Clinical trials: Neuralgia Peripheral
Neuropathic Pain
Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain
Based on laboratory studies, donepezil will improve pain relief more than placebo in patients with chronic neuropathic pain who are currently taking gabapentin or pregabalin.
- Trial name
- NCT01743976
- Testing
- Donepezil
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Wake Forest University
Cancer
Exercise Rehabilitation in Veteran Cancer Survivors
Exercise rehabilitation has the potential as a non-pharmacological approach to reduce persistent neuropathic pain in Veterans with lung cancer.
- Trial name
- NCT03621813
- Testing
- Exercise Rehabilitation, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Osteoarthritis, Migraine
Migraine and Neuropathic Pain in Osteoarthritis
The goal of this observational study is to estimate the frequency of neuropathic pain and migraines in a group of patients with osteoarthritis of the knees, hips, hands, spine or other joints.
- Conditions
- Osteoarthritis, Migraine, Neuropathic Pain
- Trial name
- MEDUSA (NCT06224959)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Peripheral Nerve Injury, Postherpetic Neuralgia
Study of Possible Changes in QST After Application of Capsaicin on Patients With Peripheral Neuropathic Pain
The treatment of neuropathic pain ist still a challenge. A new promising therapy is the use of capsaicin on skin. The investigators first experiences with capsaicin in patients with peripheral nerve injury showed changes in the…
- Trial name
- NCT01596491
- Testing
- quantitative sensory testing (QST)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Ruhr University of Bochum
Postherpetic Neuralgia
Evaluate the Efficacy and Safety of DWP05195 in Subjects With Post-Herpetic Neuralgia
The purpose of this study is to evaluate efficacy, safety of administered DWP05195 in Postherpetic Neuralgia.
- Trial name
- NCT01557010
- Testing
- DWP05195, Control
- Volunteers
- 140 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Herpes Zoster, Post-herpetic Neuralgia
Reduction of Postherpetic Neuralgia in Herpes Zoster
The addition of gabapentin therapy to standard antiviral treatment with valacyclovir in acute herpes zoster patients will decrease the incidence of post-herpetic neuralgia.
- Trial name
- NCT01250561
- Testing
- Gabapentin, Valacyclovir
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- Center for Clinical Studies, Texas
Neuropathic Pain
Study of MRgFUS Exablate Treatment Following the Neuropathic Pain
The objective of this study is to capture the change in pain intensity, physical/emotional function, and pain impact for patients diagnosed with neuropathic pain who undergo an Exablate treatment.
- Trial name
- NCT04649554
- Testing
- Exablate treatment
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- InSightec
Musculoskeletal Pain, Neuropathic Pain
Association of High PainDETECT Scores With Pain Region and Diagnosis in Patients Attending a Musculoskeletal and Sports Medicine Clinic
This observational study aims to evaluate the relationship between PainDETECT questionnaire scores, pain regions, and clinical diagnoses in patients presenting to a musculoskeletal and sports medicine clinic.
- Trial name
- PD-MSK (NCT07356115)
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Uskudar University
Pain
Efficacity of a Standardized Hypnotic Message During the Application of a Qutenza (Capsaicin) 8% Patch
QUTENZA® is a skin patch with a high concentration of capsaicin (8%) which is the component responsible for spicy peppers. QUTENZA® is indicated for the treatment of peripheral neuropathic pain in non-diabetic adults either alone…
- Trial name
- ENHYZA (NCT02822625)
- Testing
- QUTENZA®, hypnotic message, music therapy
- Where
- France
- Volunteers
- 69 people
- Sponsor
- Institut de Cancérologie de Lorraine
Neuropathic Pain, Fibromyalgia
Deep rTMS (H-coil) for Neuropathic Pain or Fibromyalgia
This study will investigate the efficacy and safety of "deep" rTMS on neuropathic pain or fibromyalgia. It will be randomized and sham controlled and will last 3 months.
- Trial name
- H-FINEP (NCT06250491)
- Testing
- Deep active rTMS with Hesed coil
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Nadine ATTAL
Herpes Zoster, Neuralgia
Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy (HIV-AN) or Postherpetic Neuralgia (PHN)
The purpose of the study is to evaluate the safety and efficacy of NGX-4010 administered at intervals of no less than 12 weeks over 1 year, based on the presence or return of pain, for the treatment of painful HIV-AN and PHN.
- Conditions
- Herpes Zoster, Neuralgia, Pain, HIV Infections
- Trial name
- NCT00233155
- Testing
- Capsaicin Dermal Patch
- Volunteers
- 100 people
- Sponsor
- NeurogesX
Neuralgia, Postherpetic, Diabetic Neuropathy
Neuropathic Pain Syndrome Patient Study (MK-0000-072)
The purpose of this study is to determine the best way to conduct clinical trials in patients with neuropathic pain (nerve pain). This study will see if generic pregabalin has any effect on neuropathic pain.
- Conditions
- Neuralgia, Postherpetic, Diabetic Neuropathy, Painful Small-Fiber Neuropathy, Idiopathic Distal Sensory Polyneuropathy
- Trial name
- NCT00570310
- Testing
- Comparator: pregabalin
- Volunteers
- 104 people
- Sponsor
- Merck Sharp & Dohme LLC
Neuropathic Pain
Can the Perception of a Treatment Influence Pain Processing - an Examination of Psychological and Neurobiological Mechanisms
The study investigates the effect of an open (in full view of the patient) vs hidden treatment (without the patient's knowledge).
- Trial name
- NCT03109860
- Testing
- Open-hidden
- Volunteers
- 19 people
- Sponsor
- University of Aarhus
Sleep Apnea, Spinal Cord Injuries
Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury
This cross-sectional prospective study will assess the potential association of more severe sleep apnea after spinal cord injury with more intense neuropathic pain, more severe spasticity, and more significant cardiovascular…
- Conditions
- Sleep Apnea, Spinal Cord Injuries, Spasticity, Muscle, Neuropathic Pain
- Trial name
- NCT05687097
- Testing
- Home-based sleep screening test or hospital-unattended sleep screening test, Cardiovascular beat-to-beat monitoring, ECG monitoring
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Diabetic Nephropathy Type 2
Vitamin D in Diabetic Neuropathy
Introduction Diabetic peripheral neuropathy (DPN) is among the most common chronic complications of diabetes mellitus and represents a major cause of morbidity, impaired quality of life, sleep disturbance, chronic pain, and…
- Trial name
- NCT07644520
- Testing
- Vitamin D
- Volunteers
- 150 people
- Sponsor
- Tanta University
Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome
Persistent Post-Lumbar Surgery Pain Syndrome (PSPS) Type II is a Common Condition Encountered in Pain Units, With Limited Available Therapeutic Options. Epidural Pulsed Radiofrequency (PRF) Administered Via Catheter Has Demonstrated Greater Efficacy Compared to the Transforaminal Approach. This Rand
This study is for people who continue to have low back pain after spinal surgery, a condition called persistent spinal pain syndrome type II. Current treatments, such as epidural injections, often provide only limited relief.
- Conditions
- Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome, Chronic Low Back Pain, Post-Laminectomy Syndrome
- Trial name
- EPIPUL (NCT07156513)
- Testing
- Epidural Pulsed Radiofrequency, Betamethasone (Epidural Corticosteroid Injection)
- Where
- 4 sites in Spain
- Volunteers
- 131 people
- Sponsor
- Puerta de Hierro University Hospital
Neuropathic Pain
A Study to Assess the Efficacy, Safety and Tolerability of Pregabalin in Patients With Symptoms of Neuropathic Pain
The objective of this study is to evaluate the efficacy, safety and tolerability for pregabalin using a flexible, optimized dose schedule compared to placebo in relieving the symptoms of neuropathic pain.
- Trial name
- NCT00301223
- Testing
- Pregabalin
- Where
- 7 sites in China
- Volunteers
- 309 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuropathy;Peripheral
Transcutaneous Pulsed Radiofrequency in Diabetic Polyneuropathy
Investigators want to investigate the efficacy of transcutaneous pulsed radiofrequency therapy in the treatment of diabetic peripheral neuropathy symptoms.
- Trial name
- NCT05480527
- Testing
- Transcutaneous pulsed radiofrequency current
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Pain, Neuralgia, Postherpetic
A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Patients With Neuropathic Pain (Postherpetic Neuralgia and Post-traumatic Neuralgia)
The purpose of this study is to evaluate the safety and effectiveness of JNJ-42160443 in the treatment of moderate to severe neuropathic pain in patients with a diagnosis of postherpetic neuralgia and post-traumatic neuralgia.
- Conditions
- Pain, Neuralgia, Postherpetic, Neuralgia, Mononeuropathies
- Trial name
- NCT00964990
- Testing
- JNJ-42160443
- Where
- 48 sites in United States, Belgium and 2 more
- Volunteers
- 112 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pain, Intractable
A Study of the Safety and Tolerability of GA in the Treatment of Patients With Refractory Neuropathic Pain
Previous studies have shown that the anterior cingulate cortex is involved in the regulation of pain and its associated negative emotions, that pyramidal neurons are highly excitable in chronic neuropathic pain conditions, and…
- Trial name
- NCT06596681
- Testing
- GA+clozapine
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Beijing Tiantan Hospital
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