objective of this prospective, descriptive study is to evaluate the success rate of the retroclavicular brachial plexus block and catheter placement in 60 adult patients undergoing hand, wrist, or forearm surgery.
- Trial name
- NCT01605929
- Testing
- Retroclavicular Brachial Plexus Block and Catheter Insertion
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Catastrophizing Pain
Personalizing Preprocedural Sedation for Regional Anesthesia
This is a prospective, randomized study in patients who receive a nerve block prior to surgery. The aim is to investigate whether individual differences in psychosocial and pain profiles may play a role in how patients experience…
- Trial name
- NCT05579509
- Testing
- Midazolam and Fentanyl, Educational Reassurance
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Lower Extremity Surgery, Bunion
Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries
This is a Phase 3, multicenter, randomized, double blinded, active controlled study in approximately 120 subjects undergoing lower extremity surgeries.
- Conditions
- Lower Extremity Surgery, Bunion, Metatarsophalangeal Fushion, Midfoot Fusion
- Trial name
- STRIDE (NCT04518462)
- Testing
- Exparel, Bupivacaine Hydrochloride
- Where
- 5 sites in United States
- Volunteers
- 121 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Locoregional Analgesia in Breast Surgery
Double-blind Study to Assess effectIveness of Pectoral Nerves Block After Breast Surgery on Piritramide Consumption
The aims of this study is to compare the effectiveness of pecs block associated to a general anesthesia in terms of Piritramide consumption compared with a general anaesthesia alone and the chronic pain incidence in patients that…
- Trial name
- DESIGN (NCT02655965)
- Testing
- Ropivacaine, Clonidine, Sodium Chloride
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Jules Bordet Institute
Femoral Neck Fractures, Lumbosacral Plexus
Lumbar Plexus Block Application in Ultrasound-guided Shamrock Method
The more effective use of ultrasound in regional anaesthesia techniques has made different block applications possible. Lumbar plexus block is also used for post-operative analgesia and surgical anaesthesia.
- Conditions
- Femoral Neck Fractures, Lumbosacral Plexus, Nerve Block
- Trial name
- NCT06088368
- Testing
- in-plane needle guidance, out-of-plane needle guidance
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Post-operative Pain, Irreversible Pulpitis
Relationship of Eye Colour With Anesthetic Success and Post-Operative Pain
Current evidence indicates that some phenotypic characteristics, such as eye or hair color, might be associated with the experience of pain.
- Trial name
- NCT06206304
- Testing
- Root canal therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Bunionectomy, Hallux Valgus
Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy
The study is conducted sequentially in two parts. Part A: The purpose is to obtain information on pharmacokinetic (PK) profile, pharmacodynamics (PD), efficacy, safety, and to assess the performance of 266 mg EXPAREL vs 133 mg…
- Trial name
- NCT05157841
- Testing
- Bupivacaine liposome injectable suspension 266 mg, Bupivacaine HCl, Bupivacaine liposome injectable suspension 133 mg
- Where
- 7 sites in United States
- Volunteers
- 185 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Melanoma
A Phase I/II Trial to Evaluate a Peptide Vaccine Plus Ipilimumab in Patients With Melanoma
This study evaluates whether it is safe to administer a peptide vaccine with ipilimumab. This study will also evaluate the effects of the combination of the peptide vaccine and ipilimumab on the immune system.
- Trial name
- Mel62; 6PAC (NCT02385669)
- Testing
- Ipilimumab, 6MHP
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Craig L Slingluff, Jr
Regional Anaesthesia, Emergency Medicine
Comparative Evaluation of Ultrasound-Guided Femoral Nerve Block Training With Low-Fidelity Low-Cost Simulation Model Among Junior Doctors in Department of Emergency Medicine USM.
To study the effectiveness of low-fidelity ultrasound-guided femoral nerve block training interventions score in knowledge and skills performance among junior doctors in the Department of Emergency Medicine Universiti Sains…
- Trial name
- NCT07604506
- Testing
- Low-fidelity ultrasound-guided femoral nerve block simulation training
- Where
- Malaysia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Ultrasound Imaging of Anatomical Structures
Clinical Performance Study: Evaluate Scanning & Interpretation Performance With & Without ScanNav Anatomy PNB
This is a single-centre, randomised, interventional prospective cohort study to be undertaken at offices of Intelligent Ultrasound Limited in Cardiff, United Kingdom.
- Trial name
- PNB (NCT05156099)
- Testing
- Ultrasound Scanning, Ultrasound Scanning - 2 months later
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- IntelligentUltrasound Limited
Shoulder Surgery, Regional Anesthesia Morbidity
Intraoperative Pain and Quality of Surgical Block During Shoulder Surgery Assessed by NOL Index
Postoperative analgesia for shoulder surgery is typically achieved by providing an interscalene brachial plexus block. However, a very common side effect of this block is hemi-diaphragmatic paralysis, a state which may not be…
- Trial name
- NCT04015284
- Testing
- Suprascapular Nerve Block + Posterior Cord Block, Interscalene Brachial Plexus Block
- Where
- Canada
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Breast Cancer, Anesthesia
Pain Control in Breast Surgery: Analgesia, Opioid Consumption and Inflammatory Response Evaluation
The serratus anterior muscle plane (SAM) block associated with pectoral nerve block type I (PEC I) may be a safe and effective alternative for the intraoperative of breast surgery, since there is evidence of pain reduction.
- Trial name
- NCT02647385
- Testing
- Block with lidocaine for SAM and PEC I block
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital Sirio-Libanes
Arthroplasty, Replacement, Knee, Nerve Block
Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA
The purpose of this study is to determine if patients undergoing a Total Knee Arthroplasty who receive a single shot Adductor Canal nerve block and local infiltration will have improved functional outcomes compared to individuals…
- Trial name
- ACB (NCT02218814)
- Testing
- Adductor Canal Block, Bupivacaine, Femoral Nerve Block, Bupivacaine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- George Macrinici
Anterior Cruciate Ligament Injuries, Postoperative Pain
Postoperative Analgesic Efficacy of ACB+iPACK vs FTB+Selective Tibial+Obturator Blocks in ACL Reconstruction
This prospective, comparative study aims to evaluate the postoperative analgesic efficacy of ultrasound-guided Adductor Canal Block (ACB) combined with iPACK block versus Femoral Triangle Block (FTB) combined with selective…
- Trial name
- ACL-Analgesia (NCT07702552)
- Testing
- Ultrasound-guided Adductor Canal Block (ACB), Ultrasound-guided iPACK block, Ultrasound-guided Femoral Triangle Block (FTB)
- Volunteers
- 100 people
- Sponsor
- Da Nang Hospital
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Whiplash Injuries
Is Chronic Whiplash-associated Pain of Neurogenic Origin?
The purpose of this study is to compare the effects of neurolysis with the effects of a exercise program on pain and other symptoms in individuals with chronic whiplash (WAD II-III).
- Trial name
- NCT02692937
- Testing
- Neurolysis, Traditional neck-specific exercise program
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Postoperative Pain
Evaluation the Effect of Using Preoperative Ibuprofen Versus Low Level Laser Therapy on Inferior Alveolar Nerve Block
Acute apical periodontitis (AAP) is an inflammatory condition of the periapical tissues of the periodontium, usually resulting from irreversible pulpitis and pulpal necrosis.
- Trial name
- NCT05479175
- Testing
- Ibuprofen, Diode laser, Nonactive Diode laser
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pain, Postoperative, Pain
Evaluation of Supraclavicular, Suprascapular, and Interscalene Nerve Blocks for Outpatient Shoulder Surgery
The aim of this study is to assess analgesic efficacy of a supraclavicular nerve block, suprascapular nerve block, or interscalene nerve block in a population undergoing shoulder arthroscopy with rotator cuff repair.
- Conditions
- Pain, Postoperative, Pain, Shoulder Joint, Pathologic Processes
- Trial name
- NCT02287142
- Testing
- Brachial plexus nerve block
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- Benaroya Research Institute