Clinical trials: Neuralgia Peripheral
Neuropathic Pain, Radiculopathy
Comparison of Two Modes of Transcutaneous Electrical Nerve Stimulation (TENS) in Chronic Neuropathic Radiculalgia
This study will compare 2 types of Transcutaneous Electrical Nerve Stimulation (TENS) to treat chronic neuropathic pain. TENS involves the application of electrical stimulation to the skin via surface electrodes to stimulate…
- Trial name
- CROSS-TENS (NCT04169477)
- Testing
- CEFAR Primo Pro (TENS device)
- Where
- 4 sites in France
- Volunteers
- 74 people
- Sponsor
- Lille Catholic University
Sciatica
Evaluate the Safety, Tolerability and Pharmacokinetics of BG00010 (Neublastin) Administered to Sciatica Participants
The primary objective of the study is to determine the safety/tolerability profile, systemic PK behavior, and immunogenicity of single IV and SC administrations of BG00010 to sciatica participants.
- Trial name
- NCT00961766
- Testing
- BG00010 (Neublastin)
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- Biogen
Cervico-Brachial Neuralgia
Effects of Kinesiotherapy Exercises With Cervical Mobilization in Cervicobrachial Neuralgia
To evaluate the effects of kinesiotherapy exercises with cervical mobilization in Cervicobrachial Neuralgia.
- Trial name
- NCT06459466
- Testing
- kinesiotherapy exercises with cervical mobilization, cervical Mobilization
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Complex Regional Pain Syndrome I (CRPS I), Nerve Entrapment Syndrome
Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical Study
This clinical study evaluates the effectiveness of surgical treatment in patients with upper-limb complex regional pain syndrome (CRPS) diagnosed according to the Budapest criteria.
- Trial name
- CRPS-SURG (NCT07263256)
- Testing
- Lesion-Specific Surgical Correction, Median Nerve Decompression
- Where
- Czechia
- Volunteers
- 74 people
- Sponsor
- Jitka Fricova
Piriformis Syndrome, Extracorporeal Shock Wave Therapy
Piriformis Syndrome; Extracorporeal Shock Wave Therapy and Dry Needling
This study is being conducted on patients with piriformis syndrome. Patients are divided into two groups by list randomization method: Extracorporeal shock wave therapy (ESWT) group and Dry neddling (DN) group.
- Trial name
- NCT06530862
- Testing
- ESWT+stretching exercises, Dry needling+stretching exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul Training and Research Hospital
Pruritus, Psychogenic Skin Disease
Psychogenic and Neurogenic Components in Patients With Psychogenic or Neuropathic Pruritus
Scientific research on pruritus is in intensive development, with significant advances in understanding its pathophysiology. The causes of pruritus are very huge; they can be classified into different categories; we can find…
- Conditions
- Pruritus, Psychogenic Skin Disease, Neuropathic Pain, Itch
- Trial name
- PRURINEURO (NCT05024851)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Neuropathic Pain, Spinal Cord Injury
The Effects of Transcranial Direct Current Stimulation on Central Pain in Patients With Spinal Cord Injury
The purpose of this study is to evaluate the analgesic effect of transcranial direct current stimulation (tDCS) applied on motor cortex in patients with spinal cord injury who have chronic neuropathic pain.
- Trial name
- NCT01781065
- Testing
- transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Seoul National University Bundang Hospital
Peripheral Neuropathy, Neuropathic Pain
Safety and Efficacy Study of ADL5859 in Participants With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the effectiveness of ADL5859 in relieving the pain associated with diabetic peripheral neuropathy (DPN) compared with placebo and duloxetine (a marketed drug approved for the treatment of…
- Trial name
- NCT00603265
- Testing
- ADL5859, Duloxetine
- Where
- 27 sites in United States
- Volunteers
- 226 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Diabetic Neuropathy, Painful, Diabetic Neuralgia
Study for Safety and Effectiveness of RWJ-333369 (Carsibamate) for the Treatment of Diabetic Peripheral Neuropathy (DPN).
The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily by mouth compared with placebo in the treatment of Diabetic Peripheral Neuropathy (DPN).
- Conditions
- Diabetic Neuropathy, Painful, Diabetic Neuralgia, Diabetic Polyneuropathy, Diabetic Mononeuropathy
- Trial name
- NCT00501202
- Testing
- RWJ-333369 (carisbamate)
- Volunteers
- 132 people
- Sponsor
- SK Life Science, Inc.
Malignant Brain Tumors
Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors
Focused Ultrasound Focused ultrasound is an attractive method for non-invasive thermal ablation of soft tissue tumors. Treatment begins by acquiring a series of MR images of the target organ.
- Trial name
- FUS-Tumor (NCT01698437)
- Testing
- Non-invasive intervention with focused ultrasound (ExAblate 4000)
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- University Children's Hospital, Zurich
Contact Allergy, Neuropathic Pain
Intranasal Neurostimulation for the Treatment of Neurosensory Abnormalities in CL Wearers (INTAC)
To find out if the use of an intranasal tear neurostimulator (ITN), may be useful in decreasing the pain symptoms felt by patients who experience contact lens discomfort.
- Trial name
- INTAC (NCT04240587)
- Testing
- TrueTear™ intranasal neurostimulator (ITN)
- Where
- United States
- Sponsor
- Tufts Medical Center
Cancer, Chronic Pain
Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC
The primary objective of this study is to describe the administration practices of the antalgic Ketamine in French CLCC (Centre de Lutte Contre le Cancer) in terms of indication (neuropathic sequelae pains, morphine additional…
- Conditions
- Cancer, Chronic Pain, Neuropathic Pain, Opioid Use
- Trial name
- KETACANCER (NCT04459234)
- Testing
- Ketamine use in CLCC sites (indication and administration protocol)
- Where
- 12 sites in France
- Volunteers
- 81 people
- Sponsor
- Centre Leon Berard
Neuropathic Pain, Orofacial Pain
Pregabalin and Orofacial Neuropathic Pain
The purpose of this study is to determine whether pregabalin can decrease pain and improve quality of life in patients who have nerve pain on the mouth or the face
- Trial name
- Pregabalin-Dao (NCT00852436)
- Testing
- pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Postherpetic Neuralgia
To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Postherpetic Neuralgia
Investigate the Efficacy and Safety of HSK16149 capsules in Chinese Postherpetic Neuralgia Following 12 Weeks Treatment in Comparison to Placebo
- Trial name
- NCT05140863
- Testing
- HSK16149 20mg BID, HSK16149 40mg BID
- Where
- 2 sites in China
- Volunteers
- 372 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Neuropathic Pain
Neuropathic Pain Database
To establish the infrastructure for a national neuropathic pain database. To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability, and quality of life.
- Trial name
- NePDatabase (NCT00669006)
- Where
- Canada
- Volunteers
- 789 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Neuropathic Pain
Spinal Cord Stimulation for Neuropathic Pain Relief : Efficacy Study Using the Specific NPSI Questionnaire (NPSI)
Several studies have shown the efficacy of spinal cord stimulation in reducing the intensity of neuropathic pain. This efficacy is defined as obtaining relief of at least 50% of the preoperative pain intensity assessed by the…
- Trial name
- NPSI (NCT04470206)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Foch
Pain, Neuropathic
Comparison of Conventional Dose Regimen and New Dose Regimen of Pregabalin
The purpose of this study is to propose a new flexible dose regimen starting from 75mg using the low dose pregabalin 25 mg and 50 mg comparing the side effect and compliance with the conventional flexible dose regimen staring…
- Trial name
- NCT03691038
- Testing
- Pregabalin 75mg bid, Pregabalin 25mg, 50mg
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Kangbuk Samsung Hospital
Diabetic Foot Ulcer (DFU), Diabetic Symmetrical Polyneuropathy
Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound Healing
Diabetic symmetrical polyneuropathy (DSPN) is a common complication of diabetes that affects the nerves, especially in the legs and feet. It can cause pain, numbness, tingling, weakness, and loss of sensation.
- Trial name
- NCT07877948
- Testing
- Alpha-Lipoic Acid, Vitamin B1, Vitamin B6, Vitamin B12, Vitamin E, Vitamin B1, Vitamin B6, Vitamin B12
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- BREGO Life Sciences
Polyneuropathy, Amyloid, Neuropathic Pain
Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP)
An International, multicenter, epidemiological observational study investigating the prevalence of Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR-FAP) in participants with small fiber polyneuropathy of no obvious…
- Conditions
- Polyneuropathy, Amyloid, Neuropathic Pain, Cardiac Failure, Orthostatic Hypotension
- Trial name
- TRAP2-1 (NCT01705626)
- Where
- 11 sites in Austria, Hungary and 4 more
- Volunteers
- 500 people
- Sponsor
- CENTOGENE GmbH Rostock
Diabetes Mellitus
Effect of Self-Foot Massage on Diabetic Individuals
The aim of this study is to evaluate the effect of self-foot massage on peripheral neuropathic pain, peripheral skin temperature and patient comfort in individuals with diabetes.
- Trial name
- NCT04906226
- Testing
- Self-foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Aksaray University
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