Clinical trials: Nerve Examination
Neuromyelitis Optica
Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD
NMOSDCopilot is a digital tool developed for the self-assessment of Neuromyelitis Optica Spectrum Disorder symptoms that impact patients' functioning and quality of life.
- Trial name
- OPTIS (NCT05566769)
- Testing
- NMOSDCopilot smartphone application
- Where
- 22 sites in United States, France and 1 more
- Volunteers
- 103 people
- Sponsor
- Ad scientiam
Trauma, Brain, Subarachnoid Hemorrhage
Non-invasive ONSD-based Neuromonitoring in a Neurointensive Care Setting
Intensive care patients with established invasive intracranial neuromonitoring due to neurotrauma are subjected to a repeated non-invasive sonographic recording of the optic-nerve-sheath-diameter (ONSD).
- Conditions
- Trauma, Brain, Subarachnoid Hemorrhage, Intracranial Hypertension
- Trial name
- ONSDDynamics (NCT05818371)
- Testing
- Sonographic determination of the optic nerve sheath diameter
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Non-arteritic Ischemic Optic Neuropathy
Assessment of Visual Field-related Endpoints in Patients With Non-arteritic Ischemic Optic Neuropathy
This present research project intends to collect five quantitative test series: perimetric examination using static stimuli, assessing the entire (80 degree) visual field with a fast thresholding algorithm (GATE) [Schiefer 2008]…
- Trial name
- Pilot-SINN (NCT01614158)
- Testing
- perimetry, D-BCVA, RAPD
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital Tuebingen
Corticobasal Syndrome, Progressive Supranuclear Palsy
Diagnosing Frontotemporal Lobar Degeneration
To establish diagnostic tools to make an accurate clinical and pathological diagnosis of patients with clinical FTLD syndromes
- Conditions
- Corticobasal Syndrome, Progressive Supranuclear Palsy, Behavioral Variant Frontotemporal Dementia, Semantic Dementia
- Trial name
- NCT02964637
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
PSP - Progressive Supranuclear Palsy, PD - Parkinson's Disease
Chromatic Pupillometry to Assess the Melanopsin-Light Pathway in Progressive Supranuclear Palsy
The specific aim of this study is to investigate rod, cone and melanopsin driven pupillary light response in individuals with progressive supranuclear palsy (PSP), age-matched healthy controls and individuals with other…
- Conditions
- PSP - Progressive Supranuclear Palsy, PD - Parkinson's Disease, AD - Alzheimer's Disease, ALS (Amyotrophic Lateral Sclerosis)
- Trial name
- PMPSP (NCT03330353)
- Testing
- Pupillometry
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Dyspepsia
High Resolution Gastric Mapping and Gastroduodenal Manometry
Dyspepsia is a common problem attributed to gastric sensorimotor dysfunctions ie, delayed, or less frequently rapid gastric emptying (GE), impaired gastric accommodation, and increased gastric sensation.
- Trial name
- NCT06941545
- Testing
- Alimetry, tVNS, Gastroduodenal Manometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Strabismus
Virtual Reality Test of Strabismus
Strabismus, or squint, describes any misalignment of the eyes, and can affect both children and adults. As a result, the images of the outside world conveyed to the brain from the two eyes do not correspond, which can result in…
- Trial name
- NCT04156763
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Julie Dawson
Meniere's Disease, Benign Paroxysmal Positional Vertigo
CAVA: Dizziness Trial
Clinical investigation of a medical device (CAVA) for recording eye movements. Patients suffering from diagnosed dizziness conditions will wear the device for 23 hours a day, for 30 days.
- Conditions
- Meniere's Disease, Benign Paroxysmal Positional Vertigo, Recurrent Vestibulopathy, Vestibular Migraine
- Trial name
- CAVA (NCT04026516)
- Testing
- CAVA Device
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Glioblastoma
Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma
The main goal of this study is to provide foundational data to drive translational approaches for an entirely novel category of immunotherapy.
- Trial name
- LAMB-G (NCT04657146)
- Testing
- Biorepository
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Nerve Disorders
The Use of i/t Curve in Assessment of Phototherapy Effects
Conventional electrodiagnostic examination is useful in daily physiotherapeutic practice. Nevertheless, the subjective assessment of muscle contraction and perceived current vibrations carries the risk of error and thus is a…
- Trial name
- NCT02618642
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Trigeminal Neuralgia
Resting-State fMRI Study of Functional Connectivity After Gamma Knife Radiosurgery in Trigeminal Neuralgia
Trigeminal neuralgia is a severe chronic pain condition with a major impact on quality of life. Although Gamma Knife radiosurgery is an established treatment for pharmacoresistant trigeminal neuralgia, its mechanisms of action…
- Trial name
- DOCTRINE (NCT07357025)
- Testing
- Resting-State Functional MRI
- Volunteers
- 28 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Carpal Tunnel Syndrome (CTS)
Graded Motor Imagery in Carpal Tunnel Syndrome
The aim of this study is to investigate whether the addition of Graded Motor Imagery (GMI) to progressive neurodynamic exercises is more effective than progressive neurodynamic exercises alone in individuals with carpal tunnel…
- Trial name
- NCT07800260
- Testing
- Graded Motor Imagery (GMI), Progressive Neurodynamic Exercise, Nighttime Resting Splint
- Volunteers
- 46 people
- Sponsor
- Artvin Coruh University
Cubital Tunnel Syndrome
Comparative Efficacy of Soft Tissue Mobilization and Ulnar Nerve-Specific Strengthening Exercises in Patients With Cubital Tunnel Syndrome
Cubital tunnel syndrome occurs when the ulnar nerve is compressed or irritated near the elbow. It can cause elbow or forearm pain, numbness or tingling in the ring and little fingers, hand weakness, and difficulty performing…
- Trial name
- NCT07797023
- Testing
- Soft Tissue Mobilization, Ulnar Nerve-Specific Strengthening and Nerve-Gliding Exercises
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Hamna Sarfraz
Autism Spectrum Disorder
Study of Application of Transcutaneous Trigeminal Nerve Stimulation on Autism Spectrum Disorder
This study aims to evaluate the safety and the efficacy of applying transcutaneous trigeminal nerve stimulator (NuEyne P01) on autism spectrum disorder.
- Trial name
- NCT06233279
- Testing
- Charge-Balanced, Symmetric Nerve Stimulation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Nu Eyne Co., Ltd.
Carpal Tunnel Syndrome, Physical Therapy Modalities
Pulsed US Versus SWD in Carpal Tunnel Syndrome
The goal of this clinical trial is to compare two physical therapy treatments in people with mild-to-moderate carpal tunnel syndrome (CTS). CTS is a condition that causes pain, numbness, and weakness in the hand.
- Conditions
- Carpal Tunnel Syndrome, Physical Therapy Modalities, Ultrasound Therapy
- Trial name
- NCT07545161
- Testing
- Pulsed Therapeutic Ultrasound, Pulsed Shortwave Diathermy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Tennis Elbow, Physical Therapy Modalities
Effectiveness of Radial Nerve Mobilization for Chronic Epicondylalgia
Effectiveness of radial nerve mobilization techniques and their interfaces for treating chronic epicondylalgia Intervention: This is a randomized controlled clinical trial that will evaluate the effectiveness of adding radial…
- Trial name
- NCT07146620
- Testing
- Forearm massage, Pressure release for forearm trigger points, Mulligan mobilization with movement technique
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universitat Internacional de Catalunya
Brain Metastases, Glioma of Brain
Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases
Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) is a potentially powerful diagnostic tool for the management of brain cancer and other conditions in which the blood-brain barrier is compromised.
- Conditions
- Brain Metastases, Glioma of Brain, Brain Tumor, Metastatic Melanoma
- Trial name
- NCT03698162
- Testing
- Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Bevacizumab Injection
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Southern California
Pain, Osteoarthritis
Adductor Canal Block With Posterior Capsular Injection for Total Knee Replacement
To compare early ambulation and ability to participate in rehabilitation in patients undergoing total knee replacement using two different nerve block techniques for pain control.
- Trial name
- NCT01805661
- Testing
- Canal Block and Capsular Injection, Femoral with Tibial Nerve Block
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Trinity Health Of New England
Craniopharyngioma
Examination of Sleep and Family Functioning in Pediatric Craniopharyngioma Patients
Pediatric craniopharyngioma patients experience significant endocrine and sleep dysregulation difficulties. Sleep is a crucial part of children's healthy development, and sleep difficulties are associated with severe functional…
- Trial name
- NCT03330080
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- St. Jude Children's Research Hospital
Rheumatoid Arthritis
Nerve Conduction Study for Assessment of Peripheral Neuropathy in Rheumatoid Arthritis Patients on the Janus Kinase Inhibitor Baricitinib
Rheumatoid arthritis is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues.
- Trial name
- NCT06977035
- Testing
- Nerve Conduction Study
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University