Clinical trials: Neuralgia Peripheral
Postoperative Pain, Neuropathic Pain
Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement
Spinal surgery is associated with intense pain and associated to a history of preoperative chronic pain. Pregabalin is licensed to treat chronic neuropathic pain, particularly when high dose of opioid are required.
- Trial name
- PREGAB (NCT02866396)
- Testing
- Pregabalin, Naive patient
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Christophe Aveline, MD
Chronic Neuropathic Pain
Surgical Treatment of Chronic Neuropathic Pain
Observational registry study assessing the subject's pain history and the impact of surgery for the treatment of chronic neuropathic pain by comparing post-operative outcomes (pain level, pain medication usage, quality of life…
- Trial name
- Rethink Pain (NCT04287075)
- Testing
- Surgical Management of Neuroma
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Axogen Corporation
Chronic Pain
The Effectiveness of Continuous Ketamine Infusion (KONTINUE)
There are different treatment for chronic pain. One possible treatment is intravenous infusions of ketamine.
- Trial name
- KONTINUE (NCT06131970)
- Where
- Monaco
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Princesse Grace
Nerve Pain, Shoulder Pain
The Effect of Dexmedetomidine on Brachial Plexus Block for Shoulder Surgery
The purpose of this study is to determine whether a small dose of Dexmedetomidine, when given either intravenously or as part of the interscalene nerve block solution, prolongs pain relief following shoulder surgery compared to…
- Trial name
- DEX (NCT02225054)
- Testing
- Dexmedetomidine, Ropivacaine, Normal Saline
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Women's College Hospital
Chronic Pain, Sciatica
NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators
The primary objective is to demonstrate the safety and efficacy of a non-awake implantation method (EMG neuromonitoring) of a SCS paddle lead as compared to an awake implantation method (with local anesthesia and patient…
- Conditions
- Chronic Pain, Sciatica, Failed Back Surgery Syndrome
- Trial name
- NAPS (NCT02284542)
- Testing
- Awake, Non-Awake
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- St. Luke's Hospital, Pennsylvania
Herniated Disk Lumbar
Return to Work After Early Intervention for Lumbar Disc Herniation Versus Usual Care
The most common cause of low back pain with radiculopathy among the working population is a Lumbar Disc Herniation (LDH). In general, the natural history of sciatica is favourable with spontaneous remission.
- Trial name
- WILD (NCT04657354)
- Testing
- Assessment
- Sponsor
- Spine Centre of Southern Denmark
Peripheral Nervous System Diseases, Pain
Study of NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is to assess the efficacy and safety of NGX-4010 applied for 60 minutes for the treatment of postherpetic neuralgia (PHN).
- Conditions
- Peripheral Nervous System Diseases, Pain, Neuralgia, Herpes Zoster
- Trial name
- NCT00115310
- Testing
- NGX-4010
- Volunteers
- 400 people
- Sponsor
- NeurogesX
Postherpetic Neuralgia
To Evaluate the Efficacy and Safety of SR419 in Patients With Postherpetic Neuralgia (PHN)
This is a Phase II, international multicenter, double-blind, placebo-controlled, crossover study to assess the efficacy of SR419 in PHN subjects.
- Trial name
- NCT05357677
- Testing
- SR419
- Where
- 13 sites in Australia, China
- Volunteers
- 83 people
- Sponsor
- Shanghai SIMR Biotechnology Co., Ltd.
Postherpetic Neuralgia, Esketamine
The Study on the Esketamine in the Treatment of Postherpetic Neuralgia
Herpes zoster (HZ) is an acute herpetic skin disease caused by the reactivation of the varicella-zoster virus (VZV) latent in the sensory ganglia.
- Trial name
- NCT04664530
- Testing
- esketamine, Saline
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neuropathy, Peripheral Neuropathy
Study of Nicotine for Pain Associated With Chemotherapy-Induced Peripheral Neuropathy
Assess the efficacy of short-term nicotine transdermal patch administration for the treatment of chemotherapy-induced peripheral neuropathy (CIPN) in cancer stable patients or patients in remission.
- Conditions
- Neuropathy, Peripheral Neuropathy, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
- Trial name
- NCT04468230
- Testing
- Nicotine Transdermal Patch
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
Neuralgia, Peripheral Neuropathic Pain
Randomized Controlled Trial of Efficacy and Safety of Local Anesthetics and Steroids for Chronic Peripheral Post-traumatic Neuropathic Pain
The purpose of this study is to evaluate three different injectable solutions used to block ankle nerves to manage ankle pain. The current standard of medical care is to inject a combination of local anesthetics and steroids…
- Trial name
- RESPERIST (NCT03009500)
- Testing
- Bupivacaine, Depo-Medrol Injectable Product, Saline (Sodium Chloride) solution
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University Health Network, Toronto
Restless Legs Syndrome, Neuropathic Pain
Spinal Cord Stimulation for Restless Legs Syndrome
The overall goal of this proposed study is to evaluate the underlying mechanisms of neural control of blood flow in the lower extremities in humans with restless leg syndrome (RLS).
- Trial name
- NCT03539081
- Testing
- Dual-energy X-ray absorptiometry Scan, Laboratory Measurements, Blood Flow Measurement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marshall Holland
Failed Back Surgery Syndrome
Management of Pain Associated With Failed Back Surgery Syndrome
Neuropathic pain is a common complication following different types of spine surgery making negative impact on health, along with life style changes and management, many neurologist prescribed either Pregabalin or Gabapentin to…
- Trial name
- NCT05324761
- Testing
- Pregabalin 75mg, Gabapentin 300mg
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Al-Kindy College of Medicine
Postherpetic Neuralgia
Study of NGX-4010 With the Use of Open Label Lidocaine (2.5%)/Prilocaine (2.5%) Cream for the Treatment of Postherpetic Neuralgia (PHN)
This study is an open-label multi-center to evaluate the tolerability of treatment with NGX-4010 use with pre-patch topical application of a topical anesthetic cream. This is an open-label study.
- Trial name
- NCT00916942
- Testing
- capsaicin 8%, Lidocaine (2.5%)/Prilocaine (2.5%) Cream
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- NeurogesX
Calcitonin, Neuropathic Pain
Calcitonin Therapy on Incidence and Severity of Neuropathic Pain After Spinal Cord Injury
This prospective randomized double blinded study will be conducted to evaluate the effect of early pharmacologic intervention with calcitonin on the incidence or the severity of neuropathic pain after spinal cord injury
- Conditions
- Calcitonin, Neuropathic Pain, Spinal Cord Injury
- Trial name
- NCT05805683
- Testing
- Calcitonin
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Tanta University
Neuropathic Pain
Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of REL-1017 (d-Methadone)
This study evaluated the safety, tolerance, and pharmacokinetics (PK) of d-methadone in a limited dose range, in multiple administrations in humans.
- Trial name
- NCT03638869
- Testing
- REL-1017
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Relmada Therapeutics, Inc.
Hallux Valgus and Bunion (Disorder), Morton Neuroma
Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Foot surgery is a painful surgery that is usually scheduled in outpatients. A good management of analgesia is the crucial point.
- Conditions
- Hallux Valgus and Bunion (Disorder), Morton Neuroma, Metatarsal Fracture, Ingrown Nail
- Trial name
- DISTIB (NCT03504462)
- Testing
- Specific block of medial and lateral plantar nerves
- Where
- France
- Volunteers
- 27 people
- Sponsor
- CMC Ambroise Paré
Spinal Cord Injuries, Neuropathic Pain
Capsaicin 8% Patch for Spinal Cord Injury Neuropathic Pain
A prospective case control study to determine the effectiveness and longevity of 8% capsaicin patch(es) in treating neuropathic pain in persons with spinal cord injury.
- Trial name
- Capsaicin (NCT02441660)
- Testing
- Capsaicin 8% Patch, Low Dose Capsaicin 0.025% Well Patch
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Nerve Pain
A Study to Investigate the Analgesic Efficacy of AZD2423 Compared With Placebo After 28 Days Treatment in Patients With Posttraumatic Neuralgia..
A study to investigate the analgesic efficacy of AZD2423 compared with placebo after 28 days treatment in patients with posttraumatic neuralgia.
- Trial name
- NCT01200524
- Testing
- AZD2423
- Where
- 25 sites in Bulgaria, Denmark and 5 more
- Volunteers
- 133 people
- Sponsor
- AstraZeneca
Piriformis Syndrome, Gluteus Maximus Myofascial Pain
Ultrasound-Guided Interfascial Hydrodissection for Gluteal Myofascial Pain in Piriformis Syndrome: A Prospective Study
This randomized, double-blind prospective trial investigates whether ultrasound-guided interfascial hydrodissection using 10% dextrose is more effective than dry needling in treating gluteal myofascial pain coexisting with…
- Trial name
- NCT07326982
- Testing
- Ultrasound-Guided Interfascial Hydrodissection, Ultrasound-Guided Gluteus Maximus Dry Needling
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.