Clinical trials: Nervous System Complication
Amputation, Traumatic
Relationship Between Gait Variability and Sensation
Twenty individuals who were referred to receive physiotherapy will be participants of the study. Participants with lower limb loss will evaluate with the following assessment tools: Demographic datas; age, gender, height, body…
- Trial name
- NCT02934074
- Testing
- No intervention
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Neuromuscular Diseases
Oscillation and Lung Expansion (OLE) Therapy for Treatment of Neuromuscular Disease (NMD) Patients
The study will be a non-randomized open label pilot study comparing a retrospective control period to an active treatment period with oscillation and lung expansion (OLE) therapy.
- Trial name
- NCT05366010
- Testing
- Oscillation and Lung Expansion (OLE) therapy
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Baxter Healthcare Corporation
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Microvascular Disease, Microvascular Complications
Comparison of Differencens in VO2-max, Perfusion of the Heart and Brain and Cognitive Performance Between Patients with Type 2 Diabetes and Healthy Age Matched Controls.
In the aging population, ischemic heart disease, stroke and dementia are increasingly prevalent. Diagnosis and treatment of the former two i.e., large-vessel coronary heart disease and endovascular thrombectomy of the brain in…
- Conditions
- Microvascular Disease, Microvascular Complications, Dementia, Diabetes Mellitus Type 2
- Trial name
- SVAT (NCT06628297)
- Testing
- PET
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Postoperative Delirium (POD)
Intranasal Insulin for Postoperative Delirium in Older Patients With T2DM
Postoperative delirium (POD) is highly prevalent in older patients with type 2 diabetes mellitus (T2DM). Cerebral insulin resistance is considered a key pathophysiological mechanism underlying this association.
- Trial name
- NCT07720479
- Testing
- Insulin, human
- Volunteers
- 210 people
- Sponsor
- Weidong Mi
Diabetic Retinopathy, Low Vision
Diabetic Retinopathy Tethered Augmented Reality With Eye4 Study
Diabetes has reached epidemic levels in North America and with it, diabetic retinopathy is increasingly affecting the vision of millions of people.
- Trial name
- DRTARES (NCT05491746)
- Testing
- Eye4
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Eyedaptic
Arthritis Knee, Knee Osteoarthritis
The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty
Pain control and early range of motion following total knee arthroplasty are essential for patient satisfaction. Intraoperative steroids (dexamethasone) have been shown to have a significant effect in controlling acute pain…
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Trial name
- NCT06489626
- Testing
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Where
- 2 sites in United States
- Sponsor
- F. Johannes Plate
Magnesium, Emergence Delirium
Oral Versus Intravenous Magnesium on Emergence Delirium
This prospective randomized controlled study will be conducted to compare the effects of preoperative oral magnesium and intraoperative IV magnesium on the incidence and severity of emergence delirium in children undergoing…
- Conditions
- Magnesium, Emergence Delirium, Children, Adenotonsillectomy
- Trial name
- NCT07655817
- Testing
- Magnesium glycinate, Magnesium sulfate injection, Oral juice and intravenous saline
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Tanta University
Stroke
Stroke complicAtions After TraUmatic expeRieNces and Stress
The primary aim of this retrospective cohort study is to test the hypothesis that previous traumatization (long) before an ischemic stroke increases the degree of stroke-induced PTSD symptoms at 9-13 months after the stroke…
- Trial name
- SATURN (NCT03496480)
- Testing
- Questionnaires
- Where
- Germany
- Volunteers
- 636 people
- Sponsor
- Johanna Schöner
Obstructive Sleep Apnea
Mucosal Inflammation in Children With OSA
Objectives: Variability of clinical phenotypes in childhood obstructive sleep apnoea (OSA) has prompted research for biomarkers to identify patients at risk of developing OSA-related complications.
- Trial name
- NCT06452979
- Where
- Hong Kong
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Polyneuropathy, Diabetic
Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt
The purpose of the study is to find out whether ALA is effective and safe for treating Egyptian diabetic patients with symptomatic polyneuropathy.
- Trial name
- MIRACLE-ALA (NCT05813496)
- Testing
- Alpha-Lipoic Acid (ALA)
- Where
- 5 sites in Egypt
- Volunteers
- 430 people
- Sponsor
- Eva Pharma
Knee Arthroplasty, Total, Peripheral Nerve Block
Postoperative Analgesia in Bilateral Knee Arthroplasties
To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period.
- Conditions
- Knee Arthroplasty, Total, Peripheral Nerve Block, Pain, Postoperative
- Trial name
- NCT06357013
- Testing
- Bilateral Suprainguinal fascia iliaca compartment block, Local infiltration analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Cardiovascular Surgical Procedures, Pain, Postoperative
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB…
- Conditions
- Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases
- Trial name
- NCT07557108
- Testing
- Ultrasound-Guided Pectointercostal Fascial Plane Block, Ultrasound-Guided Rectus Sheath Block, Ultrasound-Guided Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Ordu University
Neurogenic Bladder, Diseases of the Lower Urinary Tract: General Conditions
Lower Urinary Tract Dysfunction Database
Patients with neurological disease/injury often suffer from lower urinary tract symptoms, which frequently have a negative impact on the patients' health related quality of life.
- Trial name
- NCT01293110
- Where
- Switzerland
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Muscle Weakness, Mechanical Ventilation Complication
Cycling Exercise in Mechanical Ventilation
Prolonged critical illness renders survivors with increased long-term morbidity associated with high healthcare costs. Muscle weakness and fatigue are reported as the main contributors to long-term poor functional outcomes.
- Trial name
- NCT03581760
- Testing
- Cycling Exercise, Conventional Physiotherapy
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- University Hospital Ostrava
Cesarean Birth, Post Operative Analgesia
The Effect of Lactoferrin on Pain Management Following Cesarean Section
This study evaluates whether lactoferrin, a naturally occurring protein with anti-inflammatory and antioxidant properties, can improve pain control after cesarean section.
- Trial name
- NCT07502235
- Testing
- Lactoferrin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Breast Neoplasms, Pain, Postoperative
Persistent Pain After Breast Cancer Treatment With Docetaxel
Breast cancer treatment is for many patients followed by sequelae, such as persistent pain, sensory disturbances, lymphedema and reduced physical function.
- Conditions
- Breast Neoplasms, Pain, Postoperative, Neuralgia, Lymphedema
- Trial name
- NCT01279018
- Volunteers
- 2,490 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor
Melphalan in Patients With Neoplastic Meningitis
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of melphalan in patients with persistent or recurrent…
- Conditions
- Brain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor, Leukemia, Lymphoma
- Trial name
- NCT00002750
- Testing
- melphalan
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Duke University
Postoperative Delirium
Accompanying Scientific Program for the Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (WB-QC-POD)
In the course of a scientific accompanying program, the project pursues the goal of gaining further insight into a possible connection between various influencing factors and the development of postoperative delirium.
- Trial name
- NCT05847010
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Surgery, Stress
The Effects of Healing Touch on Post Operative Pediatric Patients
The goal of this study is to assess the benefits of Healing Touch, an energy based therapy on post-operative discomfort and the rate of recovery in children.
- Conditions
- Surgery, Stress, Pain, Children
- Trial name
- NCT01738308
- Testing
- Healing Touch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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