Clinical trials: Neurodevelopmental Disability
Reading Disability
Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults
The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and…
- Trial name
- NCT05523505
- Testing
- RLN real non-invasive brain stimulation intervention, RLN and CCN real non-invasive brain stimulation intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Specific Learning Disorder, Gait
Single and Dual Task Gait Parameters in Children With Specific Learning Difficulties
Children with spesific learning disorders have differences in motor and cognitive abilities compared to normal developing children.
- Trial name
- NCT04783987
- Testing
- Walking asessments
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Afyonkarahisar Health Sciences University
Self-Help Devices, Eye-Gaze Technology
Applying Eye-Gaze Assistive Technology for Children and Youth With Complex Needs
The purpose of this research is to investigate the impacts of applying eye-gaze assistive technology (AT) in children and youth with severe disabilities and complex needs in Taiwan, where eye-gaze AT has not been researched for…
- Conditions
- Self-Help Devices, Eye-Gaze Technology, Severe Physical Disabilities, Communication Disorders
- Trial name
- NCT04377893
- Testing
- Eye gaze AT intervention
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Yu-Hsin Hsieh
Epilepsy, Intellectual Disability
Neuropsychiatric Research Databases for People With Intellectual Disabilities and Epilepsy (REFINE)
This study consists of two parts: Part One: De-identified Database The goal of this part is to establish a research database containing de-identified data about People with Intellectual Disabilities (PwID) and epilepsy, collected…
- Conditions
- Epilepsy, Intellectual Disability, Learning Disability
- Trial name
- REFINE (NCT06780501)
- Where
- 3 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- University of Plymouth
Behavior, Child
Teacher Child Interaction Training (TCIT): Randomized Control Trial
This study is being conducted to evaluate the effects of TCIT on child development, child behavior, and teacher use of skills in the classroom.
- Trial name
- NCT04000230
- Testing
- TCIT, Booster
- Where
- 4 sites in United States
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- University of Miami
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Motor Impairments in Children With Autism Spectrum Disorder: a Multimodal Approach
The general goal of the present proposal, Progetto MOSAICO, is the identification of a multimodal panel of neuropsychological, kinematic, neurophysiological, and genetic markers associated with motor abnormalities present in ASD.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Intellectual Disability
- Trial name
- MOSAICO (NCT04769011)
- Testing
- Clinical evaluation, Neuropsychological evaluation, Neurophysiological evaluation
- Where
- Italy
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Development, Infant, Development Delay
The Effect of the Covid 19 Pandemic Process on the Neuromotor Developments of 6-24 Month-old Babies
Development; It covers the areas of physical, mental, emotional and social development. Development in one area affects other areas as well. Infancy is the period in which children grow and develop the fastest.
- Trial name
- NCT05778357
- Testing
- Group1
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Brain Diseases, Memory Disorders
Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation
The goal of this clinical trial is to investigate the impact of low intensity focused ultrasound pulsation (LIFUP) to two different brain regions, the amygdala and entorhinal cortex, in older adults.
- Conditions
- Brain Diseases, Memory Disorders, Learning Disabilities, Cognitive Impairment
- Trial name
- LIFUPMEMEMOT (NCT03717922)
- Testing
- Low Intensity Focused Ultrasound Pulsation to Amygdala, Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Intellectual Disability, Variable
A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities
This randomized clinical trial is an innovative pilot project to determine the acceptance and impact of telehealth visits on youth with intellectual and developmental disabilities (IDD), their caregivers, and dentists.
- Trial name
- NCT06710483
- Testing
- Pre-Dental Telehealth (PDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Autism, Mental Retardation
Pain and Emotional Expression in Children With Autism or Mental Retardation
The purpose of this study is to describe facial, behavioral and physiologic (heart rate) reactivity of children with autism aged 3 to 6 years old, during a painful stimulation (venepuncture).
- Trial name
- NCT01043822
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Montpellier
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Child Development, Developmental Disabilities
Testing the Effectiveness of Telephone-based Early Childhood Developmental Screening
The purpose of this research study is to test the effectiveness of telephone-based early childhood developmental screening and care coordination, compared to usual care in a primary care pediatrics clinic.
- Conditions
- Child Development, Developmental Disabilities, Ambulatory Care, Screening
- Trial name
- NCT02495025
- Testing
- Telephone-based developmental screening and care coordination
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dyslexia
Transcranial Direct Current Stimulation in the Treatment of Dyslexia.
The present study grounds on the absence of evidence-based treatment in individuals with dyslexia. At this topic, the present study will explore the potential effect of transcranial direct current stimulation (tDCS) over…
- Trial name
- NCT04244578
- Testing
- Active tDCS
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Obesity, Blood Pressure
Upstate New York Infant Development Screening Program
The goal of the Upstate KIDS Study is to track the growth, development and long-term health of children given the increasing use of infertility treatment, occurrence of maternal obesity and pregnancy complications, and rising…
- Conditions
- Obesity, Blood Pressure, Motor Delay, Developmental Delay
- Trial name
- Upstate KIDS (NCT03106493)
- Testing
- None (observational)
- Volunteers
- 6,171 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Apgar Score, Motor Coordination or Function; Developmental Disorder
Effect of Tobacco Use on the Health of the Newborn up to 24 Months.
There is scientific evidence suggesting that tobacco use during pregnancy is associated with several adverse effects in newborns, including low birth weight, respiratory complications, severe neonatal morbidity, perinatal death…
- Conditions
- Apgar Score, Motor Coordination or Function; Developmental Disorder, Lactation, Weight Control
- Trial name
- ETUHeNewBorn (NCT07427706)
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Dyslexia
Effectiveness of a Parent-administered Reading Therapy Program During Summer Break for Dyslexic Children
"After summer break, the reading performance of dyslexic children declines more than those of non-dyslexic children. Indeed, during the summer, dyslexic children are less inclined to read and their consultations with speech…
- Trial name
- REEDVAC (NCT04384952)
- Testing
- Parent-administered reading therapy., Dyslexic's Holiday Workbook
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Physical Activity, Health Promotion
Move it, Move ID! Promotion of Physical Activity in Adolescents With Intellectual Disability
The aim of this study is to develop and implement an mHealth intervention focusing on the promotion of physical activity in adolescents with intellectual disability.
- Conditions
- Physical Activity, Health Promotion, Adolescents, Intellectual Disability
- Trial name
- NCT05149443
- Testing
- theory-based mHealth-intervention (app)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Ghent
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