Clinical trials: Nervousness
Spastic Diplegia, Cerebral Palsy
Effect of Core Stability Training on Segmental Trunk Control and Quality of Life in Children with Cerebral Palsy
Spastic diplegia is a common shape of cerebral palsy that significantly affects trunk control and quality of life in children. Core stability training (CST) has been utilized as a potential intervention to improve the trunk…
- Trial name
- NCT06822296
- Testing
- Physical Therapy, Designed rehabilitation program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Infarction
Early Determinants of Multidimensional Outcome at School Age After Neonatal Arterial Ischemic Stroke
While perinatal ischemic stroke is the most frequent form of childhood stroke, early determinants of outcome remain poorly understood.
- Trial name
- NCT02511249
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Ischemic Stroke
Affect of Health Education on Statins Medication Persistence and ClinicaL Prognosis of Ischemic Stroke Patients (HELP)
The purpose of this study is to assess the affect of multiple health education interventions for statins medication Persistence and clinical prognosis of ischemic stroke patients at 3, 6 and 12 months.
- Trial name
- NCT02140658
- Testing
- multiple health education interventions, conventional health education
- Where
- China
- Volunteers
- 3,111 people
- Sponsor
- yongjun wang
Relapsing Multiple Sclerosis
A Study of Immune Phenotype Biomarkers in Patients With Relapsing Multiple Sclerosis (RMS) After Treatment With 0.5mg Fingolimod
A study of immune phenotype biomarkers in patients with Relapsing Multiple Sclerosis (RMS) after treatment with 0.5mg fingolimod
- Trial name
- FLUENT (NCT03257358)
- Testing
- Fingolimod
- Where
- 66 sites in United States
- Volunteers
- 382 people
- Sponsor
- Novartis Pharmaceuticals
Amyotrophic Lateral Sclerosis
Low Dose IL-2 in the Treatment of Immune-associated ALS Syndrome
The purpose of this study was to evaluate the efficacy and safety of low-dose IL-2 in the treatment of immunorelated ALS syndrome.
- Trial name
- NCT04952155
- Testing
- IL-2
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Peking University Third Hospital
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor
Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Conditions
- Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Chordoma, Kidney Cancer
- Trial name
- NCT00003926
- Testing
- amifostine trihydrate, busulfan, filgrastim
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Alzheimer's Disease
Online Caregiver Psychoeducation and Support for Alzheimer's
This study is piloting an internet-based intervention to provide support for caregivers of VA patients with Alzheimer's disease or related memory difficulties (ADRD).
- Trial name
- NCT00416078
- Testing
- caregiver website support, caregiver brief supportive phone calls
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- US Department of Veterans Affairs
Pain Management
MEC90 for Supra-inguinal Fascia Iliaca Block Performed Under Ultrasound Guidance in Arthroscopic Knee Surgery
In this study, the minimum effective concentration required for supra-inguinal fascia iliaca block applied in patients undergoing arthroscopic knee surgery is aimed.
- Trial name
- NCT05408585
- Testing
- Regional Anesthesia Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Samsun University
Acute Ischemic Stroke
Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
- Trial name
- LOMEVO (NCT05779215)
- Testing
- Visit at D90
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Spinal Cord Injury
Chronic Pain and Brain Activity in Spinal Cord Injury
This study compares five different procedures to see how they affect pain and brain activity. The procedures include neurofeedback, self-hypnosis training, meditation, and two different levels of transcranial direct current…
- Trial name
- NCT01012635
- Testing
- Hypnosis, Meditation, Neurofeedback training
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Washington
Neuropathic Pain, Peripheral Neuropathy
Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management
Compare Axon Therapy using transcutaneous magnetic stimulation (tMS) against conventional medical management in treating post-traumatic peripheral neuropathic pain (PTPNP).
- Trial name
- NCT04795635
- Testing
- CMM + Axon Therapy
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NeuraLace Medical, Inc.
Dental Anxiety, Inferior Alveolar Nerve
Reducing Pain During Dental Nerve Block Injections in Children
Title of Study: Effect of External Cooling and Vibration, Counterstimulation, and Needle Type on Pain, Physiological, and Behavioral Outcomes During Inferior Alveolar Nerve Block in Pediatric Patients Why was this study done? The…
- Conditions
- Dental Anxiety, Inferior Alveolar Nerve, Pain Management
- Trial name
- IANB (NCT07667725)
- Testing
- Buzzy Device, Counterstimulation, 30-Gauge Needle
- Where
- Iraq
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Hemifacial Paralysis, Bell Palsy
Electrical Stimulation to Improve Recovery After Peripheral Nerve Injury
After nerve injury and facial palsy, many patients have permanent muscle and sensory dysfunction. Electrical stimulation (ES) of injured nerves may speed up axon growth and improve recovery.
- Trial name
- NCT03996525
- Testing
- Electrical Stimulation
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- The Hospital for Sick Children
Stroke
Perceptual-motor Interaction to Improve Bimanual Coordination After Stroke
Significant difficulty in incorporating the weaker arm in daily activities after stroke is, in part, driven by difficulty in engaging both arms interactively in a coordinated manner.
- Trial name
- Bimanual (NCT03755076)
- Testing
- Perceptual cuing
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Rheumatoid Arthritis, Myositis
Rheumatoid Arthritis and Myositis Cohort
The primary objective of this research is to establish a well characterized clinical and longitudinal cohort for individuals with Rheumatoid Arthritis (RA) and Myositis to create a place to maintain blood, urine, stool specimens…
- Trial name
- NCT05627089
- Sponsor
- Attune Health Research, Inc.
Malignant Melanoma, Brain Metastases
E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS)
This is a Phase 1 study of E6201 plus dabrafenib for the treatment of CNS metastases in BRAF V600-mutated metastatic melanoma. A total of up to N=28-34 subjects with melanoma metastasized to the CNS will be included.
- Trial name
- NCT03332589
- Testing
- E6201, E6201 plus dabrafenib
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Spirita Oncology, LLC
Delirium, Older Patients
Delirium in Geriatric Hospital Single-bed and Multibed Rooms
To investigate whether single-bed rooms can prevent and reduce incidence and duration of delirium compared to multi-bed rooms in elderly patients admitted to a geriatric department.
- Conditions
- Delirium, Older Patients, Admittance to Single-bed Rooms or Multi-bed Rooms
- Trial name
- NCT03199768
- Where
- Denmark
- Volunteers
- 1,014 people
- Sponsor
- Aarhus University Hospital
Hyponatremia, Hyponatremic
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)
Hyponatremia is defined as sodium below the normal range of 135-145. Symptomatically, it can cause patients to experience a wide range of symptoms including lethargy, headache, nausea, vomiting and in severe cases coma and even…
- Conditions
- Hyponatremia, Hyponatremic, Pituitary Tumor, Pituitary
- Trial name
- DHAPS (NCT03636568)
- Testing
- Fluid Restricted Group
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Alzheimer's Disease, Pseudobulbar Affect (PBA)
Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's Disease
The primary objective of this study is to test the hypothesis that Nuedexta (20/10) administered orally will reduce Pseudobulbar Affect (PBA) frequency and severity (CNS-Lability Scale and PLACS), with satisfactory safety and…
- Trial name
- NCT01832350
- Testing
- Nuedexta (20/10)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Dementia
Dyadic Personalized Home-Based Activity Program for Mild-to-Moderate Dementia Patients Post-Discharge
This interventional study aims to evaluate the efficacy of a dyadic personalized home-based activity program in managing behavioral and psychological symptoms of dementia (BPSD) among home-dwelling people living with…
- Trial name
- NCT07081750
- Testing
- Dyadic personalized home-based activity program intervention, Routine care
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Fujian Medical University
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