Clinical trials: Neurocognitive Function of Elderly Patients
Mild Cognitive Impairment
Effects of Tai Chi Chuan With Different Doses on Cognitive Function in Elderly Patients With Mild Cognitive Impairment
To determine the impact of Tai Chi Chuan with different exercise volume on cognitive function in elderly patients with mild cognitive impairment.
- Trial name
- NCT06372535
- Testing
- Tai Chi Chuan （dose 1）, Tai Chi Chuan （dose 2）, Tai Chi Chuan （dose 3）
- Volunteers
- 540 people
- Sponsor
- Lidian Chen
Mild Cognitive Impairment, Delirium
Remote Cognitive Assessment for Surgical Patients
This is a pilot study to evaluate the use of remote cognitive testing to identify patients who may have cognitive vulnerability and may benefit from cognitive care pathways.
- Trial name
- Remote OR (NCT05566275)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Francisco
Mild Cognitive Impairment (MCI)
Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study
This is a companion real-world external validation study of two pre-registered parent randomized controlled trials (RCTs, protocol IDs: FujianUTCM-1 and FujianUTCM-2).
- Trial name
- NCT07608510
- Testing
- 24-form Simplified Tai Chi (Observational Behavioral Exposure)
- Volunteers
- 150 people
- Sponsor
- Lidian Chen
Fall Patients, Delirium
Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit
This project will implement a 2 step protocol for multidisciplinary geriatric assessment in the Emergency Department (ED). Candidate: Dr.
- Conditions
- Fall Patients, Delirium, Quality of Life, Functional Status
- Trial name
- IMAGE (NCT04068311)
- Testing
- Geriatric Screening tools
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Ohio State University
Stellate Ganglion Block
The Effect of Stellate Ganglion Block on Postoperative Sleep Disturbance and Cognitive Function in Elderly Surgical Patients
Postoperative delirium is an acute state of confusion, which is characterized by changes in attention and cognitive functions and fluctuations in consciousness; postoperative cognitive dysfunction is a common central nervous…
- Trial name
- NCT04800653
- Testing
- Stellate ganglion block
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Yangzhou University
Post Operative Delirium
The Effect of Exercise-Induced Irisin on Brain Function and Postoperative Delirium in Older Adults
The goal of this observational study is to learn how exercise-induced irisin protects the brain. It also explores irisin's effect on postoperative delirium (POD) in older adults.
- Trial name
- NCT07424170
- Testing
- Preoperative physical activity level
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Vitreoretinal Surgery, Cognitive Function Abnormal
The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients
The investigators measured changes in cerebral oxygen saturation (rSO2) and MMSE scores after retrobulbar block performed with levobupivacaine and lidocaine in patients undergoing vitreoretinal surgery.A total of 66 patients over…
- Conditions
- Vitreoretinal Surgery, Cognitive Function Abnormal, Intraoperative Monitoring
- Trial name
- NCT03189329
- Testing
- 2% lidocaine hydrochloride, 0.5% levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Cengiz KAYA
Postoperative Cognitive Dysfunction (POCD), Neurocognitive Function
Target-Controlled Infusion and Postoperative Neurocognitive Outcomes in Geriatric Patients
This prospective observational study aims to evaluate the effects of target-controlled infusion (TCI) on postoperative neurocognitive function in geriatric patients undergoing major non-cardiac surgery.
- Conditions
- Postoperative Cognitive Dysfunction (POCD), Neurocognitive Function, Sedation and Analgesia, Geriatric Patients
- Trial name
- TCI-NEURO (NCT07311447)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Namigar Turgut
Postoperative Cognitive Dysfunction
LINC01844 as a Diagnostic Biomarker for POCD in Elderly Patients
Postoperative cognitive dysfunction (POCD) is a common complication after surgery that is associated with more adverse events and death.
- Trial name
- NCT06387836
- Testing
- Isoflurane 0.8 MAC, Desflurane 0.8MAC
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Shanghai Zhongshan Hospital
Neurodegenerative Diseases, Cognition Disorders in Old Age
Probiotics in Mild Alzheimer's Disease
The main objective is to investigate whether administration of probiotics to patients with mild Alzheimer's Disease (AD) reduces neuroinflammation, improves cognitive function and modifies neurophysiological measures, compared to…
- Trial name
- NCT06181513
- Testing
- Probiotic Blend Capsule
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- University of Nicosia
Malnutrition, Falling
Identification of Risk Patients in Emergency Medical Services
Background: Inadequate nutrition has been associated with growing risk of falling and impaired ability in elderly patients. Falling is a significant threat to the health of the elderly.
- Conditions
- Malnutrition, Falling, Cognitive Impairment
- Trial name
- NCT03759314
- Testing
- Observation
- Where
- Finland
- Volunteers
- 500 people
- Sponsor
- Helsinki University Central Hospital
Perioperative Complications
Effects of Total Knee Replacement on Early Postoperative Cognitive Function in Elderly Patients
To investigate the effects of total knee replacement is harmful to Postoperative cognitive dysfunction
- Trial name
- POCD (NCT02387541)
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
Mild Cognitive Impairment
Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI)
The study will investigate whether dietary modification could provide positive effects on brain functions in elderly people with mild cognitive impairment.
- Trial name
- NCT01219244
- Testing
- caloric restriction, omega-3 supplementation, resveratrol supplementation
- Where
- Germany
- Volunteers
- 330 people
- Sponsor
- Charite University, Berlin, Germany
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Diabetes Mellitus, Type 2, Cognitive Impairment
Diabetes and Cognitive Functions in Middle Age
This study will examine the effects of type II diabetes on cognitive functions and mood in middle-aged patients. In addition, the association between cognitive functions and glycemic controls is studied in patients.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Impairment, Hyperglycemia, Hypoglycemia
- Trial name
- DBC (NCT05919927)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Attention Disorder
Analysis of the Impact of a Temporo-spatial Reorientation Tool on the Speed of Improvement of Confusional Syndrome
Confusion syndrome is defined by attentional disorders and disorganization of cognitive functions that are acute and reversible. There are patient-specific predisposing factors and precipitating factors.
- Trial name
- Rob'Gazette (NCT06498297)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Dementia, Alzheimer's Disease and Related Dementias
HomeCare Medication Management for People With Dementia
This study will evaluate whether the HomeCare medication management system can improve medication adherence and related outcomes for adults age 65 and older living with dementia, Alzheimer's disease, or related dementias.
- Trial name
- NCT07872072
- Testing
- HomeCare
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- HiDO Technologies
Postoperative Cognitive Dysfunction
Evaluation of the Effect of Preoperative Intravenous Amantadine Sulfate on the Postoperative Early Cognitive Functions in a Elderly Patient With Laparoscopic Radical Prostatectomy
Evaluation of the effect of preoperative intravenous administration of amantadine sulfate on the prevention of the development of early cognitive dysfunction in elderly patients undergoing laparoscopic radical prostatectomy
- Trial name
- NCT03988010
- Testing
- Amantadine Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- TC Erciyes University
Dementia, Mild Cognitive Impairment
Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients
The study intends to measure the evolution over time of the cognitive capacity of patients undergoing cataract surgery in relation to the opaque lens removal surgery (cataract) in a population considered to be at risk of…
- Conditions
- Dementia, Mild Cognitive Impairment, Cataract Senile, Cataract
- Trial name
- NCT04047485
- Testing
- Visual Acuity, CAM (Confusion Assesment Method), CATQUEST 9-SF
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Cognitive Impairment, Balance Changes
LSVT Big and Dual Task Training in Cognitive Impaired Patients
The goal of this study ifs to determine the comparative effects of Lee Silverman voice treatment Big and dual task training on balance, cognition and functional mobility in older adults with cognitive impairment.
- Conditions
- Cognitive Impairment, Balance Changes, Cognition Disorders in Old Age, Functional Mobility
- Trial name
- NCT06927362
- Testing
- Lee Silverman treatment big, Dual task training
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University