Clinical trials: Nervous Vagus
Major Depressive Disorder
tVNS Effects on Motivation in Depression
Attaining goals or rewards commonly entails response costs. In light of cost and benefits, how do participants decide what effort should be put in to give it a shot? Figuratively, you may "go with your gut", but the literal…
- Trial name
- NCT05120336
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Germany
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Parkinsonism
Ultrasound Changes of the Vagus Nerve in Patients With Parkinsonism
In this study, the investigators will assess the Vagus nerve in two groups: Group 1 which include patients with parkinsonism and group 2 which included age and sex matched healthy control.
- Trial name
- NCT05834634
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vagus Nerve Stimulation
Vagus Nerve Stimulation Effects on Autonomic Nervous System Activity
Transcutaneous Auricular Vagus nerve stimulation may be successful in cardiac modulation because of the cardiac connections of the vagal nerve.
- Trial name
- NCT06086236
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Disorders of Consciousness
Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Disorders of Consciousness
Consciousness disorders following severe brain injury refer to a series of disturbances in arousal and cognition secondary to organic brain diseases, including Unresponsive Wakefulness Syndrome (UWS) (also termed Vegetative…
- Trial name
- taVNS (NCT07284732)
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhujiang Hospital
Diabetic Neuropathy With Neurologic Complication
Observational Study of the the Use of a Trigeminal Vagal Nerve Stimulator in the Routine Care of Native Americans With Diabetic Neuropathy Pain. Pain Scores, Drug Use and Glucose Measurements Will be Assessed
This is an observational study that will follow patients in the course of routine care and measure pain levels, glucose assessments and drug utilization for native American patients with diabetic neuropathy
- Trial name
- NCT07025356
- Testing
- Implantation of a trigeminal Vagus cervical nerve stimulator system, Implantation of a neurostimulator system for trigeminal vagal cervical nerve stimulation
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Vagus Nerve Society
Coronary Artery Bypass Grafting (CABG) Surgery, Vagus Nerve Stimulations
Vagus Nerve Stimulation for Autonomic Modulation After Coronary Artery Bypass Graft Surgery
The objective of this randomized clinical trial is to investigate whether transcutaneous auricular vagus nerve stimulation (taVNS) can improve the recovery of patients undergoing coronary artery bypass grafting (CABG) through…
- Trial name
- ENV (NCT07853222)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- 2 sites in Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Recurrent Laryngeal Nerve Injuries
Recurrent Laryngeal Nerve's Motor Function: Sometimes Motor Fibers May Also Be Located in The Posterior Branch
The investigators hypothesized that, sometimes the posterior branch of the recurrent laryngeal nerve may also have motor function.
- Trial name
- NCT02493881
- Testing
- intraoperative neuromonitoring
- Volunteers
- 337 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Ischemic Stroke, Motor Deficits
Effect of Vagus Nerve Stimulation Via the Outer Ear on Motor and Cognitive Deficits After Ischemic Stroke
The goal of this clinical trial is to learn if transcutaneous auricular vagus nerve stimulation (taVNS) works to treat motor and neurocognitive deficits after ischemic stroke when applied within 30 days after onset of stroke.
- Conditions
- Ischemic Stroke, Motor Deficits, Cognitive Impairment, Vagus Nerve Stimulation
- Trial name
- EVAMOS (NCT06822140)
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- Switzerland
- Volunteers
- 144 people
- Sponsor
- Rheinburg-Klinik
TBI Traumatic Brain Injury
Noninvasive Brain Stimulation to Enhance Cognition at Home Following a TBI.
The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous vagus nerve stimulation (tVNS) at home, to enhance cognitive recovery in patients with mild-moderate traumatic brain injury…
- Trial name
- NCT07428980
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Shirley Ryan AbilityLab
Head and Neck Neoplasms, Xerostomia
Foot Reflexology and Ta-VNS for Symptom Management in Head and Neck Cancer During CCRT
Head and neck cancer (HNC) patients undergoing concurrent chemoradiotherapy (CCRT) frequently experience pain, xerostomia, fatigue, sleep disturbance, and other treatment-related toxicities that impair quality of life and…
- Conditions
- Head and Neck Neoplasms, Xerostomia, Cancer-related Fatigue, Pain
- Trial name
- NCT07711626
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
PARKINSON DISEASE (Disorder)
taVNS on Functional Mobility in People With DP
Parkinson's disease (PD) is characterized by motor impairments such as bradykinesia accompanied by resting tremor and/or rigidity.
- Trial name
- NCT07366411
- Testing
- Active taVNS
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Epilepsies, Partial, Epilepsy, Tonic-Clonic
Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study
Evaluate the initial safety and effectiveness of Microburst VNS stimulation in subjects with refractory epilepsy.
- Trial name
- Microburst (NCT03446664)
- Testing
- Microburst Stimulation
- Where
- 9 sites in United States, Belgium
- Volunteers
- 33 people
- Sponsor
- LivaNova
Hyposmia
Treatment of Olfactory Dysfunction Using Vagus Nerve Stimulation
Hyposmia, a reduced sense of smell, is commonly linked to viral infections like COVID-19. Currently, the sole recommended treatment is olfactory training, a method that is both time-intensive and limited in its effectiveness.
- Trial name
- NCT06817499
- Testing
- Nasal Insert + VNS, Nasal Insert
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Dysphagia Following Cerebrovascular Accident
Transcutaneous Auricular Vagus Nerve Stimulation for Treating Post-stroke Dysphagia
The aim of the present project is to use transcutaneous auricular vagus nerve stimulation (t-VNS) for the treatment of dysphagia in acute stroke patients to improve swallowing function and reduce mortality and disability related…
- Trial name
- LOGIC (NCT06827301)
- Testing
- Non Invasive vagus nerve stimulation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Campus Bio-Medico University
Fibromyalgia
taVNS Treatment for Fibromyalgia
In this research study we want to learn more about if transcutaneous electrical nerve stimulation (TENS), a safe electrical stimulation tool, can relieve Fibromyalgia pain.
- Trial name
- NCT04777500
- Testing
- Auricular transcutaneous electrical nerve stimulation device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Vasoconstriction Disorder of Extremities
Response of the Autonomic Nervous System to Auricular Stimulation of the Vagus Nerve (x)
While invasive vagal stimulation has proven its therapeutic effectiveness over the past 20 years, particularly in the treatment of epilepsy or depression, its implementation is hampered by the high cost, high technicality and…
- Trial name
- AURIX (NCT04130893)
- Testing
- stimulation of G13 then G15, stimulation of G15 then G13
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hôpital Européen Marseille
Emergence Agitation, Emergence Delirium
Transcutaneous Auricular Vagus Nerve Stimulation for Prevention of Emergence Agitation and Delirium in Children Undergoing Tonsillectomy and Adenoidectomy
Brief Summary This study is designed to find out whether transcutaneous auricular vagus nerve stimulation (taVNS) can safely reduce restlessness and confusion when children wake up from anesthesia after tonsillectomy and…
- Trial name
- NCT07394647
- Testing
- Active taVNS Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Transcutaneous Vagal Nerve Stimulation (tVNS), Prader-Willi Syndrome
Proof of Concept Study of Vagus Nerve Stimulation
The investigator's recent pilot study of vagus nerve stimulation (VNS) from a surgically implanted medical device to control the excess eating behaviour characteristic of Prader-Willi Syndrome (PWS) found that it was safe and…
- Trial name
- NCT03689621
- Testing
- Transcutaneous vagus nerve stimulation (tVNS)
- Volunteers
- 9 people
- Sponsor
- Jessica Beresford-Webb
Fibromyalgia Syndrome
Effects of Left and Bilateral Transcutaneous Auricular Vagus Nerve Stimulation on Pain, Mood, and Autonomic Function in Female Fibromyalgia Patients
This study aimed to examine the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on pain, depression, anxiety, functionality, and autonomic function in fibromyalgia syndrome (FMS).
- Trial name
- NCT06871306
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
Fibromyalgia, Myofascial Pain Syndrome
Auricular Vagus Nerve Stimulation For Fibromyalgia Syndrome
The purpose of this study is to evaluate the impact of auricular vagus nerve stimulation, applied in conjunction with an exercise treatment program, on pain and life quality in patients with Fibromyalgia Syndrome (FMS).
- Trial name
- NCT04260906
- Testing
- Vagus nerve stimulator, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bahçeşehir University