Clinical trials: Neuralgia Peripheral
Phantom Limb Pain, Stump Neuralgia
Cryolesion in Treatment of Phantom Limb Pain
Assessment of pain intensity on the NRS. Assessment of the quality of life by SF-36 and AIS. Diagnostic/prognostic nerve block with 5 ml of 2% lidocaine under real-time ultrasound control with confirmation of the correct position…
- Conditions
- Phantom Limb Pain, Stump Neuralgia, Pain, Phantom
- Trial name
- NCT03415360
- Testing
- cryoablation
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Military Institute od Medicine National Research Institute
Morton Neuroma
Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma
Morton's neuroma is a benign thickening involving the plantar interdigital nerve, most common in middle aged women. Morton's neuroma is one of the most frequent diagnoses seen in the investigators podiatry clinic and is difficult…
- Trial name
- NCT05501262
- Testing
- Cryoablation, Nerve block
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Neuropathic Pain
Intrathecal Baclofen (ITB) Bolus on Neuropathic Pain (NP). Preliminary Study.
Hypothesis: ITB bolus can have antinociceptive effect on neuropathic pain in spinal cord injury patients, which could depend on the subtype of pain, or on the lesion level, cervical or thoracic spinal cord injury.
- Trial name
- ITB (NCT02705950)
- Testing
- Intrathecal baclofen bolus
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Institut Guttmann
Neuropathic Pain
Development of Stimulator Pneumatic for Realization of Evoked Potential Allodynic/Somatosensory
The stimuli used in the evoked potentials are electrical or laser. They are started and synchronized with the collection of the EEG by signals TTL (transistor-transistor logic).
- Trial name
- STIMEA (NCT02527590)
- Testing
- pneumatic stimulations(allodynic area), pneumatic stimulations (healthy area), pneumatic stimulations no auditory masking
- Where
- France
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Persistent Pain After Breast Cancer Surgery
Ultrasound Guided Pectoral Nerves Blockade for Persistent Pain After Breast Cancer Surgery
This is a pilot study of the pectoral nerves block (PECS) in patients with persistent pain after breast cancer surgery.
- Trial name
- PPBCS (NCT02349581)
- Testing
- PECS block, Bupivacaine
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy
Trial Investigating the Characteristics of Knismesis - a Lever to Explore Allodynia in Neuropathic Pain
Also known as a "moving itch", knismesis is a mildly annoying sensation caused by a light movement on the skin, such as from a crawling insect. Its underlying mechanism rely on spatial summation, i.e.
- Trial name
- TICKLE (NCT04621747)
- Testing
- Battery of neurophysiological explorations
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain, Peripheral Neuropathy
Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management
Compare Axon Therapy using transcutaneous magnetic stimulation (tMS) against conventional medical management in treating post-traumatic peripheral neuropathic pain (PTPNP).
- Trial name
- NCT04795635
- Testing
- CMM + Axon Therapy
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NeuraLace Medical, Inc.
Sciatica Due to Intervertebral Disc Disorder, Intervertebral Disc Displacement
Observational Study on Effectiveness and Safety of Integrative Korean Medicine Treatment for Inpatients With Sciatica Due to Lumbar Intervertebral Disc Herniation
Observational study on the effectiveness and safety of integrative Korean medicine treatment for inpatients with sciatica due to lumbar intervertebral disc herniation
- Conditions
- Sciatica Due to Intervertebral Disc Disorder, Intervertebral Disc Displacement, Sciatica, Sciatic Radiculopathy
- Trial name
- NCT03750591
- Testing
- Herbal medicine, Chuna manual therapy, Bee venom pharmacopuncture
- Where
- 4 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Jaseng Medical Foundation
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Neuralgia, Postherpetic
Effect of Opioids in Neuropathic Pain in Postherpetic Patients
Postherpetic neuralgia (PHN) is often associated with pain and sensory changes and is the leading type of neuropathic pain in modern clinical pain research.
- Trial name
- VHPRG-HDRPH (NCT01102101)
- Testing
- Remifentanil
- Where
- 2 sites in Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Lumbar Radiculopathy
Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain
This is a Phase I/II, double-blind, parallel-group, randomized, placebo-controlled multi-centre trial in 180 patients randomized 1:1:1 to receive the IMP (Dexamethasone acetate microspheres for extended-release injectable…
- Trial name
- SALIENT (NCT03952377)
- Testing
- SX600
- Where
- 10 sites in Australia
- Volunteers
- 56 people
- Sponsor
- SpineThera Australia PTY LTD
Neuropathic Pain, Chronic Pain
Insula Neuromodulation for Chronic Neuropathic Pain
This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.
- Trial name
- NCT05404581
- Testing
- neuromodulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Chronic Pain, Migraine Disability
Chronic Pain in the General Population of Chile
The present study seeks to follow up the cohort of adults representative of Chile's urban population whose levels of chronic pain were evaluated in March 2023 (baseline) as part of the Mental Health Thermometer (MHT) study.
- Conditions
- Chronic Pain, Migraine Disability, Neuropathic Pain, Fibromyalgia
- Trial name
- RDC (NCT06353100)
- Where
- Chile
- Volunteers
- 2,365 people
- Sponsor
- Pontificia Universidad Catolica de Chile
HIV Associated Polyneuropathy
Auricular Vagus Nerve Stimulation Mechanisms for HIV-Associated Peripheral Neuropathy
This study looks at a non-invasive ear stimulation treatment to better understand nerve pain in people living with HIV. The study aims to assess how the body and nervous system respond to this treatment, including changes in…
- Trial name
- NCT07822932
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (AVNS)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Miami
Neuropathic Pain, Pain
Optimized Programming in Spinal Cord Stimulation (SCS) System
The objective of this study is to evaluate extent, location, and perception of paresthesia as a function of anode/cathode configuration.
- Trial name
- OP (NCT00871819)
- Testing
- Precision Spinal Cord Stimulation (SCS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Type 2 Diabetes Mellitus, Painful Diabetic Peripheral Neuropathy (PDPN)
The Therapeutic Effects of Ceylon Cinnamon Supplementation and a Self-Efficacy Educational Program on Glycemic Control, Lipid Profiles, and Pain in Type 2 Diabetes Mellitus With Painful Diabetic Peripheral Neuropathy
This randomized controlled trial aims to evaluate the therapeutic effects of pure Ceylon cinnamon (Cinnamomum verum) supplementation combined with a structured self-efficacy-based educational program on glycemic control, lipid…
- Trial name
- Ceylon-EDU-RCT (NCT07757399)
- Testing
- Ceylon Cinnamon (Cinnamomum verum) Supplement, Self-Efficacy-Based Educational Program
- Volunteers
- 900 people
- Sponsor
- Jerash Private University
Cancer, Neuralgia
Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer
Rationale: Often, incurable cancer patients suffer from severe symptoms as (neuropathic) pain and fatigue with polypharmaceutic interventions as a consequence.
- Trial name
- Off-label (NCT00740571)
- Testing
- amitriptyline, pregabalin
- Where
- 2 sites in Netherlands
- Volunteers
- 130 people
- Sponsor
- Radboud University Medical Center
Pain, Diabetic Neuropathies
Safety and Efficacy of GRT6005 in Pain Due to Diabetic Polyneuropathy
The purpose of this trial is to investigate the efficacy and safety of GRT6005 in patients with painful diabetic neuropathy.
- Trial name
- NCT01347671
- Testing
- GRT6005
- Where
- 22 sites in Bulgaria, Germany and 1 more
- Volunteers
- 189 people
- Sponsor
- Tris Pharma, Inc.
Sciatica
Effects of Control Scan for Presumed Difficult Epidural Infiltrations (ECHORACHIS)
The aim of this care protocol is to study the effects of scan to help epidural infiltration realization, in presumed difficult patients suffering from sciatica.
- Trial name
- ECHORACHIS (NCT01832844)
- Testing
- Group " with scan prior to infiltration ", Group " without scan "
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Neuralgia, Epilepsy
Clinical Study With Lyrica In Patients Suffering From Epilepsy
Clinical study with Lyrica (pregabalin) in patients suffering from epilepsy. This drug is used as adjunctive therapy with one or more antiepileptics. Lyrica has potential to reduce seizure frequency.
- Trial name
- NCT00922987
- Testing
- Lyrica (pregabalin)
- Where
- 61 sites in Slovakia
- Volunteers
- 286 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
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