Clinical trials: Nervousness
Infant, Premature, Erythropoietin
High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study
The highest risk for perinatal brain injury occurs among extremely premature infants who weigh less than 1250 grams at birth. Such perinatal brain injury is currently irreversible, associated with neurodevelopmental disability…
- Conditions
- Infant, Premature, Erythropoietin, Brain Injury, Intraventricular Hemorrhage
- Trial name
- NCT00589953
- Testing
- Erythropoietin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Impulse Control Disorder, Parkinson Disease
Naltrexone for Impulse Control Disorders in Parkinson's Disease
This study will evaluate the effectiveness of naltrexone in reducing ICD symptoms in Parkinson's disease patients taking a dopamine agonist.
- Trial name
- NCT01052831
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Spatial Neglect, Hemispatial Neglect
A Model to Identify Specific Predictors of Spatial Neglect Recovery
This study examines methods to better predict improvement of a hidden disability of functional vision, spatial neglect, following stroke.
- Conditions
- Spatial Neglect, Hemispatial Neglect, Hemineglect, Unilateral Neglect
- Trial name
- NCT00990353
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Kessler Foundation
Deep Venous Thrombosis, Pulmonary Embolism
Drug Interaction Between Paracetamol and Warfarin
The objective of this study is to investigate whether paracetamol, given at therapeutic doses (2g/day and 3 g/day), may potentiate the anticoagulant effect of warfarin.
- Conditions
- Deep Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Stroke
- Trial name
- INPAWA2 (NCT01104337)
- Testing
- paracetamol
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Hopital Lariboisière
Tension-Type Headache
Effectiveness of Vagus Nerve Stimulation in Individuals With Tension-Type Headache
It is planned to examine the effect of Vagus Nerve Stimulation on headache symptoms in individuals with tension-type headache.
- Trial name
- NCT06604637
- Testing
- Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bitlis Eren University
Fragile X Syndrome
Study of SPG601 in Adult Men With Fragile X Syndrome
This Phase 2 study described herein will evaluate the safety, efficacy, tolerability, pharmacokinetics and pharmacodynamics of SPG601 in adult men with Fragile X syndrome.
- Trial name
- NCT06413537
- Testing
- SPG601
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Spinogenix
Insomnia
A Clinical Study to Evaluate the Pharmacokinetic Profile of SB-649868 in Elderly and Female Population
The purpose of this study is to determine the blood levels and the tolerability of SB-649868 in Elderly and Female population
- Trial name
- NCT00534872
- Testing
- SB-649868
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Recurrent Tonsillitis, Peritonsillar Abscess
Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain
The goal of this study is to assess the role of battlefield acupuncture in the reduction of pain scores status post adult tonsillectomy.
- Conditions
- Recurrent Tonsillitis, Peritonsillar Abscess, Obstructive Sleep Apnea
- Trial name
- NCT01790477
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Brain and Central Nervous System Tumors
Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00031577
- Testing
- paclitaxel, radiation therapy
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Children's Hospital of Philadelphia
Postural Orthostatic Tachycardia Syndrome, Chronic Orthostatic Intolerance
Using Mirabegron to Increase BP in Patients With POTS
This is a pilot dose-finding study to test the hypothesis that mirabegron increases systolic blood pressure (BP), prevents syncope/presyncope, and improves the quality of life (QOL), functional capacity, chest pain, and…
- Conditions
- Postural Orthostatic Tachycardia Syndrome, Chronic Orthostatic Intolerance, Syncope
- Trial name
- RAISE-BP (NCT06133075)
- Testing
- Mirabegron 50 MG, Mirabegron 25 MG
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Apnea, Sleep Disorders
A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)
This study is being done to learn about the safety and effects of a study medicine called berobenatide (bear-oh-BEN-uh-tide). The study will see if berobenatide can help adults with breathing problems during sleep (obstructive…
- Conditions
- Apnea, Sleep Disorders, Overweight and/or Obesity
- Trial name
- VESPER-OSA 2 (NCT07881757)
- Testing
- Berobenatide
- Where
- 2 sites in United States
- Volunteers
- 258 people
- Sponsor
- Pfizer
Obesity and Obesity-related Medical Conditions, Diabetes
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research…
- Conditions
- Obesity and Obesity-related Medical Conditions, Diabetes, Atherosclerotic Disease, Heart Failure
- Trial name
- VALD (NCT07083557)
- Testing
- Endothelial cell collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bettina Mittendorfer
Tinnitus
Tinnitus Related Cerebral Activities
The proposed research is to identify the brain areas activated or deactivated by tinnitus in humans. The identification of these areas is expected to be able to treat tinnitus refractory to traditional therapies by methods of…
- Trial name
- ACCELA (NCT02853812)
- Testing
- Functional brain MRI
- Volunteers
- 24 people
- Sponsor
- University Hospital, Montpellier
Atheroscleroses, Coronary, Atheroscleroses, Cerebral
Digital Secondary Prevention After Atherosclerotic Cardiovascular Disease
Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality worldwide and in Norway. Approximately 50% of the patients admitted to hospitals with an acute ASCVD event has had a previous…
- Conditions
- Atheroscleroses, Coronary, Atheroscleroses, Cerebral, Atherosclerotic Ischemic Disease
- Trial name
- NCT06738381
- Testing
- Digital intervention and motivational counselling
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Vestre Viken Hospital Trust
Postoperative Delirium
Manual vs Automated Anesthesia : Impact On The Incidence Of POCD
This study will be the first study to report the combined use of three independent closed-loop systems together to assist clinicians in titrating anesthesia, analgesia, fluid and optimize ventilation in frailty old patients…
- Trial name
- NCT03148730
- Testing
- closed-loop group
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Erasme University Hospital
Hypertension, Ischemic Heart Disease
A Morbidity-Mortality and Remodeling Study With Valsartan
The JIKEI HEART Study has been designed to investigate whether concomitant treatment with valsartan, an angiotensin II receptor blocker (ARB), in addition to conventional treatment, will improve the prognosis of 3000 Japanese…
- Conditions
- Hypertension, Ischemic Heart Disease, Congestive Heart Failure
- Trial name
- NCT00133328
- Testing
- valsartan
- Where
- Japan
- Volunteers
- 3,000 people
- Sponsor
- Jikei University School of Medicine
Insomnia
Sleep-MOMagement: Improving Postpartum Sleep in First-time Mothers Through Tailored Behavioral Approaches.
The goal of this clinical trial is to find out if person-centered behavioral interventions can help first-time mothers sleep better after childbirth.
- Trial name
- SleepMOM (NCT07345065)
- Testing
- Behavioural Sleep Managament, Behavioural Aerobic Exercise Therapy
- Where
- 2 sites in Belgium
- Volunteers
- 135 people
- Sponsor
- De deyne Manon
Relapsing Remitting Multiple Sclerosis
Effectiveness and Safety of Generic Delayed-Release Dimethyl Fumarate (Sclera® or Marovarex ®, Hikma) in Routine Medical Practice in the Treatment of Relapsing-Remitting Multiple Sclerosis in MENA Region
The purpose of this observational study is to evaluate the effectiveness, safety and health related quality of life of Generic DMF (Sclera® or Marovarex ®, Hikma) in patients undergoing routine clinical care for RRMS in MENA…
- Trial name
- NCT04468165
- Testing
- Dimethyl Fumarate (DMF)
- Where
- 6 sites in Algeria, Egypt and 1 more
- Volunteers
- 160 people
- Sponsor
- Hikma Pharmaceuticals LLC
Ischemic Stroke, Acute
A Multicenter Study Based on Multi-omics Analysis to Predict the Early Prognosis and Recurrence Risk of Acute Ischemic Stroke
Through a multicenter prospective AIS cohort study, we analyze the potential association of human proteome, microbiome and metabolome alterations with AIS prognosis, searching for key proteins, differential organisms and…
- Trial name
- NCT06584565
- Testing
- microbiome; metabolomics; proteomics
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Parkinson Disease
Pharmacokinetics of Levodopa/Carbidopa Infusion With and Without Oral Catechol-O-methyl Transferase (COMT) Inhibitors
The purpose of this study is to determine whether oral intake of COMT inhibitors affects the smooth plasma levodopa levels achieved by intestinal levodopa/carbidopa infusion in advanced Parkinson's disease patients.
- Trial name
- DuoCOMT (NCT00906828)
- Testing
- levodopa/carbidopa, entacapone, tolcapone
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Uppsala University
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