Clinical trials: Neural Injury
Preterm Infant, BPD - Bronchopulmonary Dysplasia
Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA
Extubation failure is a significant problem in preterm neonates and prolonged intubation is a well-documented risk factor for development of chronic lung disease.
- Conditions
- Preterm Infant, BPD - Bronchopulmonary Dysplasia, Barotrauma
- Trial name
- NCT03242057
- Testing
- NAVA, NIPPV
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Injury of Other Nerves at Wrist and Hand Level of Unspecified Arm, Initial Encounter
Conversion of Seddon III Nerve Injury to Seddon I/II Nerve Injury
This study will evaluate the safety and efficacy of PEG 3350 for use in nerve repair.
- Trial name
- NCT03236064
- Testing
- Polyethylene Glycols
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- WellSpan Health
Posttraumatic Stress Disorder (PTSD)
Estradiol-mediated Neural Plasticity as Potential Mediator of Neurofeedback Treatment Change for Traumatized Women
Post-traumatic stress disorder (PTSD) is a common debilitating disorder that affects many individuals exposed to aversive events. The severity of PTSD symptoms is positively correlated with amygdala activation.
- Trial name
- NCT03416764
- Testing
- EFP-NF training
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder (PTSD)
Neural Correlates of Early Intervention for Posttraumatic Stress Disorder (PTSD)
Background: Innovation: Over 150,000 soldiers are currently deployed in Iraq as part of Operation Iraqi Freedom (OIF), and 12% of returning OIF veterans have posttraumatic stress disorder (PTSD).
- Trial name
- NCT00665678
- Testing
- paroxetine
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Foundation for Atlanta Veterans Education and Research, Inc.
Humeral Fractures
Management of Displaced Supracondylar Fractures of the Humerus Using Lateral vs. Crossed K-wires
Completely displaced (Type III) supracondylar fractures of the humerus are treated in the operating room and are held together with pins stuck into the bone. There are two ways of inserting the pins: crossed and laterally.
- Trial name
- NCT00358787
- Testing
- Crossed K-wiring of supracondylar fracture of the humerus, Lateral K-wiring of supracondylar fracture of the humerus
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of British Columbia
Reliability of Sensory Neurography and S2PD
Sensory Neurography and S2PD, a Test-Retest Study
This study was conducted as a test-retest investigation to assess the reliability of the methods prior to a planned study on the same topic.
- Trial name
- NCT07605585
- Testing
- S2PD, Sensory neurography
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
PTSD
Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder
The purpose of this study was to assess the effects of the medication paroxetine on symptoms of posttraumatic stress disorder (PTSD) and the brain in women with a history of PTSD related to childhood abuse.
- Trial name
- NCT01681849
- Testing
- Paroxetine, Positron Emission Tomography (PET) Imaging
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Emory University
Anorexia Nervosa, Major Depressive Disorder
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or…
- Conditions
- Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT02615119
- Testing
- Isoproterenol, Normal saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Traumatic Injury, Peroneal Nerve Injury
Peroneal Nerve Injury: a 20- Year Retrospective Case Series Study
In a 20-year retrospective study, all skiers and snowboarders with a peroneal nerve injury at the fibular head treated surgically at the Department of Plastic, Reconstructive and Aesthetic Surgery at the Medical University of…
- Conditions
- Traumatic Injury, Peroneal Nerve Injury, Sport Injury
- Trial name
- NCT04980937
- Testing
- Microsurgical reconstruction of peroneal nerve with or w/o nerve grafts.
- Volunteers
- 34 people
- Sponsor
- Medical University Innsbruck
Carpal Tunnel Syndrome
Oral Gabapentin and Median Nerve Mobilization in the Treatment of Carpal Tunnel Syndrome
The present randomized clinical trial will perform a comparison of the pain reduction effects produced by the application of a non invasive and non pharmacological median nerve neural mobilization (physiotherapy treatment), to…
- Trial name
- NCT04285281
- Testing
- Gabapentin oral capsules, Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 126 people
- Sponsor
- Universidad Europea de Madrid
Peripheral Nerve Injury Upper Limb
Reconstruction of Digital Nerve Lesions With Muscle-in-Vein Conduits
Muscle-in-vein conduits (MVCs) provide an alternative for bridging digital nerve defects when tension-free suture is not possible.
- Trial name
- NCT04788030
- Testing
- Nerve reconstruction
- Volunteers
- 37 people
- Sponsor
- BG Trauma Center Tuebingen
Head Injury, Minor, Concussion, Mild
Heading in Football: Impact on Neural Blood Biomarkers
The goal of this observational study is to evaluate the safety of heading in football. We will study the release of biomarkers in blood that reflect microscopic neural damage.
- Conditions
- Head Injury, Minor, Concussion, Mild, CTE - Chronic Traumatic Encephalopathy, Neurodegeneration
- Trial name
- HEADLINE (NCT06147596)
- Testing
- Head impact exposure
- Where
- Netherlands
- Volunteers
- 335 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ulnar Neuropathies
The Effect of Ulnar Nerve Injury Localization on Sleep Quality in Patients With Ulnar Nerve Entrapment Neuropathy
Regardless of the cause of ulnar nerve entrapment neuropathy, we are planning to investigate the relationship between sleep quality disorder that may develop due to ulnar neuropathy and the level of entrapment in…
- Trial name
- NCT05177861
- Testing
- EMG
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Yuzuncu Yil University
Muscle Injury, Nerve Injury
Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer
Foot drop deformity is a life limiting condition characterized by loss of ankle dorsiflexion and eversion. Main condition leading to drop foot condition include irrecoverable muscle and nerve injuries, poliomyelitis, drug…
- Conditions
- Muscle Injury, Nerve Injury, Poliomyelitis, Leprosy
- Trial name
- NCT01751503
- Testing
- Interosseous route of TPTT, Extra membranous route of TPTT
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Iva Hauptmannova
Spinal Cord Injuries, Spina Bifida
Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical Disabilities
Participation in community-based activities is essential to the health and well-being of youth with physical disabilities; yet, it is extremely restricted.
- Conditions
- Spinal Cord Injuries, Spina Bifida, Musculoskeletal Disorder, Juvenile Arthritis
- Trial name
- NCT05784285
- Testing
- Engagement in a 8-week community-based activity program
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- McGill University