Clinical trials: Neurodevelopmental Disability
Language Impairment, Hearing Loss
Characterization of Auditory Processing Involved in the Encoding of Speech Sounds
The ability to encode the speech signal is determined by ascending and descending auditory processing. Difficulties in processing these speech signals are well described at the behavioral level in a specific language disorder.
- Trial name
- PRODIPRICIDE (NCT02574299)
- Testing
- E-learning, Hearing aids fitting
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Autism, Intellectual Disabilities With Other Behavioral Symptoms
Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation
The goal of this study is to help children with autism and a co-occurring intellectual disability and their families learn practical strategies for managing issues like irritability, aggression, and other challenging behaviors.
- Conditions
- Autism, Intellectual Disabilities With Other Behavioral Symptoms, Intellectual Disability
- Trial name
- RT-ID (NCT07624448)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Central Auditory Processing Disorder, Dyslexia
Development of an Arabic Central Auditory Processing Remediation Program for Dyslexic Children With(C)APD
Rehabilitation of dyslexic children with (cental) auditory processing disorder. The first group will receive the proposed program the arabic version of differential processing training program and the control group will receive…
- Trial name
- NCT04708899
- Testing
- arabic version of differential processing training program, Arabic computer based auditory traing program(CBAT)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Rana ElShafaei
Intellectual Disability, Exercise
Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability
Adults with intellectual disabilities (ID) have significantly lower levels of fitness compared to the general population. The health benefits of enhanced muscular strength in the general population are well established.
- Conditions
- Intellectual Disability, Exercise, Obesity
- Trial name
- NCT04616638
- Testing
- Resistance Training for Empowerment (RT-POWER), A traditional RT intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Autism Spectrum Disorder, Fra(X) Syndrome
Establishing a Diagnostic and Therapeutic Index in Autism Spectrum Disorder (ASD) and Fragile X Syndrome
The purpose of this study is to accumulate and quantitatively analyze data on the microbiome, serotonin signaling and genetics, and inflammatory cytokines from patients with Autism Spectrum Disorder and Fragile X Syndrome.
- Trial name
- NCT04869930
- Testing
- specimen collection
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nova Mentis Life Science Corp
Vision Impairment, Hearing Impairment
Health Intervention for Adolescents With Intellectual Disability
People with intellectual disability die five to twenty years earlier than the general population. They also experience high levels of unrecognised disease and receive inadequate levels of health promotion or screening.
- Conditions
- Vision Impairment, Hearing Impairment, Obesity
- Trial name
- Ask (NCT00519311)
- Testing
- Health Intervention Package
- Where
- Australia
- Volunteers
- 732 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mental Retardation
Accurate Controlled Dental Sedation
The aim of this study is to evaluate benefits of the method of dental sedation using Target controlled infusion (TCI) combined with Bispectral index (BIS) monitoring in patients with Mental Retardation and challenging behavior.
- Trial name
- ACDS (NCT00963898)
- Testing
- Target controlled infusion(TCI), Bispectral index(BIS)
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Okayama University
Autism Spectrum Disorder (ASD), Developmental Disability
Diné Parents Taking Action Trial
The goal of this clinical trial is to learn if a family support program helps Navajo parents and guardians of children with autism spectrum disorder (ASD) or other developmental concerns.
- Trial name
- NCT07176481
- Testing
- Diné Parents Taking Action Program
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Specific Learning Disorder
Effect of Dual-Task Aerobic Exercise on Children With Specific Learning Disorder
The aim of the present study is to investigate the effects of dual-task aerobic exercise training on attention, balance, and quality of life in children with Specific Learning Disorder.
- Trial name
- NCT07054164
- Testing
- dual-task aerobic exercise, aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Autism Spectrum Disorder, Intellectual Disability
Feasibility and Usability of a Virtual Reality System
Intellectual disability (ID) and autism spectrum disorder (ASD) are often co-occurring neurodevelopmental disorders that require composite intervention.
- Trial name
- NCT06291532
- Testing
- Rehabilitation with VRRS, Conventional cognitive training
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Reading Disorder, Developmental
Camp SMART Speech to Print Summer Literacy Camp
This project aims to explore the feasibility and efficacy of a 6-week, intensive summer literacy intervention provided to children in 1st-3rd grades.
- Trial name
- NCT06442098
- Testing
- CAMP SMART Literacy Summer Camp
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- San Diego State University
Learning Disorders
Risk and Resilience Factors in Learning Disabilities Population
The purpose of this study is to report preliminary outcomes of executive function and psychopathology symptoms of a manual-based psychological intervention for adolescents diagnosed with learning disorders- I can succeed (ICS).
- Trial name
- NCT01652651
- Testing
- I Can Succeed ICS
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Language Impairment, Autism
Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language Impairment
This study will pilot a newly developed Syntactic-Semantic Visual Configuration Intervention (SSVCI) designed to help Urdu-speaking children with language impairment improve their ability to understand and produce phrases and…
- Conditions
- Language Impairment, Autism, Hearing Impaired Children, Down Syndrome
- Trial name
- SSVC-PILOT (NCT07786545)
- Testing
- Syntactic-Semantic Visual Configuration Intervention (SSVCI)
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Executive Function, Social Interaction
Study: Effects of a Collaborative Occupational Therapy Interactive Vaulting
Occupational therapy services will be integrated into an interactive vaulting program which is an equine assisted activity. Children with disabilities ages 5-17 will participate.
- Conditions
- Executive Function, Social Interaction, Disability, Developmental
- Trial name
- NCT04481334
- Testing
- Collaborative occupational therapy interactive vaulting group
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- East Carolina University
Autistic Disorders Spectrum
Word Learning in Children With Autism
The project highlights one of the primary areas of research within the KIDDRC- language and communication. The focus is on language and communication in children with autism and minimal verbal skills (less than 20 spoken words).
- Trial name
- NCT03419611
- Testing
- Multi-Modal, Treatment as Usual, High Intensity Multi-Modal
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kansas
Global Developmental Delay
Virtual Reality and Neuropsychiatric Rehabilitation in Patients With Global Developmental Delay.
Global Developmental Delay is a disorder characterized by failure achievement of expected milestones in different areas of psychomotor development before 5 years of age.
- Trial name
- NCT05879952
- Testing
- TAU + BTsN session, TAU
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Severe Intellectual Disability, Intellectual Disability
Analysis of the Physical Fitness Development Trajectory of Children and Adolescents With Severe Intellectual Disabilities in Orphanages: A Three-year Longitudinal Follow-up Study
This observational cohort study was designed to describe how physical fitness changes over time in children and adolescents with severe intellectual disabilities living in orphanages in China.
- Trial name
- SID-FIT (NCT07291115)
- Testing
- Usual institutional care and school-based physical education
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Xili Wen
Psychosis, Intellectual Disability
Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant Psychosis
This clinical trial will prove whether a large number of people with intellectual disability and treatment-resistant psychosis could benefit from the use of clozapine.
- Trial name
- CLOZ-AID (NCT04529226)
- Testing
- Clozapine, haloperidol, pimozide, olanzapine, risperidone, amisulpride
- Where
- 20 sites in Spain
- Volunteers
- 75 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Developmental Dyslexia
Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia
Dyslexia is a common reading disorder. Specialized instructional programs can improve reading ability in children with dyslexia.
- Trial name
- NCT00068835
- Testing
- Lindamood-Bell training for dyslexia
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
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