Clinical trials: Neuralgia Peripheral
Symptomatic Neuroma, Phantom Limb Pain After Amputation
Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees
This prospective, observational cohort study evaluates the long-term outcomes of Regenerative Peripheral Nerve Interface (RPNI) surgery in patients with major lower extremity amputations suffering from symptomatic neuromas.
- Conditions
- Symptomatic Neuroma, Phantom Limb Pain After Amputation, Residual Limb Pain, Neuropathic Pain
- Trial name
- RPNI-AMPUTEE (NCT07420192)
- Testing
- Regenerative Peripheral Nerve Interface (RPNI) Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Saglik Bilimleri Universitesi
Neuralgia, Osteoarthritis of the Knee
Nerve Burial for Preventing Neuralgia After Total Knee Arthroplasty
This is a randomized study investigating whether identification, ligation, and burial of superficial branches of the saphenous nerve crossing the surgical field during total knee arthroplasty reduces the rate of post-operative…
- Trial name
- NCT02885467
- Testing
- Total knee arthroplasty with Saphenous nerve burial, Standard total knee arthroplasty
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Medstar Health Research Institute
Spinal Deformity
Sagittal Balance Through Ages
The parameters of the sagittal balance of the cervical, thoracic and lumbar spine vary according to the types of spino-pelvic organization (types 1-4 according to Roussouly).
- Trial name
- ESTA (NCT04467775)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Strasbourg, France
Post-operative Intercostal Neuralgia
Minocycline for the Prevention of Post-operative Intercostal Neuralgia
In about half the patients who have an open chest surgery there is persistent severe pain in the chest. The investigators are examining whether minocycline, a commonly used antibiotic, will prevent pain.
- Trial name
- NCT01314482
- Testing
- Minocycline
- Where
- Australia
- Volunteers
- 116 people
- Sponsor
- University of Adelaide
Neuralgia, Spinal Cord Injury
Symptom Based Treatment of Neuropathic Pain
1. Neuropathic pain in spinal cord injured patients 1. Inclusion criteria pain intensity, visual analogue scale > 3 a LANSS (Leeds assessment of neuropathic symptoms and signs) score of 12 and above aged ≥20 2.
- Trial name
- NCT02180880
- Testing
- Pregabalin and Oxcarbazepine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Ju Seok Ryu
Low Back Pain, Osteoarthritis
Long-term Open-Label Safety Study to Evaluate EN3409
The purpose of the long-terms study is to evaluate the safety, tolerability, and analgesic efficacy of EN3409 in subjects with moderate to severe chronic pain requiring continuous around-the-clock opioid analgesia for an extended…
- Conditions
- Low Back Pain, Osteoarthritis, Neuropathic Pain
- Trial name
- NCT01755546
- Testing
- EN3409
- Where
- 57 sites in United States
- Volunteers
- 304 people
- Sponsor
- BioDelivery Sciences International
Back Pain, Neuralgia
Evaluation of Spinal Cord Stimulation Pulse Rate On Clinical Outcomes
Clinical study to estimate the optimal frequency for stimulation of the spinal cord to achieve relief from back pain.
- Trial name
- PROCO (NCT02549183)
- Testing
- Boston Scientific PRECISION Spinal Cord Stimulator System
- Where
- 3 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Neuralgia, Pudendal Nerve
Comparison of Ultrasound-guided Transgluteal and Finger-guided Transvaginal Pudendal Nerve Block Techniques
Pudendal neuralgia (PN) is a painful and disabling condition, which reduces the quality of life as well. Pudendal nerve injections are essential for the diagnosis and the management of PN.
- Conditions
- Neuralgia, Pudendal Nerve, Pudendal Nerve Block
- Trial name
- NCT03973983
- Testing
- Ultrasound-guided transgluteal pudendal nerve injection (TG-PNI), Finger-guided transvaginal pudendal nerve injection (TV-PNI)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Derince Training and Research Hospital
Neuropathic Pain
Analgesic Effects of rTMS in Peripheral Neuropathic Pain
This study aims to evaluate the long term efficacy over 25 weeks of repeated sessions of magnetic transcranial stimulation of the motor cortex or prefrontal cortex on average pain intensity, quality of life, sleep, neuropathic…
- Trial name
- TRANSNEP (NCT02010281)
- Testing
- rTMS of prefrontal or motor cortex
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Neuropathic
Efficacy Study in Lumbosacral Radiculopathy
This study will be a double-blind, placebo-controlled, parallel group study. After enrolment and initial assessments, subjects will receive 35 days of study medication.
- Trial name
- NCT01110057
- Testing
- GS856553
- Where
- 17 sites in Denmark, France and 3 more
- Volunteers
- 142 people
- Sponsor
- GlaxoSmithKline
Acute Lymphoblastic Leukemia, Neuropathy
Therapeutic Interventions For Pain Induced By Vincristine Treatment For Childhood Acute Lymphoblastic Leukemia (ALL)
Neuropathic pain / peripheral neuropathy (NP/PN) is a known painful complication of vincristine (VCR) therapy; evidence supporting the best treatment plan for pediatric patients is limited.
- Conditions
- Acute Lymphoblastic Leukemia, Neuropathy, Neuropathic Pain
- Trial name
- TINALL (NCT01506453)
- Testing
- gabapentin
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- St. Jude Children's Research Hospital
Chronic Pain
OBSERVATIONAL STUDY OF THE MANAGEMENT OF PATIENTS WITH CHRONIC PAIN
The aim of this study is to evaluate the safety of use, benefits and risks of repeated use of ketamine for each patient with chronic pain in different structures of pain management.
- Trial name
- OKAPI (NCT03319238)
- Testing
- ketamine
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain
Effect of Multitarget tDCS for Neuropathic Pain
This study aims to conduct a randomized controlled trial to evaluate the effect of multitarget transcranial direct current stimulation (tDCS) on pain, depression, anxiety, quality of life and sleep, in patients with neuropathic…
- Trial name
- NCT06510725
- Testing
- Multitarget tDCS, Single-target tDCS
- Where
- 3 sites in China
- Volunteers
- 204 people
- Sponsor
- Xuanwu Hospital, Beijing
Cirrhosis, Hepatic Fibrosis
Prevalence of Pain in Hospitalized Cirrhotic Patients
According to the WHO, pain is an "unpleasant sensory and emotional experience, linked to existing or potential tissue damage, or described in terms suggestive of such damage".
- Conditions
- Cirrhosis, Hepatic Fibrosis, Pain, Acute, Pain, Chronic
- Trial name
- LIVERPAIN (NCT06062108)
- Testing
- Pain evaluation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Neuropathic Pain
EPT 100: Geranium Oil for the Relief of Neuropathic Pain
The purpose of this study is to determine if Geranium oil will relieve a variety of neuropathic pain and some pain relief will last more than 48 hours.
- Trial name
- Geranium Oil (NCT01007747)
- Testing
- Geranium oil
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Pennington Biomedical Research Center
Piriformis Syndrome
Graston vs Manual Myofascial Release Technique in Piriformis Syndrome.
The objective of our study is to compare the effects of Graston and manual myofascial release technique on pain, muscle length and functional status in patients with Piriformis syndrome.
- Trial name
- NCT04588779
- Testing
- Graston, Manual myofascial release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Neuropathic Pain
Spinal Magnetic Stimulation in Neuropathic Pain
It involves delivering a train of magnetic pulses, 5 at each time, to the brain. In the present study, we are using the same method to treat severe pain due to nerve conditions.
- Trial name
- NCT00443469
- Testing
- magnetic stimulation, Magnetic Stimulation with tilted coil
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore General Hospital
Neuropathic Pain, Breast Cancer
Biomarkers of Neuropathic Pain in Women Treated for Breast Cancer
Investigators aim to identify the key phenotypes (biological, psychological, genetic) involved in the transition from acute to chronic neuropathic pain (NP) by comparison of the neuropathic pain phenotypes and genomics of…
- Trial name
- NCT02487524
- Testing
- Cold water test, Autonomic nervous system monitoring, QST
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Helsinki University Central Hospital
Neuropathic Pain, Chronic Pain
Remote Participation (Within USA) Trial of Sana Pain Reliever
Randomized controlled trial to assess the effectiveness and patient perception of the benefit of the Sana Pain Reliever in individuals with chronic neuropathic pain.The study is fully remote with four study visits taking place…
- Conditions
- Neuropathic Pain, Chronic Pain, Pain
- Trial name
- NCT04280562
- Testing
- Sana Pain Reliever
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chemotherapy-induced Peripheral Neuropathy
A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)
The investigators propose that using the Diode Laser fiber type Selective Stimulator (DLss) in patients with chemotherapy-induced peripheral neuropathy (CIPN) will allow for the assessment of changes in small-fiber pain…
- Trial name
- NCT03687970
- Testing
- Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
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