Clinical trials: Nerve Block Duration
Regional Block for Pain Control, Supraclavicular Block
Duration of Analgesic Effect for Ultrasound Guided Supraclavicular Blocks With the Addition of Buprenorphine to Local Anesthetic Solution
The patients included will be those who have already agreed to have a brachial plexus nerve block for surgery. A flip of the coin will decide who gets and additive called buprenorphine in their block or not.
- Conditions
- Regional Block for Pain Control, Supraclavicular Block, Ultrasound Guided Block, Block Additive
- Trial name
- NCT01583179
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Wisconsin, Madison
Pain, Total Knee Arthroplasty
Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic
This is a Randomized Double blinded controlled trial on the effect of adding dexamethasone to Ropivacaine on the duration of pain relief for ultrasound guided femoral, obturator and popliteal block after total knee replacement…
- Trial name
- NCT01511211
- Testing
- Dexamethasone, Ropivacaine
- Where
- United States
- Sponsor
- University of New Mexico
Pain, Postoperative, Anesthesia, Local
Comparison of Ultrasound-guided Brachial Plexus Blocks and Selective Distal Blocks in Terms of Anesthesia
Ultrasound-guided brachial plexus blocks (infraclavicular, axillary) can be applied as the main anesthetic method in hand and wrist surgeries, as well as single or combination block applications of the median, radial and ulnar…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Patient Satisfaction
- Trial name
- NCT05656625
- Testing
- descriptive
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Samsun University
Low Back Pain
Comparative Study of Real-time Ultrasound-CT Fusion Imaging and Ultrasound-guided Selective Lumbar Nerve Root Block
The study is aimed at patients with low back and leg pain. The experimental group of patients underwent selective lumbar nerve root block puncture under real-time ultrasound-CT fusion imaging by sonographers, and the control…
- Trial name
- NCT04964804
- Testing
- real-time ultrasound-CT fusion imaging, ultrasound alone
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Post Operative Analgesia, Regional Anesthesia
Does Interneural Local Anesthetic Spread at the Site of Sciatic Nerve Bifurcation Shorten Block Onset Time?
Following foot and ankle surgery, ultrasound-guided sciatic nerve block (SNB) at the popliteal fossa decreases post-operative pain and opioid consumption.
- Conditions
- Post Operative Analgesia, Regional Anesthesia, Sciatic Nerve Block
- Trial name
- NCT01568476
- Testing
- Distal, Interneural
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- University Health Network, Toronto
Pain
Interscalene Nerve Blocks With Ropivacaine Alone, With Dexamethasone, Plus Systemic Dexamethasone
This study will test the hypothesis that ropivacaine in combination with either systemic or local steroid provides comparably longer-lasting analgesia tha ropivacaine alone.
- Trial name
- Ropivacaine (NCT00519584)
- Testing
- Ropivacaine, dex, Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 218 people
- Sponsor
- The Cleveland Clinic
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Total Knee Arthroplasty
The Effects of Dexamethasone on the Duration of Sciatic Nerve Blocks
Dexamethasone is a commonly used steroid. This medication has been used for many years by physicians for many different indications.
- Trial name
- NCT00616603
- Testing
- Ropivacaine, Dexamethasone, Normal Saline
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Loma Linda University
Anesthesia, Local
Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effects?
Investigators will assess if perineural dexamethasone can increase the duration of an ulnar nerve block when controlling for systemic effects in healthy volunteers.
- Trial name
- NCT04817982
- Testing
- Perineural dexamethasone, Lidocaine, Systemic dexamethasone
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Pain, Postoperative, Pain, Acute
Dexamethasone Versus Dexmedetomidine as Adjuvants for Nerve Blocks
When used as perineural (PN) adjuvants to local anesthetics (LAs), dexamethasone (DX) and dexmedetomidine (DXD) have been well documented to prolong the duration of peripheral nerve blocks.
- Conditions
- Pain, Postoperative, Pain, Acute, Upper Extremity Injury
- Trial name
- NCT03610893
- Testing
- Dexamethasone, Dexmedetomidine
- Where
- Chile
- Volunteers
- 120 people
- Sponsor
- University of Chile
Postoperative Pain
Effect of Dexamethasone and Epinephrine on the Duration of Sciatic Nerve Blocks With Ropivacaine
The aim of the present study is to test that adding dexamethasone or epinephrine significantly prolongs the duration of sciatic nerve blocks with ropivacaine and that the magnitude of the effect differs among dexamethasone and…
- Trial name
- NCT02104778
- Testing
- Dexamethasone, Epinephrine
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Bimalleolar Fractures of the Ankle., Sciatic Nerve Block.
To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade
Clonidine as an adjuvant to local anaesthetics prolongs the postoperative analgesia. It is predominantly an alpha 2 agonist, but does have some alpha 1 activity. Clonidine alone produces analgesia.
- Conditions
- Bimalleolar Fractures of the Ankle., Sciatic Nerve Block., Saphenous Nerve Block., Post Operative Analgesia Duration.
- Trial name
- NCT01759524
- Testing
- Bupivacaine, Lidocaine
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Rib Fractures
Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Rib fractures are common injuries in accident patients and can be associated with significant pain during recovery. If poorly controlled, pain from splinting due to rib fractures can result in difficulty in breathing leading to…
- Trial name
- NCT02604589
- Testing
- hydromorphone hydrochloride, Infusion catheter placement, bupivicaine 0.25%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Anthony Iacco
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Low Back Pain Due to Spinal Nerve Compression
Determination of a Proper Needle Entry Point; Effects of Skin Compression With an Indicator on Radiation Exposure Time of Fluoroscopically Guided Transforaminal Epidural Block in Obese Patients
To evaluate the effects of skin compression with an indicator at the needle entry point on radiation exposure time of fluoroscopically guided transforaminal epidural block in obese patients
- Trial name
- NCT02281227
- Testing
- skin compression
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Regional Anesthesia Block, Upper Limb Surgery
An Integrated Artificial Intelligence Approach for Predicting Analgesic Time Based on Nalbuphine Versus Morphine as Adjuvants to Bupivacaine in Ultrasound-Guided Supraclavicular Block
This study investigated the effect of adding nalbuphine or morphine to bupivacaine for supraclavicular brachial plexus block in upper limb surgeries.
- Trial name
- NCT07008443
- Testing
- Bupivacaine + saline, Bupivacaine + nalbuphine, Bupivacaine + morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alzahraa Ahmed Abbas
Pain
Dexamethasone With TAP Block Increasing the Duration of the Peripheral Nerve Block in Caesarian Section
Nowadays Cesarean sections became the most popular surgery worldwide with the consumption of the hospital resources and the continuous need to decrease the costs, work load and medical stuff engagement.
- Trial name
- NCT02440880
- Testing
- Dexamethasone in addition to TAP block in dose of 4 mg, Dexamethasone in combination with TAP block in dose of 8 mg, Dexamethasone intravenous 4mg+ TAP block
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Onset and Duration of a Digital Nerve Block
Determination of the Duration of Action of a Lidocaine and a Bupivacaine Digital Nerve Block in Human Volunteers
The duration of the autonomic (sympathetic) block will last longer than the sensory block. The duration of the increased perfusion index will last longer than either the sympathetic or sensory block.
- Trial name
- NCT01508832
- Testing
- Lidocaine Digital Nerve Block, Bupivacaine Digital Block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Neuromuscular Blockade
Improving Neuromuscular Monitoring and Reducing Residual Neuromuscular Blockade Via E-learning
To assess the impact of an e-learning course in neuromuscular monitoring on the frequency of application of objective neuromuscular monitoring for assessment of depth of neuromuscular blockade in general anaesthesia and…
- Trial name
- INVERT (NCT02925143)
- Testing
- E-learning course in neuromuscular monitoring
- Where
- Denmark
- Volunteers
- 6,525 people
- Sponsor
- Herlev Hospital
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina