Clinical trials: Neuralgia,Postherpetic
Diabetic Neuropathies, Herpes Zoster
Dextromethorphan Versus Placebo for Neuropathic Pain
In our current clinical trial, we are comparing the effects of two NMDA receptor antagonists to placebo in patients with painful distal symmetrical diabetic neuropathy or post-herpetic neuralgia.
- Conditions
- Diabetic Neuropathies, Herpes Zoster, Neuralgia
- Trial name
- NCT00001344
- Testing
- dextromethorphan
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Postherpetic Neuralgia, Diabetic Polyneuropathies
Botulinum Toxin in Peripheral Neuropathic Pain
Pain due to peripheral nerve lesion remains extremely difficult to treat and current treatments have onl moderate efficacy and/or side effects.
- Conditions
- Postherpetic Neuralgia, Diabetic Polyneuropathies, Other Polyneuropathies
- Trial name
- NCT01251211
- Testing
- botulinum toxin type A
- Where
- 3 sites in Brazil, France
- Volunteers
- 66 people
- Sponsor
- Hospital Ambroise Paré Paris
Neuralgia, Postherpetic
Efficacy, Safety and Tolerability Study of TAK-583 in Subjects With Postherpetic Neuralgia
The purpose of this study is to evaluate the efficacy of TAK-583, once daily (QD), in relieving pain in subjects with postherpetic neuralgia.
- Trial name
- NCT00377598
- Testing
- TAK-583
- Where
- 48 sites in Australia, Bulgaria and 7 more
- Volunteers
- 399 people
- Sponsor
- Takeda
Postherpetic Neuralgia
Efficacy and Safety Study of SLC022 in Treating Pain Associated With Post Herpetic Neuralgia
The purpose of this study is to evaluate the efficacy and safety of SLC022 in treating pain associated with post-herpetic neuralgia (PHN) in recently diagnosed patients.
- Trial name
- NCT00813826
- Testing
- SLC022
- Where
- 19 sites in United States
- Volunteers
- 204 people
- Sponsor
- Solace Pharmaceuticals
Postherpetic Neuralgia
A Study To Compare Pregabalin/PF-00489791 Combination Versus Pregabalin Alone In Post-Herpetic Neuralgia
Pregabalin is an alpha-2 delta ligand approved for the treatment of neuropathic pain, however, not all patients will respond to this drug.
- Trial name
- NCT00599638
- Testing
- pregabalin, pregabalin/PF-00489791
- Where
- 39 sites in United States
- Volunteers
- 72 people
- Sponsor
- Pfizer
Postherpetic Neuralgia, Neuropathic Pain
Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic Neuralgia
This observational study aims to compare the effectiveness of ultrasound-guided erector spinae plane (ESP) block and transcutaneous radiofrequency (RF) treatment in patients with postherpetic neuralgia.
- Conditions
- Postherpetic Neuralgia, Neuropathic Pain, Herpes Zoster
- Trial name
- NCT07400640
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Neuralgia, Postherpetic
A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN)
The purpose of this study is to determine whether gabapentin enacarbil (XP13512/GSK1838262), hereafter referred to as GEn is effective in the treatment of neuropathic pain associated with post-herpetic neuralgia (PHN).
- Trial name
- NCT00619476
- Testing
- GEn 1200mg/day, GEn 2400mg/day, GEn 3600mg/day
- Where
- 83 sites in United States, Canada
- Volunteers
- 376 people
- Sponsor
- XenoPort, Inc.
Postherpetic Neuralgia
A Study of ONO-1110 in Patients With Postherpetic Neuralgia
To evaluate the efficacy and safety of ONO-1110 in Japanese patients with postherpetic neuralgia
- Trial name
- NCT06708416
- Testing
- ONO-1110
- Where
- 31 sites in Japan
- Volunteers
- 142 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Postherpetic Neuralgia
Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia
The purpose of this study is to determine whether KAI-1678 is effective in the treatment of postherpetic neuralgia pain
- Trial name
- NCT01106716
- Testing
- KAI-1678, Lidocaine
- Where
- Australia
- Volunteers
- 23 people
- Sponsor
- KAI Pharmaceuticals
Post Herpetic Neuralgia
Phase IV Study of FDA Approved, Once-Daily GRALISE™(Gabapentin) Tablets for the Treatment of Postherpetic Neuralgia
Study objective is to assess the safety and effectiveness of once- daily GRALISE in clinical practice
- Trial name
- NCT01426230
- Where
- 37 sites in United States
- Volunteers
- 201 people
- Sponsor
- Depomed
Herpes Zoster
A Study to Assess the Burden of Herpes Zoster and Postherpetic Neuralgia in Japanese Adults Aged Sixty Years and Above
The study aims to estimate the incidence of herpes zoster (HZ), proportion of postherpetic neuralgia (PHN) and the economic burden and impact on quality of life, in Japanese adults greater than or equal to sixty years of age.
- Trial name
- NCT01873365
- Testing
- Data collection
- Where
- 14 sites in Japan
- Volunteers
- 448 people
- Sponsor
- GlaxoSmithKline
Neuralgia
Evaluating E2007 (Perampanel) in Patients With Painful Diabetic Neuropathy (PDN) or Post-Herpetic Neuralgia (PHN)
The purpose of this study is to evaluate the safety, tolerability and continued efficacy of perampanel in patients previously enrolled in double-blind, placebo-controlled studies for Painful Diabetic Neuropathy (PDN) or…
- Trial name
- NCT00592904
- Testing
- E2007
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Eisai Inc.
Neuralgia, Herpes Zoster
Development of a Bedside Pain Assessment Kit for Postherpetic Neuralgia
Post herpetic neuralgia (PHN) is an undertreated condition. It is a type of neuropathic pain (NP), or pain caused by abnormal activity of sensory nerves.
- Trial name
- BSTK (NCT01166295)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Analgesic Solutions
Neuropathic Pain, Postherpetic Neuralgia
Simultaneous Engagement of Networks for Alleviating Pain (SENAP)
This trial is investigating the acceptability and efficacy of PFM-guided cortical stimulation for the treatment of central neuropathic pain.
- Trial name
- NCT07057206
- Testing
- PFM-guided cortical stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Neuralgia
A Study to Assess the Safety and Efficacy of 7 Days Treatment With a Novel Analgesic in Subjects With Peripheral Neuropathic Pain
The purpose of this trial is to determine whether a novel analgesic is effective in treating of neuropathic pain caused by herpetic infection, surgery, or trauma.
- Trial name
- NCT01485094
- Testing
- GRT6010, Pregabalin
- Where
- 12 sites in Germany, Hungary and 2 more
- Volunteers
- 114 people
- Sponsor
- Grünenthal GmbH
Depression Disorders, Herpetic Neuralgia
Ketamine for Postherpetic Neuralgia With Depression
This clinical trial examines the antidepressant efficacy and safety of a single low-dose intravenous esketamine combined with oral duloxetine in patients with postherpetic neuralgia and depression (duration more than 1 month).
- Trial name
- NCT06968624
- Testing
- Intravenous Ketamine Infusions, Intravenous normal saline, Oral Duloxetine 60mg
- Volunteers
- 50 people
- Sponsor
- Huazhong University of Science and Technology
Diabetic Neuropathy, Neuropathic Pain
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Neuralgia, Postherpetic
- Trial name
- PRISE (NCT07712913)
- Testing
- Experimental: Pregabalin XR, Comparator: Dorene Tabs
- Where
- 15 sites in Brazil
- Volunteers
- 348 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Postherpetic Neuralgia, Y-4
Y-4 to Treat the Postherpetic Neuralgia
The goal of this clinical trial is to assess the efficacy and safety of Y-4 in patients with postherpetic neuralgia(PHN). The main questions it aims to answer are: The efficacy and safety of Y-4 to treat PHN compared with…
- Conditions
- Postherpetic Neuralgia, Y-4, Pregabalin
- Trial name
- NCT07275762
- Testing
- Y-4 tables, Pregabalin
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Pain
[S,S]-Reboxetine Long Term Safety Study In Post-Shingles Pain.
The purpose of this study is to assess the long term (up to 2 years) safety and tolerability of [S,S]-Reboxetine in patients with pain after shingles.
- Trial name
- NCT00354094
- Testing
- [S,S]-Reboxetine
- Where
- 40 sites in United States, Argentina and 10 more
- Volunteers
- 600 people
- Sponsor
- Pfizer
Postherpetic Neuralgia, Infrared Thermal Imaging
Correlation Between Thermal Patterns of Infrared Thermal Imaging and Clinical Phenotype in Patients With Postherpetic Neuralgia
Postherpetic neuralgia (PHN) is the most frequent complication of herpes zoster(HZ) and is defined as pain persisting for >1month after the healing of herpetic skin lesion or pain persisting for > 3 months following the onset of…
- Trial name
- NCT05568186
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Xianwei Zhang,MD