Clinical trials: Neuralgia
HIV Infections, Peripheral Neuropathy
Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy
Study to determine if pregabalin is more effective than placebo in treating subjects with nerve pain associated with HIV neuropathy.
- Trial name
- NCT00232141
- Testing
- pregabalin
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 302 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Spinal Cord Injuries
Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury
Spinal cord injury (SCI) is associated with severe neuropathic pain that is often refractory to all pharmacological intervention.
- Trial name
- NCT04379011
- Testing
- Brivaracetam
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Painful Diabetic Peripheral Neuropathy
Ricolinostat in Patients With Painful Diabetic Peripheral Neuropathy
This is a randomized, double-blind, 2-arm, parallel group study of up to 274 evaluable patients designed to evaluate the safety and efficacy of the histone deacetylase 6 (HDAC6) inhibitor ricolinostat for painful DPN.
- Trial name
- NCT03176472
- Testing
- ricolinostat
- Where
- 35 sites in United States
- Volunteers
- 282 people
- Sponsor
- Regenacy Pharmaceuticals LLC
Diabetic Peripheral Neuropathy
Treatment of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the safety, tolerability and effectiveness of DS-5565 compared to placebo (inactive substance) and pregabalin in diabetic subjects with DPN.
- Trial name
- NCT01496365
- Testing
- DS-5565 tablet, pregabalin capsule
- Where
- 78 sites in United States
- Volunteers
- 452 people
- Sponsor
- Daiichi Sankyo
Hallux Valgus and Bunion (Disorder), Morton Neuroma
Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Foot surgery is a painful surgery that is usually scheduled in outpatients. A good management of analgesia is the crucial point.
- Conditions
- Hallux Valgus and Bunion (Disorder), Morton Neuroma, Metatarsal Fracture, Ingrown Nail
- Trial name
- DISTIB (NCT03504462)
- Testing
- Specific block of medial and lateral plantar nerves
- Where
- France
- Volunteers
- 27 people
- Sponsor
- CMC Ambroise Paré
Peripheral Nervous System Diseases, Chronic Pain
Chronic Neuropathy Following Chemotherapy
This is a clinical study which is a follow-up of a previous prospective questionnaire study. All patients who previously participated in the study will receive a new questionnaire and will be invited for a clinical examination.
- Trial name
- DOLORISKCIPN (NCT02654691)
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- Danish Pain Research Center
Central Neuropathic Pain
Study of Mirogabalin for Central Neuropathic Pain
Investigate the efficacy and safety of mirogabalin in participants with central neuropathic pain in comparison to placebo
- Trial name
- NCT03901352
- Testing
- Mirogabalin
- Where
- 118 sites in Japan, South Korea and 1 more
- Volunteers
- 300 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Chronic Pain Syndrome
Post-reimbursement Study to Follow Spinal Neurostimulator Devices for Pain Therapy (French SCS Registry)
Observational study to evaluate the long term efficacy of Spinal Cord Stimulation (SCS) over 2 years following SCS implant. This study is requested by French Health Authorities for reimbursement renewal, to maintain reimbursement…
- Trial name
- SME (NCT01778426)
- Where
- France
- Volunteers
- 414 people
- Sponsor
- MedtronicNeuro
Epilepsy, Neuropathic Pain
Lyrica (Pregabalin) Korean Post Marketing Surveillance Study
This study collects post-marketing safety and efficacy surveillance data in real world clinical use of pregabalin for its approved indications in Korea.
- Conditions
- Epilepsy, Neuropathic Pain, Fibromyalgia, Post-market Surveillance
- Trial name
- NCT01220180
- Testing
- pregabalin (Lyrica)
- Volunteers
- 4,175 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain, Peripheral Neuropathy
A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia
The purpose of this study is to evaluate the efficacy of Sativex® compared with placebo in relieving peripheral neuropathic pain associated with allodynia.
- Trial name
- NCT00710554
- Testing
- Sativex
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- Jazz Pharmaceuticals
Neuralgia, Postherpetic
A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia
The purpose of this study is to evaluate efficacy and safety of pregabalin in the treatment of postherpetic neuralgia in a dose-ranging manner.
- Trial name
- NCT00394901
- Testing
- Pregabalin
- Where
- 39 sites in Japan
- Volunteers
- 372 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuropathic Pain, Mechanical Hypersensitivity
AZD2066 Neuropathic Pain - Mechanical Hypersensitivity
The purpose of this study is to investigate if 28 days of treatment with AZD2066 compared to placebo can relieve the pain arising from the nervous system when the patients are touched by something that should not cause pain or…
- Trial name
- NP-MH (NCT00939094)
- Testing
- AZD2066
- Where
- 38 sites in United States
- Volunteers
- 87 people
- Sponsor
- AstraZeneca
Restless Legs Syndrome, Neuropathic Pain
Spinal Cord Stimulation for Restless Legs Syndrome
The overall goal of this proposed study is to evaluate the underlying mechanisms of neural control of blood flow in the lower extremities in humans with restless leg syndrome (RLS).
- Trial name
- NCT03539081
- Testing
- Dual-energy X-ray absorptiometry Scan, Laboratory Measurements, Blood Flow Measurement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marshall Holland
Chronic Neuropathic Pain in the Low Back and Legs
Field Shape and Amplitude Sensitivity Exploratory Study (CONTOUR Study)
The study aims to better understand how to program Spinal Cord Stimulation for the treatment of chronic low back and leg pain
- Trial name
- NCT02916498
- Testing
- Boston Scientific's Precision SPECTRA™ Spinal Cord Stimulation System
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Boston Scientific Corporation
Post Herpetic Neuralgia
Eslicarbazepine Acetate as Therapy in Post-Herpetic Neuralgia
The primary objective of this study is to assess the efficacy of Eslicarbazepine acetate (ESL) as therapy in subjects with Post-herpetic Neuralgia (PHN) over a 15 week treatment phase.
- Trial name
- NCT01124097
- Testing
- Eslicarbazepine acetate (BIA 2-093)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- Bial - Portela C S.A.
Neuropathic Pain, Chronic Pain
Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis
This study will determine whether treatment with an extended-release opioid or topical lidocaine is effective in relieving distal symmetric lower extremity burning pain associated with multiple sclerosis (MS).
- Conditions
- Neuropathic Pain, Chronic Pain, Multiple Sclerosis
- Trial name
- NCT00414453
- Testing
- Lidocaine patch 5%, Extended-release oxycodone
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Rochester
Neuropathic Pain
Efficacy of Intrathecal Oxytocin in Patients With Neuropathic Pain
The purpose of the study is to determine the effect of oxytocin given into the spinal fluid on pain and areas and intensity of hyperalgesia and allodynia in patients with chronic neuropathic pain.
- Trial name
- NCT02100956
- Testing
- oxytocin 100 micrograms, Normal Saline (preservative free)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Peripheral Neuropathy, Neuralgia
A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy
This is a multicenter, randomized, placebo-controlled, parallel group study of EpiCept™ NP-1 Topical Cream (amitriptyline 4%/ketamine 2%) in approximately 200 patients with pain in the lower extremities due to diabetic nerve pain.
- Trial name
- NCT00476151
- Testing
- EpiCept NP-1 (4% Amitriptyline/ 2% Ketamine) Topical Cream
- Where
- India
- Volunteers
- 226 people
- Sponsor
- EpiCept Corporation
Diabetic Neuropathy, Painful
An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain
To test the non-inferiority of duloxetine monotherapy as a treatment for the management of diabetic peripheral neuropathic pain as compared to pregabalin treatment among patients who have not had an adequate response to…
- Trial name
- NCT00385671
- Testing
- duloxetine hydrochloride, pregabalin, gabapentin
- Where
- 9 sites in United States, Germany
- Volunteers
- 407 people
- Sponsor
- Eli Lilly and Company
Neuropathic Pain, Postmastectomy Pain
Symptom Management After Breast Cancer Surgery
This trial is part of a larger, longitudinal study of symptoms that occur in the breast surgical scar area and/or ipsilateral arm following breast cancer surgery.
- Trial name
- NCT00686127
- Testing
- Lidoderm patch
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, San Francisco