Clinical trials: Neuralgia Peripheral
Neuralgia, Complex Regional Pain Syndromes
Novel Treatment Option for Neuropathic Pain
The purpose of this study is to determine whether the EGFR-inhibitor cetuximab is better than placebo for the treatment of neuropathic pain.
- Trial name
- NoTOPain (NCT02490436)
- Testing
- Cetuximab
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Sorlandet Hospital HF
Postherpetic Neuralgia ( PHN )
Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic Neuralgia
This randomized controlled clinical trial will evaluate and compare the efficacy and safety of intradermal injection of exosomes, platelet-rich plasma, and corticosteroid in patients with post-herpetic neuralgia.
- Trial name
- NCT07565844
- Testing
- Exosomes, PRP, Corticosteroids
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Zagazig University
Postherpetic Neuralgia
Study to Evaluate the Safety and Analgesic Activity of ATx08-001 in Subjects With Postherpetic Neuralgia
This is a Phase 2 randomized, double-blind, placebo-controlled, multiple-dose, multicenter, parallel-group study to evaluate the analgesic activity of ATx08-001, a novel selective peroxisome proliferator-activated receptor…
- Trial name
- NCT01318226
- Testing
- ATx08-001
- Where
- 9 sites in United States
- Volunteers
- 61 people
- Sponsor
- Aestus Therapeutics
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Piriformis Syndrome, Gluteal Pain
Diagnostic Accuracy of Clinical Tests and Diagnostic Criteria for Piriformis Syndrome
Piriformis syndrome is a clinical condition characterized by buttock pain and/or sciatic-like symptoms, and its diagnosis remains challenging because there is no universally accepted diagnostic standard.
- Trial name
- NCT07473349
- Testing
- Ultrasound-Guided Piriformis Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoarthritis
The Clinical Effect of Pregabalin on Neuropathic Pain in Central Sensitized Patients After Total Knee Arthroplasty
In this study, patients scheduled to undergo total knee arthroplasty (TKA) will be screened through a survey for patients with central sensitivity and patients with neuropathic pain as preoperative evaluation.
- Trial name
- NCT05254652
- Testing
- Duloxetine 30mg, Pregabalin 150mg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- The Catholic University of Korea
Rheumatoid Arthritis, Neuropathic Pain
Evaluation of the Effect of Neuropathic Pain on Quality of Life in Rheumatoid Arthritis Patients
Rheumatoid arthritis is a chronic inflammatory disease that mainly affects the joint synovium. Rheumatoid arthritis patients define pain as their major symptom and the most important reason for applying to a healthcare…
- Trial name
- NCT04820426
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Pain Management, Quality of Life
Neuroma-Associated Pain Management After Combat-Related Trauma in Ukraine
This multicenter interventional study in Ukraine is designed to compare the effectiveness of cryoablation and radiofrequency ablation in managing neuroma-associated pain following combat-related trauma.
- Conditions
- Pain Management, Quality of Life, Neuroma, Functional Outcome
- Trial name
- NAP-C/R (NCT07416448)
- Testing
- cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Sciatica
The Efficacy of Active Conservative Treatment for Patients With Severe Sciatica. A Randomized Clinical Controlled Trial
This Study si designed as a Prospective clinical controlled randomized trial. Background: Reviews have demonstrated no or little efficacy for passive conservative treatment modalities for patients suffering from sciatica.
- Trial name
- NCT00246948
- Testing
- Active conservative treatment of sciatica
- Where
- Denmark
- Volunteers
- 181 people
- Sponsor
- The Back Research Center, Denmark
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071988
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Acute Sciatica, Lumbar Disc Herniation
Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation
Comparisons of surgical and non-operative treatment of patients with acute sciatica secondary to lumbar intervertebral disc herniation (AS/LDH) have shown no appreciable difference in outcome.
- Trial name
- NCT01552486
- Testing
- Chiropractic Spinal Manipulative Therapy, Usual Care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Vancouver General Hospital
Lumbar Radiculopathy
Effects of Adding Balneotherapy to a Physical Therapy Program in Patients With Chronic Lumbar Radiculopathy
The aim of this study is to investigate the effects of adding balneotherapy to the conventional physical therapy program on neuropathic pain, disability, daily living activities, and sleep quality in patients with chronic lumbar…
- Trial name
- NCT06846970
- Testing
- Experimental, Active Comparator
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Afyonkarahisar Health Sciences University
Migraine, Neuropathic Pain
Feasibility and Effectiveness of a Specific App to Delivery Mindfulness Sessions
A standardized behavioural approach based on mindfulness delivered mainly by a specific APP on android will be developed and applied for patients with chronic pain conditions, as migraine and neuropathic pain.
- Trial name
- BE_BI_MIND_APP (NCT05101837)
- Testing
- Home program
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Neuropathic Pain
Motor Threshold and Motor Cortex Stimulation
Motor cortex stimulation (MCS) is a form of brain stimulation for patients with neuropathic pain not responsive to medication. An electrode is placed on the surface of the brain and connected to a programmable battery in the…
- Trial name
- NCT02255643
- Testing
- Change of PMT setting
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University of British Columbia
Shingles, Herpes Zoster
A Comparative Study of FV-100 vs. Valacyclovir for the Prevention of Post-Herpetic Neuralgia
This is a multicenter, randomized, double-blind, parallel-group, active controlled comparative study of the safety and efficacy of 2 dosing regimens of FV-100 versus valacyclovir administered for 7 days in subjects with…
- Conditions
- Shingles, Herpes Zoster, Postherpetic Neuralgia
- Trial name
- NCT02412917
- Testing
- FV-100, valacyclovir
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- ContraVir Pharmaceuticals, Inc.
Postherpetic Neuralgia
Efficacy and Safety Study of SLC022 in Treating Pain Associated With Post Herpetic Neuralgia
The purpose of this study is to evaluate the efficacy and safety of SLC022 in treating pain associated with post-herpetic neuralgia (PHN) in recently diagnosed patients.
- Trial name
- NCT00813826
- Testing
- SLC022
- Where
- 19 sites in United States
- Volunteers
- 204 people
- Sponsor
- Solace Pharmaceuticals
Herpes Zoster, Neuralgia
NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is determine if an investigational drug, NGX-4010 (high-concentration capsaicin dermal patches) is effective in treating pain associated with post-herpetic neuralgia (PHN).
- Conditions
- Herpes Zoster, Neuralgia, Pain, Peripheral Nervous System Diseases
- Trial name
- NCT00061776
- Testing
- Capsaicin Dermal Patch
- Where
- 28 sites in United States
- Volunteers
- 300 people
- Sponsor
- NeurogesX
Diabetic Peripheral Neuropathic Pain
Effect of NRD135S.E1 in Peripheral Neuropathic Pain in Diabetic Patients
A multicenter, Phase 2a, randomized, double-blind, placebo (vehicle)-controlled, parallel-group, dose-finding study designed to evaluate the efficacy, safety and tolerability of NRD135S.E1 in adult patients with diabetes mellitus…
- Trial name
- NCT02345291
- Testing
- NRD135S.E1
- Where
- 10 sites in Israel
- Volunteers
- 88 people
- Sponsor
- Novaremed Ltd.
Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury
High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury
Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals.
- Conditions
- Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury, Neuropathic Pain, Peripheral Nerve Injuries, Traumatic
- Trial name
- NCT07705490
- Testing
- High-Intensity Peripheral Magnetic Stimulation, Therapeutic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Type 2 Diabetes, Progressive Relaxation Exercise
Investigation of the Effects of Relaxation Exercises on Neuropathic Pain, Fatigue and Sleep Quality
Relaxation exercises are an important factor in improving diabetes management and quality of life. Diet, exercise, medication and insulin therapy are important components of diabetes management.
- Conditions
- Type 2 Diabetes, Progressive Relaxation Exercise, Neuropathic Pain, Fatigue
- Trial name
- NCT06794918
- Testing
- progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ataturk University
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