Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Autism Spectrum Disorder (ASD, Prospective Study
Prospective Clinical Study on Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Childhood Autism
This clinical study aims to evaluate whether a nasal spray containing exosomes derived from human umbilical cord mesenchymal stem cells (hUC-MSC-EXOs) can safely and effectively improve core symptoms in children aged 3-7 years…
- Trial name
- EXO-ASD (NCT07243561)
- Testing
- hUC-MSC-Exos Nasal Spray
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Dongfang People's Hospital
Prosocial Behavior, Anxiety Disorders and Symptoms
Promoting Social-emotional Development and Self-esteem in Primary School Students
This is an effectiveness study into a program ("HiRO") for improving social-emotional development, self esteem and the perceived classroom peer context in primary school students (aged 4-13 years).
- Conditions
- Prosocial Behavior, Anxiety Disorders and Symptoms, Attention Deficit Hyperactivity Disorder, Healthy
- Trial name
- NCT06019429
- Testing
- HiRO, HiRO +judo, School as usual
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Stroke, Dysphagia
Auricular Vagus Nerve Stimulation and Post-Stroke Dysphagia in Older Adults
This study investigates the effect of non-invasive transcutaneous auricular vagus nerve stimulation (tVNS-E) on swallowing rehabilitation in patients over 70 years old after stroke.
- Trial name
- SVA-DPA (NCT07428590)
- Testing
- tVNS-E active device, tVNS-E inactive device
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Autism Spectrum Disorder, ASD
Cord Blood Infusion for Children With Autism Spectrum Disorder
This is a single site, prospective, randomized, double-blind study of a single intravenous autologous or allogeneic, unrelated cord blood (CB) infusion in children ages 2-7 years with Autism Spectrum Disorder (ASD).
- Conditions
- Autism Spectrum Disorder, ASD, Autism, PDD
- Trial name
- Duke ACT (NCT02847182)
- Testing
- Cord Blood Infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Joanne Kurtzberg, MD
Attention-Deficit/Hyperactivity Disorder, Tourette Syndrome
Computerized Working Memory Training in Children With ADHD and Comorbid Tourette Syndrome
The investigators will conduct a randomized placebo-controlled trial of a computerized intervention targeting working memory in 30 children with comorbid Attention-Deficit/Hyperactivity Disorder (ADHD) and Tourette Syndrome (TS).
- Trial name
- NCT02732496
- Testing
- Targeted Cognitive Training (TCT), Youth Appropriate Online Games
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Disorder With Hyperactivity (ADHD), Sustained Attention
The Effects of Lemon Essential Oil Inhalation on Attention in Children With Attention Deficit Hyperactivity Disorder (ADHD)
This randomized, placebo-controlled clinical trial aims to evaluate the acute effects of lemon essential oil inhalation on sustained attention and visual memory in children diagnosed with Attention-Deficit/Hyperactivity Disorder…
- Conditions
- Attention Deficit Disorder With Hyperactivity (ADHD), Sustained Attention, Aromatherapy, Essential Oil
- Trial name
- NCT07586761
- Testing
- Lemon Essential Oil Inhalation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Autism Spectrum Disorder
The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study
This is a multicenter longitudinal study that aims to validate a set of measures that were previously identified as promising candidate biomarkers and/or sensitive and reliable objective measures of social function in ASD for…
- Trial name
- ABC-CT CS (NCT05294705)
- Where
- 5 sites in United States
- Volunteers
- 565 people
- Sponsor
- Yale University
Attention Deficit Disorder With Hyperactivity, Dental Caries
Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
To evaluate the dental status of children using ritalin and suffering from ADHA in comparison to healthy children.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Dental Caries, Dental Occlusion, Traumatic
- Trial name
- NCT00328224
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Bronchopulmonary Dysplasia
Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia
The purpose of this study is to determine if late doses of Infasurf surfactant given when patients are receiving inhaled nitric oxide will interact to improve surfactant function and increase survival without BPD in treated…
- Trial name
- TOLSURF (NCT01022580)
- Testing
- Infasurf surfactant (ONY, Inc.)
- Where
- 21 sites in United States
- Volunteers
- 511 people
- Sponsor
- Roberta Ballard
Hearing Loss, Mental Retardation
Postnatal HCMV Infection in Very Preterm Infants. Implications, Morbidity, Growth and Neurodevelopmental Outcomes.
The aim of this study is to investigate short and long term consequences from early postnatal HCMV infection transmitted via human milk in very preterm infants (birth weight < 1500 g or gestational age < 32 weeks).
- Conditions
- Hearing Loss, Mental Retardation, Microcephaly, Chorioretinitis
- Trial name
- NCT01151462
- Where
- Norway
- Sponsor
- Oslo University Hospital
Autism Spectrum Disorder
Robot-Mediated Intervention for Children With Autism Spectrum Disorders
This study is being done to examine the impact of an interactive, social robotics program in helping children with autism spectrum disorders (ASD) understand emotions and how to better recognize emotions while interacting with…
- Trial name
- NCT02617342
- Testing
- Robot-mediated Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
ADHD, Attention Deficit Hyperactivity Disorder
Healthy Lifestyle in Adults With Attention Deficit Hyperactivity Disorder
The purpose of this study is to understand the relationship between ADHD and the overall health of someone with ADHD. People who have ADHD have trouble paying attention, concentrating, organizing, and planning.
- Trial name
- NCT00879320
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Self-Injurious Behavior, Autism Spectrum Disorder
Using Apollo Neuro in Autistic Children With Self-Injurious Behavior
This study will evaluate the feasibility and acceptability of the Apollo Neuro, a wearable vibrotactile sensory device, in autistic children who engage in self-injurious behavior (SIB).
- Trial name
- NCT07648420
- Testing
- Apollo Neuro device
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Autism Spectrum Disorder (ASD, Sleep Disturbances in Children
Telehealth Exercise Boosts Sleep and Reduces Parental Stress in Autism
This study aims to test whether a physical activity program delivered through telehealth can help improve sleep quality in children with autism spectrum disorder (ASD) and reduce stress and improve well-being in their parents.
- Conditions
- Autism Spectrum Disorder (ASD, Sleep Disturbances in Children, Parental Stress
- Trial name
- NCT07066020
- Testing
- Telehealth-delivered Physical Activity Program for Children with ASD, In-Person Supervised Physical Activity Program, General Health Education Materials
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Hunan Normal University
Conduct Disorder, Oppositional Defiant Disorder
Pathways 2 Success
This study involves a 3-arm randomized controlled trial designed to investigate the feasibility and acceptability of three preventive interventions designed to reduce risk for escalations in adolescent conduct problems.
- Trial name
- NCT06831123
- Testing
- L2B, L2B + App, skills for success
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Intellectual Disability
Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability
Background: Around 15% of the global population has some form of disability. Rights to obtain proper health care is an emphasis in the United Nationals Convention on the Right of People with Disability.
- Trial name
- NCT06737627
- Testing
- no intervention
- Where
- 2 sites in Taiwan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
ADHD
Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD
The randomized control trial (RCT) study includes 2 aims; one being to test whether START increases access to treatment for ADHD.
- Trial name
- START (NCT05796427)
- Testing
- SupporT for ADHD and Related Treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Intellectual Disability, Developmental Disability
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings
Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings is a research study aimed at developing, implementing, and evaluating a…
- Conditions
- Intellectual Disability, Developmental Disability, Axis I Diagnosis, Mental Illness
- Trial name
- NCT04726371
- Testing
- Generic Best Practices, Tailored Best Practices
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Modular Approach for Autism Programs in Schools
The number of students aged 6-21 years with an educational classification of autism spectrum disorder (ASD) in the United States grew by about 19 times over a 19-year period-from 29,076 in 1995-6 to 545,198 in 2014-2015 (IDEA…
- Trial name
- MAAPS (NCT04533607)
- Testing
- MAAPS
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- May Institute
Heart Defects, Congenital
Neuroprotective Effects of Remote Ischemic Preconditioning (RIPC) During Infant Cardiac Surgery
The purpose of this study is to look at whether the use of a simple technique before surgery, which involves inflating a blood pressure cuff on the infant's leg, can improve development of language, motor and thinking skills at…
- Trial name
- NCT01835392
- Testing
- Remote Ischemic Preconditioning, Control
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Nemours Children's Clinic
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