Clinical trials: Nervous System Complication
Diabetic Neuropathy, Proprioception
Additional Effects of Sensory Integration Along With Focused Regimen Exercises on Kinaesthesia & Proprioception in Diabetic Peripheral Neuropathy.
This study aims to evaluate Additional Effects of sensory integration along with focused regimen exercises on kinaesthesia \& proprioception in Diabetic peripheral neuropathy Peripheral neuropathy a Condition occur when the…
- Trial name
- NCT07332364
- Testing
- Sensory integration and focused regimen, Focused Regimen Exercise
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Pregnancy Related, Pregnancy Disease
Fetal Autonomic Nervous sysTem Evaluation
The autonomic nervous system (ANS) is involved in cardiovascular, metabolic and cognitive processes, so its study in the fetus can provide relevant functional diagnostic and prognostic information.
- Conditions
- Pregnancy Related, Pregnancy Disease, Pregnancy Complications, Pre-Eclampsia
- Trial name
- FANTE (NCT06330987)
- Testing
- electrocardiograph
- Where
- Italy
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Breast Neoplasms, Analgesia
Analgesic Efficacy of U/S Retrolaminar Block and Erector Spinae Plane Block in MRM
Modified radical mastectomy (MRM) is the most commonly performed surgical procedure in breast cancer patients and is usually associated with severe postoperative pain.
- Trial name
- NCT06322316
- Testing
- The Ultrasound-guided Retrolaminar Block Group, The Ultrasound-guided Erector Spinae Plane Block Group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Atherosclerosis, Coronary Artery Disease
Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution
The main goal of this clinical trial is to evaluate the feasibility of conducting a large-scale clinical trial testing a program containing several aspects for reducing the effects of air pollution on cardiovascular health (which…
- Conditions
- Atherosclerosis, Coronary Artery Disease, Peripheral Arterial Disease, Ischemic Stroke
- Trial name
- NCT06261606
- Testing
- Hybrid strategy
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Parham Sadeghipour
Diabetic Neuropathy
Efficacy of γ-linolenic Acid and Thioctic Acid in Patients With Diabetic Neuropathy
This study was a 12-week, multi-center, randomized, double-blind, double dummy, parallel clinical trial to compare the efficacy of γ-linolenic acid and Thioctic acid in patients with diabetic neuropathy.
- Trial name
- NCT03914404
- Where
- 11 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Chonbuk National University Hospital
Diabetic Neuropathies, Plantar Callus
Short-term Effect of Podiatric Callus Debridement on Plantar Pressure in Diabetic Neuropathic Patients
Diabetes peripheral neuropathy (DPN) affects up to 50% of the diabetes population. In the diabetic neuropathic foot, it commonly manifests as loss of protective sensation, foot deformity and skin dryness.
- Trial name
- NCT06357884
- Testing
- Callus debridement
- Where
- Hong Kong
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Obstructive Sleep Apnea, Pregnancy Induced Hypertension
Sleep Quality in Pregnancy and Its Impact on Pregnancy Outcomes
Hypothesis:Sleep Disorders are very common during pregnancy but the their exact role in causation of pregnancy related disorders is yet to be determined.
- Conditions
- Obstructive Sleep Apnea, Pregnancy Induced Hypertension, High-Risk Pregnancy, Restless Leg Syndrome
- Trial name
- NCT02016638
- Testing
- Polysomnography and ambulatory blood pressure recording
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Osteoarthritis,Knee
Efficacy of Multimodal Perioperative Analgesia With Periarticular Drug Injection in Total Knee Arthroplasty(TKA)
The purpose of this study is to compare different medication combinations used in a periarticular injection after total knee replacement surgery(TKR).
- Trial name
- NCT01042093
- Testing
- Ropivacaine, Toradol, Clonidine
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Towson Orthopaedic Associates
Pain Management, Analgesia
Comparison of a Comfort Scale and a Numerical Pain Scale on Opioid Consumption After Surgery
The objective is to show that the use of therapeutic communication tools, in this case a comfort scale, a low cost and simple to implement method, can reduce pain and therefore the consumption of opioids in the postoperative care…
- Trial name
- COMFORT (NCT05234216)
- Testing
- Informed consent, Surgery, Comfort scale
- Where
- 29 sites in France, Lebanon
- Volunteers
- 885 people
- Sponsor
- Rennes University Hospital
Effect of Drug
Analgesia From Conscious Sedation Versus Paracervical Block for Manual Vacuum Aspiration
Miscarriage is one of the major causes of early pregnancy losses. Incomplete miscarriage is a major cause of maternal morbidity and mortality.
- Trial name
- NCT06539143
- Testing
- Lidocaine
- Where
- Nigeria
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Emergence Delirium, Anesthesia
Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children
This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will…
- Trial name
- NCT07799311
- Testing
- propofol 1mg/kg, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Analgesia, Postoperative Pain
Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies
The quadratus lumborum has since 2016 become standard of care for abdominal and retroperitoneal surgeries at UPMC-Shadyside Hospital, replacing paravertebral blocks, and as part of a broader multimodal analgesia institutional…
- Conditions
- Analgesia, Postoperative Pain, Block
- Trial name
- NCT04077398
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Sponsor
- Bruce Ben-David
Sensation Disorders
Relationship Between Sensory Processing and Motor Development
The aim of this study is to analyse correlation between the sensory processing and motor development in preterm infants.
- Trial name
- NCT02889887
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Diabetic Neuropathies
Effect of Foot Muscle Energy Technique in Patients With Diabetic Neuropathy
Foot muscle energy technique and conventional physical therapy program administered in patients with type 2 Diabetic Neuropathy.
- Trial name
- NCT05790421
- Testing
- Foot Muscle Energy Technique, Conventional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- October 6 University
Transcutaneous Vagal Nerve Stimulation (tVNS), Diabetic Polyneuropathy
Effect of Vagus Nerve Stimulation on Pain Intensity, Nerve Conduction Studies and Functional Outcomes in Diabetic Peripheral Neuropathy Patients
To evaluate the efficacy of vagus nerve stimulation in reducing neuropathic pain, symptom severity, electrophysiological studies and functional outcomes in patients with diabetic peripheral neuropathy.
- Trial name
- NCT07405021
- Testing
- Conventional physical therapy program, Transcutaneous auricular vagus nerve stimulation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Postoperative Delirium
Predictors for Postoperative Delirium After Major Noncardiac Surgery in Adults
This research project is an observational cohort study by retrospective chart review of patients that underwent major noncardiac surgery at University Hospital Basel, Switzerland, in the years 2011-2015.
- Trial name
- PODMAS (NCT04460716)
- Testing
- Major noncardiac surgery
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Uveitis, Diabetic Retinopathy
Biomarkers of Common Eye Diseases
To identify biomarkers of common eye diseases based on single-cell sequencing technologies using PBMC samples. These diseases include uveitis, diabetic retinopathy, age-related macular degeneration and polypoid choroidal…
- Conditions
- Uveitis, Diabetic Retinopathy, Age-related Macular Degeneration, Polypoidal Choroidal Vasculopathy
- Trial name
- NCT04101604
- Testing
- Collection of blood samples
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Obstructive Sleep Apnea, Overhydration
Effect of Intermittent Hemodialysis on Sleep Apnea Syndrome in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of decreasing fluid overload by hemodialysis on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease on intermittent hemodialysis.
- Conditions
- Obstructive Sleep Apnea, Overhydration, End Stage Renal Disease
- Trial name
- SASinHD (NCT01860209)
- Testing
- Hemodialysis
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Pain, Trismus
Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery
The aim of this study was to evaluate the effectiveness of concentrated growth factor (CGF) on soft tissue healing and postoperative side effects following third molar surgery.
- Conditions
- Postoperative Pain, Trismus, Edema
- Trial name
- CGF (NCT03913884)
- Testing
- Concentrated growth factor, Non-Concentrated growth factor Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
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