Clinical trials: Neurodevelopmental Disability
Neurodevelopmental Disorders, Behavior Disorders
Strongest FamiliesTM Neurodevelopmental
Children and adolescents with neurodevelopmental conditions are 3 to 5 times more likely than their peers to have other mental disorders such as anxiety, depression and disruptive behaviour.
- Trial name
- NCT03835689
- Testing
- Strongest Families Intervention (formerly Family Help)
- Where
- Canada
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Down Syndrome, Intellectual Disability
Escalating Doses of Memantine in Down Syndrome (MEDS-123)
Down syndrome (DS) is typically caused by an extra chromosome 21 in the cell nucleus (trisomy 21, or T21). T21 is both the most common cause of genetically defined intellectual disability and the earliest documented cause of…
- Conditions
- Down Syndrome, Intellectual Disability, Alzheimer Dementia (AD)
- Trial name
- NCT07531940
- Testing
- Memantine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University Hospitals Cleveland Medical Center
Dyslexia
VAlidation of an Educational Technological Tool for Dyslexic Adolescents: an Open Controlled Study
Virtual reality (VR) and augmented reality (AR) are gaining importance in the rehabilitation programs for learning disabilities.
- Trial name
- FORDYS (NCT05028647)
- Testing
- Virtual reality training, Augmented reality training
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Global Developmental Delay
Umbilical Cord Blood Therapy for Global Developmental Delay
This open-label study aims to evaluate the safety and efficacy of autologous or allogeneic umbilical cord blood therapy for children with global developmental delay.
- Trial name
- NCT01769716
- Testing
- Umbilical cord blood transplantation
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- MinYoung Kim, M.D.
Mental Retardation, Developmental Disabilities
Healthy Lifestyles for People With Intellectual Disabilities
Relatively few health promotion and disease prevention programs have included or targeted people with disabilities, and even fewer have focused on individuals with intellectual disabilities.
- Conditions
- Mental Retardation, Developmental Disabilities, Intellectual Disabilities
- Trial name
- HLID (NCT00597948)
- Testing
- Healthy Lifestyles Curriculum
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism, Autism Spectrum Disorder
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Autism
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding autism.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Autism, Akinetic
- Trial name
- NCT04100863
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
ADHD, ASD
Computerized Eye-tracking Attention Training for Children With Special Needs
Children with special needs (e.g. autistic spectrum disorder, attention deficit hyperactivity disorder) are found to have sustained attention problems.
- Conditions
- ADHD, ASD, Learning Disorders
- Trial name
- NCT04178421
- Testing
- Computerized training program
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- Chinese University of Hong Kong
Development Delay, Behavior Problem
The Pro-Parenting Study: Helping Parents Reduce Behavior Problems in Preschool Children With Developmental Delay
The Pro-Parenting Study seeks to determine the added benefit of targeting both parenting stress and parent management strategies to more effectively reduce behavior problems among children with developmental delay (DD).
- Trial name
- NCT03599648
- Testing
- BPT-M, BPT-E
- Where
- 2 sites in United States
- Volunteers
- 959 people
- Sponsor
- University of Oregon
Epilepsy, Mental Retardation
Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy
This is an open randomized controlled study in children with mental retardation and refractory epilepsy in which treatment with ketogenic diet (KD) is compared with treatment with the antiepileptic drug (AED), not tried by the…
- Trial name
- NCT00552526
- Testing
- Ketogenic diet, Antiepileptic drug (AED)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Intellectual Disabilities (F70-F79), Quality of Life
Parenting Training Effect on Quality of Life and Parenting in Parents Who Have Children With Intellectual Disabilities
We conducted a non-randomized control trial. One hundred and forty-one participants in eleven special schools were included in an intervention group (N=71) to participate in parenteral training once a week for five weeks, and in…
- Conditions
- Intellectual Disabilities (F70-F79), Quality of Life, Parenting Intervention
- Trial name
- NCT07205406
- Testing
- group based-parenting training
- Where
- Indonesia
- Volunteers
- 141 people
- Sponsor
- STIKes Satria Bhakti Nganjuk
Global Developmental Delay
Umbilical Cord Blood Therapy for Children With Global Developmental Delay
This open-label study aims to evaluate the safety and efficacy of umbilical cord blood therapy for children with global developmental delay.
- Trial name
- NCT01601158
- Testing
- Umbilical Cord Blood administration, Active Rehabilitation
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- MinYoung Kim, M.D.
Developmental Language Disorder, Speech Sound Disorder
A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04558541
- Testing
- Sensitivity to phonological rules, Sensitivity to semantic category cues.
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Disability Physical, Disabilities Multiple
Attitudes Towards Disability of Nursing and Physiotherapy Students
The general objective of this study is to know the attitude towards people with disability of Nursing and Physiotherapy students in the University of Cadiz. This is a descriptive, correlational, transversal and synchronous study.
- Conditions
- Disability Physical, Disabilities Multiple, Disability Hearing, Disability, Vision
- Trial name
- NCT04498637
- Testing
- 'Attitudes towards people with disability Scale'
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Cerebral Palsy, Muscular Dystrophies
Turkish Version of The Measure of Processes of Care (MPOC)
Family-centred care (FCS) is considered the best practice in providing rehabilitation to children with disabilities and special needs.
- Conditions
- Cerebral Palsy, Muscular Dystrophies, Autism Spectrum Disorder, Traumatic Brain Injury
- Trial name
- NCT03508583
- Testing
- Participation
- Volunteers
- 300 people
- Sponsor
- Hacettepe University
Congenital Disorders of Glycosylation
Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation
Background: Proteins, fats, and other molecules are the body s building blocks. Many of these molecules must have sugars, or chains of sugars, attached to work properly.
- Trial name
- NCT02089789
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Disability, Adolescent Learning, Psychosocial Problem
Effects of a Laughter Yoga Program in Adolescents With Disabilities
A pilot randomized controlled trial will be adopted. A total of forty adolescents with intellectual and physical disabilities will be randomly allocated into either intervention group receiving a 4-week laughter yoga programme (8…
- Trial name
- NCT05832346
- Testing
- Laughter yoga programme
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Chinese University of Hong Kong
Attention Deficit Hyperactivity Disorder
Methylphenidate Study in Young Children With Developmental Disorders
The purpose of this study is to determine if methylphenidate (a common brand name is Ritalin), a medicine used for treating older children with Attention Deficit and Hyperactivity Disorder (ADHD), is also safe and helpful for…
- Trial name
- NCT00517504
- Testing
- Methylphenidate
- Volunteers
- 48 people
- Sponsor
- University of Arizona
Down Syndrome, Autism Spectrum Disorder
Neuro-Nutrition to Support Physiological Function and Cognitive Skills in People With Down Syndrome, Autism Spectrum Disorder, and ADHD
This study aimed to evaluate the impact of a specialized nutritional intervention on physiological performance, sleep quality, and cognitive abilities in individuals with neurodevelopmental disorders, specifically Down syndrome…
- Conditions
- Down Syndrome, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder (ADHD)
- Trial name
- NEURODIET-DSAA (NCT07165509)
- Testing
- T-2 Nutritional Supplement, Structured Dietary Program
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Elizabeth Guadalupe Ibarra Coronado
Children, Disability Physical
Stakeholder Perspectives on the Need for a Digital Solution in Pediatric Rehabilitation
Introduction: Children with chronic conditions receive fragmented rehabilitative care due to the multitude of providers and structures involved, and the constant changes throughout their care and life course.
- Conditions
- Children, Disability Physical, Disabilities Multiple, Disability, Developmental
- Trial name
- ProChRehab (NCT06570148)
- Testing
- semi-directed interview or focus group
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Intellectual Disability
Music-visual Guided Physical Activity Promotion for Adults With Intellectual Disabilities
Objective: Although physical activity (PA) is cardiometabolic and psychologically beneficial to adults with intellectual disability (ID), its initiation and maintenance remain problematic.
- Trial name
- NCT04938999
- Testing
- Music-visual guided physical activity (MVgPA), Usual care
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Chinese University of Hong Kong
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