Clinical trials: Neurodevelopmental Disability
DCild Development Disorders, Pervasive, Autistic Disorder
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Children With Autistic Disorder and Other Pervasive Developmental Disorders (PDD)
The purpose of the study is to evaluate the effectiveness of an oral solution of risperidone (an antipsychotic medication) versus placebo in the treatment of behavioral symptoms in children with Pervasive Developmental Disorders…
- Conditions
- DCild Development Disorders, Pervasive, Autistic Disorder, Developmental Disabilities, Asperger Syndrome
- Trial name
- NCT00261508
- Testing
- risperidone
- Volunteers
- 80 people
- Sponsor
- Janssen-Ortho Inc., Canada
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Inguinal Hernia, Developmental Delay Disorders
Feasibility Study for PANDAS
We have been asked to participate in the Pediatric Anesthesia NeuroDevelopmental Assessment Study (PANDAS), which is a study to compare neurocognitive functions in sibling pairs: one of whom had exposure to anesthesia during…
- Trial name
- NCT00754897
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Children's Hospital of Philadelphia
Developmental, Behavioral and Mental Health, Adhd
Using Telehealth to Deliver Mental Health Services in Primary Care Settings for Children in Underserved Areas
In partnership with a multi-site, Los Angeles-area community clinic consortium, North East Valley Health Corporation (NEVHC), the investigators will use telehealth to integrate pediatric developmental, behavioral and mental…
- Conditions
- Developmental, Behavioral and Mental Health, Adhd, Depression, Anxiety
- Trial name
- NCT02396576
- Testing
- Telehealth Intervention
- Where
- 6 sites in United States
- Volunteers
- 359 people
- Sponsor
- University of California, Los Angeles
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Developmental Disability
Dance Training for Developmental Disabilities
the purpose of this current study is to examine the changes in postural stability in adult individuals with developmental disabilities following exposure to a college based integrative dance training course.
- Trial name
- NCT03660423
- Testing
- Integrative Dance
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Autism
Improving Attention Skills of Children With Autism
Toddlers with autism have poor joint attention skills. Joint attention skills include pointing to objects, following another person's gaze, and responding to invitations to join in a social interaction.
- Trial name
- NCT00065910
- Testing
- Caregiver joint attention intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pediatric ALL, Infant Development
PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes.
- Conditions
- Pediatric ALL, Infant Development, Neurodevelopmental Disorders
- Trial name
- NCT04321200
- Testing
- PANDA Gym, Mobile App
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Refractive Errors, Amblyopia
Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines
Pediatric eye patients receive infrared photoscreener screening and skiascopy as a part of routine examination to compare ability to detect amblyopia risk factors.
- Conditions
- Refractive Errors, Amblyopia, Strabismus, Development Delay
- Trial name
- 2WINbus (NCT03668067)
- Testing
- 2WIN photoscreener
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Alaska Blind Child Discovery
Developmental Dyslexia
Rhythmic Reading Training Compared to 'Abilmente' Method
The purpose of the present study is to compare the effectiveness of Rhythmic Reading Training (RRT), a computer-assisted intervention method that combines sublexical reading exercises with rhythm processing, and that of a…
- Trial name
- NCT03199092
- Testing
- RRT+sat, Abilmente
- Where
- 2 sites in Italy
- Volunteers
- 32 people
- Sponsor
- Catholic University of the Sacred Heart
Intellectual Disability
Evaluation of the Effect of Digital-based Games on the Visual and Cognitive Performance of Young Children With Intellectual Disabilities
This randomized controlled trial aims to evaluate the effect of digital intelligence games on visual and cognitive performance in young individuals with intellectual disabilities.
- Trial name
- NCT07476092
- Testing
- MentalUP Digital Intelligence Game
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Koç University
Intellectual Disability, Mild
Effects of a 12-Week Pickleball Training Program on Cognitive and Motor Skills in Adolescents With Mild Intellectual Disability
This study aims to investigate the effects of a 12-week pickleball training program on cognitive and motor outcomes in adolescents with mild intellectual disability.
- Trial name
- PBID-12 (NCT07586722)
- Testing
- Pickleball Training Intervention Group, Standard Special Education Curriculum
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Elif Top
Neurodevelopmental Disorders, Autism
Early Life Anemia and Children's Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies
The overall project aim is to study children's neurodevelopmental outcomes (including diagnoses of autism, ADHD, and intellectual disability) following exposure to maternal anemia during pregnancy or anemia during the first year…
- Conditions
- Neurodevelopmental Disorders, Autism, ADHD, Intellectual Disability
- Trial name
- NCT06199362
- Where
- Sweden
- Volunteers
- 2,400,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism
SynapDx Autism Gene Expression Analysis Study (STORY)
This study will prospectively enroll approximately 880 children, at least 18 months and less than 60 months of age, who have been referred to a pediatric developmental evaluation center.
- Trial name
- STORY (NCT01810341)
- Where
- 20 sites in United States, Canada
- Volunteers
- 880 people
- Sponsor
- SynapDx
Growth, Child Development
Growth and Body Composition in Children
This study is planned to measure and compare body composition indexes and growth between typically developing children and those with disabilities in South Korea for understanding the nutritional and growth status.
- Conditions
- Growth, Child Development, Disability, Developmental
- Trial name
- NCT03653754
- Testing
- Measurement of growth and body composition
- Where
- South Korea
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Developmental Dyslexia
Comparison of Interventions for Developmental Dyslexia
The purpose of the present study is to compare the effectiveness of Rhythmic Reading Training (RRT), a computer-assisted intervention method that combines sublexical reading exercises with rhythm processing, and that of an…
- Trial name
- NCT02791841
- Testing
- Rhythmic Reading Training, Visual Hemispheric-Specific Stimulation + Action Video Games, Action Video Games
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Catholic University of the Sacred Heart
Autism Spectrum Disorder, Intellectual Disabilities
An Evaluation of Care (Education) and Treatment Reviews for People With Learning Disabilities and Autistic People
Aims In this research project, we will determine whether Care (Education) and Treatment Reviews are helpful for people with learning disabilities and autistic people and their families.
- Trial name
- CECiLiA (NCT06918483)
- Volunteers
- 695 people
- Sponsor
- Coventry and Warwickshire Partnership NHS Trust
Prematurity, Extreme Prematurity
Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder
Extreme prematurity is constantly increasing according to the World Health Organization. However, methods to train premature infants at risk of disability is sorely lacking. The goal of this project is to overcome this problem.
- Conditions
- Prematurity, Extreme Prematurity, Infant Development, Brain Damage
- Trial name
- Premalocom2 (NCT06027645)
- Testing
- Crawling stimulation with a mini-skateboard (i.e. the crawliskate)
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Marianne Barbu-Roth
Developmental Delay
Effects of Educational Training on Children With Developmental Delay
Using a single-blind, randomized controlled design to investigate the additional therapeutic effects of individualized educational training on traditional rehabilitation programs for preschool children with developmental delays.
- Trial name
- NCT04988139
- Testing
- individualized educational training
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Taipei Medical University
Predisposition, Genetic, Cancer Childhood
EXOme Rare Cancers in Children (EXOCARE)
Other than high-dose radiation and previous chemotherapy, few strong risk factors have been identified as causes of childhood cancer.
- Conditions
- Predisposition, Genetic, Cancer Childhood, Development Delay
- Trial name
- EXOCARE (NCT03472807)
- Testing
- Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available
- Where
- 27 sites in France, Reunion
- Volunteers
- 169 people
- Sponsor
- University Hospital, Angers
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