Clinical trials: Nervous System
Meningioma
Embolization for Meningioma
The natural course for meningioma suggests that a majority will grow over time. Treatment is usually indicated in growing or symptomatic meningiomas.
- Trial name
- e-men (NCT05416567)
- Testing
- Endovascular embolization
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Carpal Tunnel Syndrome
Vitamin B12 and Dextrose for Median Nerve Hydrodissection
Carpal tunnel syndrome is the most common peripheral entrapment neuropathy of the upper limb. Previous experiments found that ultrasound-guided median nerve hydrodissection with 5% dextrose water could ameliorate the condition of…
- Trial name
- NCT05423028
- Testing
- Ultrasound-guided nerve hydrodissection
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng-Kung University Hospital
Pain
Assessment of Peripheral GABA Receptors for Local Pain Relief
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human subjects has never been investigated.
- Trial name
- NCT02928328
- Testing
- GABA oral solution, Intramuscular GABA, Pain modulation
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Chronic Fatigue Syndrome
Valganciclovir (Valcyte) for Chronic Fatigue Syndrome Patients Who Have Elevated Antibody Titers Against Human Herpes Virus 6 (HHV-6)and Epstein-Barr Virus (EBV)
The purpose of this study determine whether the drug valganciclovir has a significant and real benefit on the central core of symptoms experienced by patients who have high titers to EBV and HHV-6 and are experiencing…
- Trial name
- NCT00478465
- Testing
- valganciclovir
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Postoperative Pain, Inferior Alveolar Nerve Block Failure
Evaluation of Systemic Inflammatory Index and Biomarkers in Relation to Inferior Alveolar Nerve Block Success and Postoperative Pain
This study aims to investigate the relationship between systemic inflammatory markers and the effectiveness of inferior alveolar nerve block anesthesia in patients undergoing dental treatment.
- Conditions
- Postoperative Pain, Inferior Alveolar Nerve Block Failure, Inflammation Biomarkers, Dental Anesthesia Complications
- Trial name
- NCT07163065
- Testing
- Inferior Alveolar Nerve Block Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- KEZBAN MELTEM ÇOLAK
Critical Illness, Muscle Weakness
Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients?
The rapid decline of muscle mass and function in mechanically ventilated critically ill patients is associated with prolonged length of mechanical ventilation, prolonged intensive care (ICU) and hospital stay, increased ICU and…
- Trial name
- HMB-ICU-CH (NCT03628365)
- Testing
- HMB (beta-hydroxy beta-methylbutyrate)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Mette M Berger
Fibromyalgia, Sleep
Change on Sleep Quality of Patients With Fibromyalgia Subjected to a Protocol Based on Physical Exercise and Stretching
This study evaluates the effect to a muscle stretching program combined with physical exercise versus a physical exercise program in patients with fibromyalgia.
- Conditions
- Fibromyalgia, Sleep, Stretch
- Trial name
- NCT02876965
- Testing
- Muscle Stretching, Physical Exercise
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Cardenal Herrera University
Hemangioma, Cavernous, Central Nervous System
Study on Treatment Decision-Making and Prognostic Follow-Up for Untreated Cerebral Cavernous Malformations
The goal of this observational study is to evaluate and predict the risk associated with cerebral cavernous malformations (CCMs) using advanced artificial intelligence and radiomics analysis technology.
- Trial name
- NCT06214767
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Beijing Tiantan Hospital
Musculoskeletal Discomfort, Ergonomic Risk Perception
Musculoskeletal Discomfort and Ergonomic Factors in Midwifery Students
The aim of this observational study is to assess regional musculoskeletal discomfort, ergonomic risk perception, and protective ergonomic behaviors among undergraduate midwifery students at Mardin Artuklu University, Türkiye.
- Conditions
- Musculoskeletal Discomfort, Ergonomic Risk Perception, Protective Ergonomic Behaviours, Clinical Task Exposure
- Trial name
- NCT07873567
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Chronic Pain
VETERANS AFFAIRS AUGUSTA
Chronic pain is a prevalent and debilitating condition among Veterans, often accompanied by depression, anxiety, sleep disturbances, and social isolation.
- Trial name
- NCT07776600
- Testing
- My AI Companion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Companion IQ, Inc
Cortical/Cerebral Visual Impairment, Cerebral Palsy
Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment
The goal of this study is to learn about eye gaze technology's use as an assessment and intervention of visual skills and the impact on occupational performance in children with cortical/cerebral visual impairment.
- Trial name
- NCT06067607
- Testing
- eye gaze technology
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rockhurst University
Depression - Major Depressive Disorder, Catatonia
Optimizing Stimulation Parameters for Electroconvulsive Therapy
The goal of this clinical trial is to improve how electroconvulsive therapy (ECT) stimulation settings are chosen. Researchers will use real-time brain monitoring to measure both seizures and a recently identified brain event…
- Trial name
- PRESTO (NCT07561307)
- Testing
- Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pennsylvania
Radiculopathy, Low Back Pain
Low Back Study to Compare Traditional Physical Therapy With Combined Therapy Protocol
The most common chronic low back pain conditions are a consequence of disc disease as well as muscular and bony etiologies. The discs degenerate and weaken, bulge and are pushed into the space containing the spinal cord or a…
- Trial name
- NCT01236092
- Testing
- conservative therapy - traction, vibration, exercise
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Michael Wilson & Associates Health Care Consulting, LLC
Stroke
MTPr With Shockwave on Pain & Function of SHS in Stroke
Background: shoulder-hand syndrome is considered a significant reason for the reduction of upper limb functions after stroke. Purpose: To investigate the influence of Myofascial Trigger Points (MTrPs) release and shockwave…
- Trial name
- NCT04627636
- Testing
- Myofascial trigger points pressure (MTrP) release, Shockwave therapy application, conventional therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Gingival Recession, Mucogingival Surgery
Effects of Low-Level Laser Therapy and Hyaluronic Acid After Free Gingival Graft
The goal of this randomized clinical trial was to learn whether low-level laser therapy or hyaluronic acid application improves healing after free gingival graft surgery in adults with insufficient keratinized gingival tissue in…
- Trial name
- NCT07751211
- Testing
- Topical Hyaluronic Acid Gel, Low-Level Laser Therapy, Free Gingival Graft Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Altinbas University
Stroke, Hemiplegia
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
- Conditions
- Stroke, Hemiplegia, Chronic Stroke
- Trial name
- NCT07725211
- Testing
- Neurodevelopmental Treatment, High-Repetition Task-Oriented Training, High-Intensity Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University - Cerrahpasa
Sarcopenia
Functional Exercise for Sarcopenia
Sarcopenia is one of the major causes of functional decline and negative health outcomes among older adults. Prominent evidence suggests exercise interventions can reverse sarcopenia.
- Trial name
- STEP (NCT05570136)
- Testing
- Functional Exercise, Education
- Where
- 7 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Alzheimer Disease
Pilot Clinical Study of CT1812 in Mild to Moderate Alzheimer's Disease Using EEG
This is a single-site, randomized, double-blind, placebo-controlled, 29-day, 2-period crossover Phase 2 study of 1 dose level of CT1812 (active) or placebo in adults with mild to moderate AD.
- Trial name
- NCT04735536
- Testing
- CT1812
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Cognition Therapeutics
Traumatic Brain Injury
A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury
The study is intended to cover two purposes: first, to develop a blood-based biomarker test for aiding the diagnosis of traumatic brain injury (TBI) in adult participants and for prognosis of outcome of TBI (CLIN12.1); and…
- Trial name
- NCT07455136
- Testing
- Blood sample collection
- Where
- 14 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Hoffmann-La Roche
Taste Disturbance
Taste Disorders in Middle Ear Disease and After Middle Ear Surgery
Objectives To evaluate the impact of taste disturbance in different types of chronic middle ear diseases and after middle ear surgery.
- Trial name
- NCT01584011
- Testing
- taste measurement, Symptom questionnaire, Quality of life questionnaire
- Where
- Sweden
- Volunteers
- 310 people
- Sponsor
- Uppsala University