Clinical trials: Neuralgia Peripheral
Chronic Non-specific Low Back Pain
Dose-Response Characterization of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain
Dose-response characterization of VER-01 in patients with chronic non-specific low back pain (CLBP) for whom drug treatment is indicated and previous optimized treatments with non-opioid analgesics have not led to sufficient pain…
- Trial name
- RESPONSE (NCT06475001)
- Testing
- VER-01
- Where
- United Kingdom
- Volunteers
- 652 people
- Sponsor
- Vertanical GmbH
Neuropathic Pain
The Effect of Central Sensitization and Neuropathic Pain After Total Knee Arthroplasty
It has been well known that central sensitization (CS) is a risk factor for inferior outcomes following total knee arthroplasty (TKA).
- Trial name
- NCT05581836
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- The Catholic University of Korea
Sciatica, Radiating Pain
The Effect of Early MSAT Treatment on Sciatica Caused by Traffic Accidents.
The investigators would like to conduct a pilot study prior to a practical randomized control study on the effectiveness of initial MSAT treatment on inpatients complaining of radiating pain and abnormal sensation in the lower…
- Conditions
- Sciatica, Radiating Pain, Paresthesia, Dysesthesia
- Trial name
- NCT06179901
- Testing
- Integrative Korean Medicine Treatment, lower limb motion style acupuncture treatment
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Piriformis Syndrome, Low Back Pain
Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome
The purpose of this study is to evaluate the comparative effects of post-isometric relaxation (PIR) and active isolated stretch (AIS) techniques on reducing pain, improving range of motion, and decreasing functional disability in…
- Conditions
- Piriformis Syndrome, Low Back Pain, Hip Joint
- Trial name
- NCT07526012
- Testing
- Post Isometric Relaxation, Active Isolated Stretching
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Neuralgia, Postherpetic
Dose Ranging Trial to Determine the Safety and Efficacy of EMA401 in Patients With PHN
The study is a randomized, double blind, placebo-controlled, parallel-group comparison (two dose levels of EMA401 versus a placebo group), of safety and efficacy in patients with postherpetic neuralgia.
- Trial name
- NCT02426411
- Testing
- EMA401 200 mg, EMA401 600 mg
- Sponsor
- Spinifex Pharmaceuticals Pty Ltd
Intervertebral Disc Displacement, Sciatica
The Effectiveness of Doin (Conduction Exercise) of the Pelvic Joint for HLD With Radiating Leg Pain
A prospective pilot study will be conducted to investigate the effectiveness and safety in herniated lumbar disc (HLD) patients receiving integrative Korean medicine treatment including Doin (conduction exercise) at a Korean…
- Conditions
- Intervertebral Disc Displacement, Sciatica, Sciatic Radiculopathy
- Trial name
- NCT03571503
- Testing
- Doin (conduction exercise), Herbal medicine, Chuna manual therapy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Capsaicin, Ultaviolet B Light Burn
A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin
The aim of this project is to study the role of transient receptor potential (TRP-) channel V1 (TRPV1+) fibers in the development of cutaneous inflammation induced by epidermal Ultraviolet-B damage.
- Conditions
- Capsaicin, Ultaviolet B Light Burn, Neuropathic Pain, Lidocaine
- Trial name
- NCT03587220
- Testing
- Capsaicin Topical, Ultraviolet-B (UVB) irradiation, Histamine 1%
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Renal Pelvis Cancer, Restless Legs Syndrome
Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in the Adverse Events…
- Conditions
- Renal Pelvis Cancer, Restless Legs Syndrome, Epilepsy, Neuropathic Pain
- Trial name
- NCT01138124
- Testing
- Gabapentin prescriptions
- Volunteers
- 54,202 people
- Sponsor
- GlaxoSmithKline
Diabetic Neuropathy, Neuropathic Pain
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Neuralgia, Postherpetic
- Trial name
- PRISE (NCT07712913)
- Testing
- Experimental: Pregabalin XR, Comparator: Dorene Tabs
- Where
- 15 sites in Brazil
- Volunteers
- 348 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Geriatric Pain
Frailty and Chronic Pain Profiles in Patients Aged ≥65 Years
The primary aim of this study is to investigate the relationship between frailty status and pain type, pain localization, and the Geriatric Nutritional Risk Index (GNRI) in individuals aged 65 years and older who present to an…
- Trial name
- F&P (NCT07373860)
- Where
- Turkey (Türkiye)
- Volunteers
- 393 people
- Sponsor
- Ankara City Hospital Bilkent
Neuropathic Pain
BreEStim Pre-trial
The overall goal is to evaluate the effectiveness of different stimulation protocol of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) in managing neuropathic pain after spinal cord injury (SCI).
- Trial name
- NCT07878429
- Testing
- Single-pulse BreEStim Treatment, Multiple-pulse BreEStim Treatment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Pain, Trigeminal Neuralgia
Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective Study
There is a significant debate whether local infiltration techniques may be a method to treat complicated chronic pain syndromes, e.g. refractory headache.
- Conditions
- Chronic Pain, Trigeminal Neuralgia, Cluster Headache, Post-Zoster Neuralgia
- Trial name
- RetroBlock (NCT03066037)
- Testing
- regional-anaesthesiological infiltration
- Where
- Germany
- Volunteers
- 83 people
- Sponsor
- Charite University, Berlin, Germany
Peripheral Neuropathy
Association Between Work-Related Stress and Peripheral Neuropathic Pain in Female Breast Cancer Post CT
This research aims to find the association between work-related stress and peripheral neuropathic pain in female breast cancer survivors post-chemotherapy.
- Trial name
- NCT07055711
- Testing
- Peripheral Neuropathic Pain
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Superior University
Neuralgia, Postherpetic
A Study Assessing Efficacy of Brivaracetam in Subjects With Persistent Pain After Shingles (Post-herpetic Neuralgia)
Study will assess efficacy, safety and tolerability of brivaracetam in post-herpetic neuralgia (PHN). Duration of 7 weeks divided into 3 periods with no up-titration, nor down-titration.
- Trial name
- NCT00160667
- Testing
- Brivaracetam
- Where
- 50 sites in Belgium, Bulgaria and 8 more
- Volunteers
- 152 people
- Sponsor
- UCB Pharma
Complex Regional Pain Syndrome, Chronic Pain
Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a rare and often debilitating chronic pain condition whereby individuals may experience extreme sensitivity, discoloration, and swelling of the affected area -- along with numerous other…
- Conditions
- Complex Regional Pain Syndrome, Chronic Pain, Causalgia, Complex Regional Pain Syndrome Type I
- Trial name
- LDN-CRPS (NCT06306157)
- Testing
- Low dose naltrexone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Hospital for Special Surgery, New York
Post-herpetic Neuralgia
Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN)
This study was designed to characterize dose response, and evaluate safety and efficacy of three different doses of EMA401 compared to placebo in patients with post-herpetic neuralgia (PHN).
- Trial name
- EMPHENE (NCT03094195)
- Testing
- EMA401
- Where
- 58 sites in Australia, Austria and 17 more
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Osteoarthritis Hand, Neuropathic Pain
Capsaicin in Digital Osteoarthritis Versus Control
The objective of this multicentric, randomized controlled double-blind clinical trial is to demonstrate the efficacy of transdermal application of capsaicin in patients with painful digital osteoarthritis with a neuropathic pain…
- Trial name
- CADOR (NCT06444919)
- Testing
- Capsaicin 179 Mg Cutaneous Patch, Capsaicine low dose 0.04 %
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy Volunteers
Local Anaesthetic Effects of Transcutaneous Amitriptyline
The aim of this study is to assess the local anaesthetic effects of amitriptyline applied on the skin of human volunteers, considering the differential effects on mechanic and thermic sensitivity, the local and general tolerance…
- Trial name
- NCT00355277
- Testing
- Amitriptyline
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Postoperative, Neuropathic Pain
Cartography of Allodynic and Hypoasthetic Territories Following TKA
The purpose of this study is to realize a cartography of the allodynic and hypoasthetic territories associated with a neuropathic pain appearing in patients who underwent a Total Knee Arthroplasty (TKA)
- Trial name
- CARTODOL (NCT02828800)
- Testing
- Cartography of allodynic and hypoasthetic territories
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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