Clinical trials: Nervousness
Stroke, Hand Function
Development of a FES Device for Hand Use During Arm Activities Following Stroke
The goal of the study is to develop an individualized, synergy resistant, portable electromyographic (EMG)-driven functional electrical stimulation (FES) device that allows for Reliable and Intuitive control of hand (ReIn-Hand)…
- Trial name
- NCT03986216
- Testing
- ReIn-Hand device assisted home-based practice
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Northwestern University
Intracranial Bleed, Falls
Falls Validation Study
Each year, one in three adults over the age of 65 has a fall. These falls lead to half a million Canadian emergency department patient visits annually and falls in older adults account for more than 3% of all emergency department…
- Trial name
- NCT07536906
- Testing
- Clinical Decision Rule
- Where
- 7 sites in United States, Canada
- Volunteers
- 4,000 people
- Sponsor
- Dr. Kerstin de Wit
Anesthesia, Local, Nerve Pain
SEQ Block for Perioperative Analgesia in Acetabular Surgery
The study will evaluate ultrasound guided SEQ block: single puncture combined lumbar erector spinae plane block and paraspinous sagittal shift (PSSS) quadratus lumborum block when compared with conventional intravenous morphine…
- Conditions
- Anesthesia, Local, Nerve Pain, Pain, Postoperative, Acetabular Fracture
- Trial name
- NCT04688814
- Testing
- Single puncture combined lumbar erector spinae plane block and quadrates lumborum block, Morphine Sulfate
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Alexandria University
Epilepsy
Multicenter Trial for Adults With Partial Seizures
To compare seizure frequency in patients with refactory partial seizures (with or without generalization) who are taking Talampanel versus placebo as an add-on therapy to other licensed concomitant antiepileptic drugs (AEDs) and…
- Trial name
- NCT00034814
- Testing
- Talampanel
- Volunteers
- 190 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Sarcopenia
High Intensity Resistance Training and Possible Sarcopenia
Studies conducted so far added the dietary supplements along with resistance training as an intervention, we could not determine whether the observed effects of the intervention were due to the training program and/or dietary…
- Trial name
- NCT05985616
- Testing
- High Intensity Resistance Training
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Metabolism, Insulin Resistance
The Effect of Pharmacological Antilipolysis on the Metabolic Effects of Ghrelin
This study will investigate the non-growth-hormone-dependent metabolic effects of the hormone Ghrelin in growth hormone deficient subjects by examining the insulin tolerance as well as signal proteins in fat and muscle biopsies.
- Conditions
- Metabolism, Insulin Resistance, Hypopituitarism
- Trial name
- NCT01209416
- Testing
- Acipimox, Ghrelin
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- University of Aarhus
Neuropathy Small Fibre
Dorsal Root Ganglion Stimulation for the Management of Painful Intractable Small Fibre Neuropathy:
A prospective, single-arm, mono-centre pilot study to obtain preliminary information on the ability of Dorsal Root Ganglion Stimulation (DRGS) in alleviating the painful symptoms in patients with small fiber neuropathy (SFN).
- Trial name
- NSI-TD-002 (NCT02435004)
- Testing
- Spinal Modulation Axium™
- Where
- Switzerland
- Volunteers
- 31 people
- Sponsor
- Ospedale Regionale di Lugano
Virtual Reality, Anesthesia
HoloLens: an Objective Alternative to the Operator's Memory
Neuraxial anesthesia has traditionally been a 'blind' technique relying on users' feel and skill, both are subjective, lack complete accuracy and influenced by patient's physique variations that are quite challenging, and lead to…
- Conditions
- Virtual Reality, Anesthesia, Epidural
- Trial name
- Hololens (NCT04028284)
- Testing
- HoloLens-guided epidural, US-guided epidural
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer, Head and Neck Cancer
Using Traditional Acupuncture in the Management of Cancer Treatment Related Lymphoedema
RATIONALE: Acupuncture and moxibustion may improve well-being and quality of life in patients with lymphedema caused by breast cancer or head, neck, and throat cancer.
- Conditions
- Breast Cancer, Head and Neck Cancer, Lymphedema
- Trial name
- AMWELL-SL (NCT00828516)
- Testing
- Acupuncture and moxibustion
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- East and North Hertfordshire NHS Trust
Preventing Stroke in Sickle Cell Anaemia
Preventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Randomized Control Trial
Sickle cell anaemia (SCA) is a common hereditary haemoglobin disorder in Africa. World wide it is estimated that about 300,000 newborns are born every year. Of which 75% of them live in Sub-saharan Africa (SSA).
- Trial name
- PREST (NCT03666806)
- Testing
- Influenza vaccine
- Where
- Uganda
- Volunteers
- 150 people
- Sponsor
- Makerere University
Spinal Cord Injury
"Guarantee Assessment in Skin Prevention Adapted to Real Life With a Connected Device After a Spinal Cord Injury."
The investigators propose to test an embedded device on the seat of the wheelchair of paraplegic or tetraplegic patients (Gaspard), allowing on the one hand the continuous measurement of the pressures of seat, on the other hand a…
- Trial name
- GASPARD-SCI (NCT05403606)
- Testing
- GASPARD®
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Nantes University Hospital
Brain Tumors
Brain Areas of Time-To-Contact Perception: an Awake Surgery Study
During a brain surgery targeted to remove a brain tumor, the neurosurgeon wakes up the patient to delimit the tumor area exactly, and identify the surrounding areas, to limit the surgery damages.
- Trial name
- BRAIN-TIME (NCT04128306)
- Testing
- Behavioral task, Awake surgery, Neurological assessment
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Alzheimer's Disease
Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease
The purpose of this study is to test if the investigational medication ABT-089 is a safe and effective treatment for Alzheimer's disease.
- Trial name
- NCT00555204
- Testing
- ABT-089
- Where
- 42 sites in United States
- Volunteers
- 337 people
- Sponsor
- Abbott
Cancer, Myocarditis
Randomized Controlled Study Evaluating the Efficacy of Hypnosis in Nuclear Medicine
In Nuclear Medicine, the examinations are long (20-60 minutes) and the patients must remain immobile, sometimes fasting. The anxiety of the latter can lead to poor quality examinations and sometimes, although already injected…
- Conditions
- Cancer, Myocarditis, Alzheimer Disease, Parkinson
- Trial name
- HYDEM (NCT06116084)
- Testing
- Ericksonian Hypnosis, Hypnosis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Sleep Apnea, Obstructive
Tongue Advancement for Obstructive Sleep Apnea
The objective of this study is to assess the feasibility, safety and effectiveness of tongue stabilization using Aspire Medical Advance™ System for the treatment of obstructive sleep apnea (OSA).
- Trial name
- NCT00490984
- Testing
- Aspire Medical Advance System
- Where
- 3 sites in Belgium, Czechia and 1 more
- Volunteers
- 60 people
- Sponsor
- Aspire Medical
Primary Snoring, Sleep Apnea
Study Will Test the Theory That Training With the Facial-Flex Exercise Device Will Improve Snoring in Patients
The study will test the hypothesis that training with the Facial-Flex exercise device for six weeks will improve snoring in patients with primary snoring or very mild sleep apnea.
- Trial name
- NCT01554904
- Testing
- Facial-Flex
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Facial Concepts, Inc.
Mobility, Depressive Symptoms
Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People
In their day to day, persons do from simple to more or less complicated tasks and activities (ie: stand from a chair, open a door, shopping, read, drive, play chess, remind an appointment...).
- Conditions
- Mobility, Depressive Symptoms, Nutrition, Healthy, Cognitive Decline
- Trial name
- EFICIS (NCT05249504)
- Testing
- VIVIFRAIL, Nutrition, Psychology
- Volunteers
- 212 people
- Sponsor
- Fundacio Salut i Envelliment UAB
Amyotrophic Lateral Sclerosis
Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis
The preclinical rationale for tauroursodeoxycholic acid (TUDCA) use in treating patients with amyotrophic lateral sclerosis (ALS) stems from the demonstration of antioxidant, antiapoptotic and neuroprotective properties of TUDCA…
- Trial name
- TUDCA-ALS (NCT00877604)
- Testing
- tauroursodeoxycholic acid (TUDCA)
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Proximal Humeral Fracture, Anesthesia, Regional
Optimized Costoclavicular Block for Elderly Proximal Humeral Fracture Surgery
Background: Proximal humeral fractures are common in elderly patients and often require surgical fixation (open reduction and internal fixation).
- Conditions
- Proximal Humeral Fracture, Anesthesia, Regional, Diaphragmatic Paralysis
- Trial name
- OptCCB (NCT07612514)
- Testing
- Costoclavicular Brachial Plexus Block, Interscalene Brachial Plexus Block, Superficial Cervical Plexus Block
- Where
- 3 sites in China
- Sponsor
- Shanghai Tong Ren Hospital
Stroke, Traumatic Brain Injury
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
The aging population and its accompanying burden from non-communicable chronic diseases predicts an increasing impact imposed by frailty on healthcare systems.
- Conditions
- Stroke, Traumatic Brain Injury, Knee Osteoarthritis, Breast Cancer
- Trial name
- OPTIMA-C (NCT06073106)
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Tan Tock Seng Hospital
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