Clinical trials: Nerve Blocks
Post Operative Pain, Laparoscopic Surgery
Modified Thoracoabdominal Nerve Block(M-TAPA) in Pediatric Laparoscopic Appendectomies
To compare the effect of M-TAPA block and port-site local anesthetic infiltration on postoperative pain in pediatric laparoscopic appendectomies.
- Conditions
- Post Operative Pain, Laparoscopic Surgery, Pediatrics, Regional Anesthesia
- Trial name
- M-TAPA (NCT06039150)
- Testing
- M-TAPA Block, Local anesthetic infltration to port sites
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gulhane Training and Research Hospital
Perioperative Inflammatory Response, Postoperative Pain
Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries
the aim is to determine the value of adding bilateral supra zygomatic maxillary nerve block to general anesthesia in attenuating the systemic inflammatory response in paediatrics.
- Trial name
- NCT05495750
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alaa Mohamed Abdel Salam Ibrahim Soliman
Analgesia
Tourniquet Pain Prevention During Distal Upper Limb Surgery
Post-tourniquet pain remains a common problem. It disturbs the quality of anesthesia during brachial plexus block for distal upper-limb surgery.
- Trial name
- NCT07784426
- Testing
- Selective ultrasound guided Intercostobrachial nerve block, Serratus anterior plane block
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Cholecystitis
Efficacy Of M-TAPA and TAP Block Following Laparoscopic Cholecystectomy
Cholecystectomy is the most common abdominal surgical procedure in developed countries Laparoscopic cholecystectomy is considered the gold standard surgical technique for gallstones.
- Trial name
- NCT06198335
- Testing
- Modified Perichondral Approach Thoracoabdominal Nerve block, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mursel Ekinci
Pain, Postoperative
Blood Ropivacaine Concentrations Following Chest Wall Nerve Block Continuous Infusion
The main objective of this proposed investigation is to evaluate blood ropivacaine concentrations in infants and toddlers following the initiation of, and over the course of, continuous paravertebral nerve blockade using…
- Trial name
- NCT02860091
- Testing
- Ropivacaine infusion
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston Children's Hospital
Healthy Human Volunteers
Continuous Adductor Canal Nerve Blocks: Relative Effects of a Basal Infusion v. Hourly Bolus Doses
Patients usually experience moderate-to-severe pain following the knee replacement that is often treated with a femoral nerve block (injection of numbing medicine placed around the main nerve of the knee joint).
- Trial name
- NCT02219438
- Testing
- Bolus, Basal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Post-Traumatic Headache
Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 2
Anesthetic greater occipital nerve (GON) blockade is a simple, inexpensive, and safe procedure that has demonstrable headache pain suppressing effects.
- Trial name
- NCT07796074
- Testing
- Bupivacaine bilateral greater occipital nerve block
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
Cardiac Surgery
Transversus Thoracis Plane Block Versus Parasternal Intercostal Nerve Plane Block for Cardiac Surgery
Traditionally postoperative pain management after cardiac surgery has been based on opiate analgesics. However, opiates have some undesirable dose-related side-effects such as nausea, constipation, vomiting, dizziness, mental…
- Trial name
- NCT06155097
- Testing
- transversus thoracis muscle plane block (TTP), parasternal intercostal nerve block (PSI block)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Zagazig University
Post Operative Pain Management
Peri-capsular Nerve Group Block Versus Fascia Iliaca Block for Hip Arthroplasty
In this study, the investigator will examine the efficacy of Pericapsular nerve group (PENG) block in hip surgeries as a post-operative pain management technique in comparison with fascia Iliaca block in hip surgeries
- Trial name
- NCT03783247
- Testing
- Pericapsular nerve group block, Fascia Iliaca BLock
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Headache, Pregnancy Related
Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine
This is an open label randomized controlled trial evaluating response to bupivacaine occipital nerve block compared to Tylenol/Caffeine cocktail in treatment of pregnant patients seeking care of headache.
- Conditions
- Headache, Pregnancy Related, Occipital Nerve Block
- Trial name
- NCT03951649
- Testing
- Occipital Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hemiplegia, Stroke
Comparison of the Efficacy of Ultrasound Guided vs Non-guided Suprascapular Nerve Block Treatment in Stroke Patients
The aim of this study is to compare the effectiveness of ultrasound-guided and non-guided suprascapular nerve block in the treatment of patients with hemiplegic shoulder pain, which is one of the most common post-stroke…
- Trial name
- NCT05260125
- Testing
- Ultrasound-guided Suprascapular Nerve Block, Anatomical Landmark-guided Suprascapular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Abant Izzet Baysal University
Regional Anesthesia, Femoral Nerve Block
Comparison of the Sensitive Cutaneous Block Distribution Following Femoral Nerve Block Using Two Femoral Block Techniques
In this study, we will be comparing two approaches to the femoral block. The first or classical approach and one that is the most popular in our institution is used by combining ultrasound guidance and neurostimulator to do the…
- Trial name
- NCT02721290
- Testing
- Femoral nerve block using Ultrasound and neurostimulator, Femoral nerve block using Ultrasound, Ropivacaine 0.5%
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Diabetic Retinopathy, Retinal Vein Occlusion
Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph
Blindness can be caused by many ocular diseases, such as diabetic retinopathy, retinal vein occlusion, age-related macular degeneration, pathologic myopia and glaucoma.
- Conditions
- Diabetic Retinopathy, Retinal Vein Occlusion, Retinal Artery Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT04723160
- Testing
- Software assisted imaging diagnosis
- Where
- 5 sites in China
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Visionary Intelligence Ltd.
Breast Surgery, Erector Spinae Plane Block
A Comparative Study of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block on Postoperative Opioid Consumption Following Breast and Axillary Dissection Surgery
Breast surgery is one of the most common surgical procedures worldwide. Pain after surgery is an important issue because it affects recovery and mobility. It can also increase the risk of breathing problems.
- Conditions
- Breast Surgery, Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- NCT06833697
- Testing
- erector spinae plane block, serratus posterior superior intercostal plane block, 0.25% bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Anterior Cruciate Ligament Rupture, Femoral Nerve Block
FNB in ACL Recon Under SA
The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for anterior cruciate ligament reconstruction under spinal anesthesia.
- Trial name
- NCT06048874
- Testing
- Sono-guided injection, Ropivacaine injection, Saline injection
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Quality of Recovery
Effects of Transcutaneous Electrical Nerve Stimulation for Postoperative Quality of Recovery After Shoulder Surgery
Transcutaneous Electrical Nerve Stimulation (TENS) has been reported to reduce postoperative pain scores and opioid consumption after postoperative.
- Trial name
- NCT05833113
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Pain, Joint Function Disorder
Genicular Nerve Block in Rheuamtoid Arthritis
N=64 RA patients either early or established disease diagnosed after ACR/EULAR criteria 2010 with unilateral persistent knee arthritis.
- Conditions
- Pain, Joint Function Disorder, Inflammation
- Trial name
- NCT04361513
- Testing
- Bupivacaine hydrochloride 0.5% (Marcaine, Pfizer), triamcinolone 40 milligrams (Kenacort, Bristol Myers Squip)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Sohag University
Deviated Nasal Septum
Septorhinoplasty Post-operative Pain Control With SPG Nerve Block
Maxillary nerve blocks have been shown to significantly reduce post-operative pain and analgesic intake during the 24-hour period following sinus surgery.
- Trial name
- NCT05667324
- Testing
- Ropivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Florida
Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion
New Non-invasive Modalities for Assessing Retinal Structure and Function
This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other…
- Conditions
- Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion, Hemianopia, Leber Hereditary Optic Neuropathy
- Trial name
- NCT03475173
- Testing
- LSFG-NAVI
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Pain Perception, Local Anesthesia
Pain Perception Comparison of Computerized vs Conventional Injection Methods
This study was conducted to a Comparison of Pain Perception for Nerve Block and Infiltration Injection Using the Conventional Method and Two Computerized Control Systems.
- Trial name
- NCT06129162
- Testing
- Conventional Syringe, STA Single Tooth Anesthesia® System., Star Pen anesthesia device.
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University