Clinical trials: Nerve Block Assessment
Femoral Neck Fractures, Blood Loss, Surgical
Effect of Regional Anesthesia Techniques on Perioperative Blood Loss in Femoral Neck Fracture Surgery
This retrospective observational study evaluates the effect of different regional anesthesia techniques on perioperative blood loss in patients undergoing femoral neck fracture surgery.
- Conditions
- Femoral Neck Fractures, Blood Loss, Surgical, Postoperative Pain
- Trial name
- NCT07702084
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anesthesia, Local
The CIA Score: a Learner's Tool
The goal of this project is to use a previously described scoring system - the CIA system - as a teaching tool to help learners assess the bleeding risk of peripheral nerve blocks.
- Trial name
- NCT05153265
- Testing
- Survey
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population
The goal of this randomized clinical trial is to determine if single-shot ropivacaine peripheral nerve blocks (PNB - perineural injections) for anterior cruciate ligament (ACL) reconstruction procedures in pediatric orthopaedic…
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559137
- Testing
- Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Pain, Postoperative
Postoperative Analgesic Effects of Infraorbital Nerve Block in Cleft Palate Surgery
Cleft palate repair is a common surgery in children.. As such children with cleft palate tend to have a compromised airway due to associated congenital anomalies like Pierre Robin syndrome, Treacher Collins syndrome etc.
- Trial name
- NCT04212611
- Testing
- INFRA ORBITAL BLOCK
- Where
- India
- Volunteers
- 80 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Spontaneous Breathing, Laryngomicrosurgery
Evaluation of the Feasibility and Safety of Laryngoscopic Microsurgery Under Non-intubation Anesthesia
Nonintubated anesthesia applied in combination with high-flow nasal oxygen (HFNO) is an alternative strategy for laryngeal microsurgery (LMS).
- Conditions
- Spontaneous Breathing, Laryngomicrosurgery, Superior Laryngeal Nerve Block
- Trial name
- NCT05420649
- Testing
- Non-intubated Laryngomicrosurgery
- Where
- Taiwan
- Volunteers
- 49 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Anesthesia, Regional Anesthesia Morbidity
Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection
INTRODUCTION: The axillary lymphadenectomy procedure is known to be associated with late postoperative complications, such as chronic pain and changes in shoulder mobility.
- Conditions
- Anesthesia, Regional Anesthesia Morbidity, Axillary Metastases, Nerve Block
- Trial name
- NCT03740815
- Testing
- Serratus plane block, Axillary dissection, Intravenous sedation
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Pain, Postoperative, Pain Management
Bilateral Serratus Intercostal Plane Block for Myocardial Revascularization (SERRINT)
Two-parallel arm, double-blind, individually randomized controlled trial. Primary endpoint: Fentanyl consumption in the first 48 postoperative hours.
- Conditions
- Pain, Postoperative, Pain Management, Analgesia, Patient-Controlled, Nerve Block
- Trial name
- SERRINT (NCT03813225)
- Testing
- Bilateral serratus Intercostal plane Block
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación Cardiovascular de Colombia
Knee Osteoarthritis
Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves
Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs.
- Trial name
- NCT05340166
- Testing
- Genicular nerve radiofrequency neurolysis, Genicular nerve chemical neurolysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Irreversible Pulpitis
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis
This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with…
- Trial name
- NCT04157036
- Testing
- Ibuprofen, Methylprednisolone
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Hernia, Inguinal, Flat Foot
The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population
Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial to evaluate the efficacy and safety of local anesthetic Chloroprocaine at two different concentrations ( at 1% and 2%) in a pediatric…
- Trial name
- NCT03918798
- Testing
- Chloroprocaine 1% Injectable Solution, Chloroprocaine 2% Injectable Solution
- Where
- 9 sites in Italy, Spain
- Volunteers
- 164 people
- Sponsor
- Sintetica SA
Nerve Block, Lumbar Plexus
Evaluation of Lumbar Plexus Block Success With Near Infrared Spectroscopy (NIRS)
Tests such as the pin-prick test, cold application or the Bromage scale are currently used to measure the success of nerve blocks and are considered subjective assessments as they require verbal consent from the patient.
- Conditions
- Nerve Block, Lumbar Plexus, Near Infrared Spectroscopy
- Trial name
- NCT06126133
- Testing
- Near Infrared Spectroscopy
- Volunteers
- 40 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Postoperative Pain Management, Postoperative Pain
Postoperative Analgesic Efficacy of Modified TAPA and QL Blocks in Laparoscopic Cholecystectomies
Comparison of Postoperative Analgesic Effects of M-TAPA and Anterior Quadratus Lumborum Blocks in Laparoscopic Cholecystectomies.
- Conditions
- Postoperative Pain Management, Postoperative Pain, Analgesia, Nerve Blocks
- Trial name
- NCT06540586
- Testing
- anterior Quadratus lumborum block, M-TAPA BLOCK
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Analgesia
Assessment of the Effect of Age on Duration of Analgesia From Single-shot Femoral Nerve Blocks
Cohort study to examine the effect of age on duration of analgesia in patients receiving single-shot femoral nerve block prior to surgery, by postoperative phone follow-up questionnaire.
- Trial name
- NCT04495413
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Nerve Blocks, Medical Education, Simulation, Crisis Resource Management
Ultrasound-guided Nerve Block Training Model and Evaluation Method
The aim of this study is to assess emergency medicine physician knowledge and technical skill in performance of ultrasound-guided serratus anterior nerve block in a low-fidelity simulation model workshop and to determine the…
- Conditions
- Nerve Blocks, Medical Education, Simulation, Crisis Resource Management, Medical Education in Emergency Ultrasound
- Trial name
- NCT06219005
- Testing
- ultrasound education and simulation workshop
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Duke University
Unmethylated Glioblastoma
Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma
This is a single institution, open-label, multi-arm, phase I study assessing the safety and immunogenicity of a personalized neoantigen-based personalized DNA vaccine combined with PD-1 blockade therapy in subjects with newly…
- Trial name
- NCT05743595
- Testing
- Personalized Neoantigen DNA vaccine, Retifanlimab, TDS-IM v 2.0 electroporation device
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Melanoma
Safety Study of a Helper Peptide Vaccine Plus Pembrolizumab
This study evaluates whether it is safe to administer a peptide vaccine in combination with pembrolizumab. This study will also evaluate the effects of the combination of the peptide vaccine and pembrolizumab on the immune…
- Trial name
- Mel64 (NCT02515227)
- Testing
- 6MHP, Pembrolizumab
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Craig L Slingluff, Jr
Degenerative Joint Disease of the Ankle
A Pilot Study to Evaluate the Contribution of the Saphenous Nerve in Ankle Pain of Patients With Degenerative Joint Disease of the Ankle
To assess the pain scores before and after saphenous nerve block placement in patients with degenerative joint disease of the ankle
- Trial name
- NCT01716650
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Pudendal Neuralgia Pudendal Nerve Entrapment Chronic Pelvic Pain
Pudendal Nerve Block With Articaine and Triamcinolone for Pudendal Neuralgia
This study is testing whether an injection of local anesthetic (articaine) combined with a steroid (triamcinolone), placed near the pudendal nerve under ultrasound guidance, can reduce pain in people with pudendal neuralgia - a…
- Trial name
- NCT07828574
- Testing
- Articaine and triamcinolone
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Irkutsk State Medical University
Postoperative Pain Management in Total Knee Arthroplasty
Efficacy of an AFCN Proxy Block in Post-TKA Multimodal Pain Management
This randomized controlled trial evaluates the additive effect of Supra-Sartorial Subcutaneous Infiltration (SSSI) when performed in combination with intermittent adductor canal block (iACB) and posterior capsule local…
- Trial name
- NCT07191964
- Testing
- Supra-Sartorial Subcutaneous Infiltration (SSSI), intermittent adductor canal block (iACB), posterior capsule local infiltration analgesia (PC-LIA)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Medical University WanFang Hospital