Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Autism Spectrum Disorder
ImPACT Intervention for Children With ASD
This randomised-controlled trial will assess the effect of an early intervention on the social-communicative abilities and brain activity of preschoolers with autism spectrum disorder (ASD).
- Trial name
- NCT03323918
- Testing
- ImPACT, TAU
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University Ghent
Autism Spectrum Disorder
Improving ToM in Children With ASD Through VPT Training: Behavioral and fNIRS Study
This study aims to employ a longitudinal tracking research to investigate the effects of a visual perspective taking intervention on the development of theory of mind in children with autism.
- Trial name
- NCT06196060
- Testing
- Visual perspective taking training, Block building training, Thought-bubble training
- Where
- 3 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing Normal University
Problem Behavior
Steps to Effective Problem Solving in Group Homes
Aggressive/challenging behaviors in individuals with intellectual disability are a major public health concern for them, their families, their service programs and staff, and their communities.
- Trial name
- STEPS (NCT02855008)
- Testing
- STEPS, Food for Life
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Enhancing Early Language and Cognitive Development in Toddlers Through a Culturally Adapted Home-based Parent Intervention
Home-Based Language and Cognitive Intervention for Arab Toddlers in Israel
This study evaluates the effectiveness of a culturally adapted, home-based program designed to improve language and cognitive development in Arab toddlers in Israel.
- Trial name
- CAHBI-T (NCT07233525)
- Testing
- Culturally Adapted Parent-Implemented Intervention, Child Health Education Sessions
- Where
- Israel
- Volunteers
- 240 people
- Sponsor
- Hillel Yaffe Medical Center
Autoimmune Diseases, Mental Disorders Diagnosed in Childhood
Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)
Recent research studies of early onset-obsessive compulsive disorder (OCD) and Tourette's syndrome have questioned whether autoimmunity could play a role in the development of these conditions.
- Conditions
- Autoimmune Diseases, Mental Disorders Diagnosed in Childhood, Schizophrenia
- Trial name
- NCT00001768
- Testing
- Intravenous immunoglobulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit Hyperactivity Disorder
Atomoxetine Asian Study in Adult Subjects With Attention-Deficit/Hyperactivity Disorder (ADHD)
The primary objective of this clinical study is to assess overall safety and tolerability as measured by discontinuation rate due to adverse events in doses up to 120 mg/day in relation to global clinical studies in adult…
- Trial name
- NCT00636818
- Testing
- Atomoxetine
- Where
- 11 sites in China, South Korea and 1 more
- Volunteers
- 45 people
- Sponsor
- Eli Lilly and Company
Attention-Deficit Hyperactivity Disorder
Pharmacokinetics of HLD200 in Children and Adolescents With ADHD
This study was designed to assess the pharmacokinetic effects of a single dose of HLD200 (methylphenidate hydrochloride) in children and adolescents with ADHD.
- Trial name
- NCT01907360
- Testing
- HLD200 (methylphenidate hydrochloride)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Ironshore Pharmaceuticals and Development, Inc
Attention Deficit Hyperactivity Disorder
Neuromodulation of Executive Function in the ADHD Brain
This study aims to determine the transient, modulatory effects of transcranial direct current stimulation (tDCS) on executive function and inhibitory control in patients with ADHD compared to healthy controls.
- Trial name
- NCT04175028
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Smith-Lemli-Opitz Syndrome
Simvastatin Therapy in Smith-Lemli-Opitz Syndrome
This study will evaluate the safety and effectiveness of simvastatin in treating children with Smith-Lemli-Opitz syndrome (SLOS).
- Trial name
- NCT00064792
- Testing
- Simvastatin Susp., OraPlus
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Forbes Porter, M.D.
Autism Spectrum Disorder
Exploring the Efficacy and Usability of the My Autism Passport (MAP).
To address developmental service navigation by families of children with autism spectrum disorder (ASD) an innovative paper-based tracking tool called the Pediatric Developmental Passport (Passport) was created by Dr.
- Trial name
- NCT04259671
- Testing
- My Autism Passport (MAP) Application
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Unity Health Toronto
ADHD
Black Seed Oil in ADHD
Attention-Deficit/Hyperactivity Disorder is one of the most prevalent neuropsychiatric disorders affecting children with known persistence into adulthood in about 60% of patients.
- Trial name
- NCT06542887
- Testing
- Atomoxetine, Black Seed Oil Cap/Tab
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Autism, Autism Spectrum Disorder
Acquisition of Daily Living Skills in Autistic Children: Comparison Between QR Code and a Human Operator
Autism spectrum disorder (ASD), is a condition characterized by deficits in social communication and mutual interaction, as well as repetitive and restricted behaviors and interests.
- Trial name
- NCT06418035
- Testing
- Video modeling by scanning Qr code, Modeling traditional method
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
Mindfulness for Parents of Children With Autism Spectrum Disorder Autism Spectrum Disorder
The current study examines the efficacy of Mindfulness-Based Stress Reduction (MBSR) to reduce parenting stress, lessen parental reactivity and negativity, and decrease child externalizing behaviors among families of children…
- Trial name
- ASD (NCT03459625)
- Testing
- Mindfulness-Based Stress Reduction (MSBR), Psychoeducational Support Group (PE)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Loma Linda University
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Autism, Pervasive Developmental Disorder
Recording Facial and Vocal Emotional Productions in Children With Autism as Part of the JEMImE Project
The purpose of the JEMImE project is to create a serious game to help children with Autism and Pervasive Developmental Disorder (PDD) develop facial and vocal emotions in context.
- Trial name
- NCT03177590
- Testing
- Recordings of facial and vocal emotional productions
- Where
- 2 sites in France
- Volunteers
- 35 people
- Sponsor
- Fondation Lenval
Autism Spectrum Disorder, Down Syndrome
Video Based Breathing Exercise Rehabilitation
The aim of the study was to investigate the effect of video game-based lung volume increasing training on respiratory mechanics in children with developmental delays.
- Trial name
- NCT06125990
- Testing
- Experimental: Study Group (SGr)
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Saglik Bilimleri Universitesi
Attention Deficit Hyperactivity Disorder
Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHD
The aim of this study is to examine the mechanisms by which stimulant medications reduce symptoms in patients with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01415440
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
ADHD
Effects of Brain Breaks on Educational Achievement in Laboratory Settings: The Break4Brain Project
Advancement in teaching methods, together with the frenetic change in the lifestyles of the school population, provides a unique opportunity to advance scientific knowledge.
- Trial name
- NCT06303674
- Testing
- Physical activity with engaging cognitively, Physical activity without engaging cognitively
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Child Development, Mother-Infant Interaction
Clinical Interventions to Mitigate Neurodevelopmental Risk
Family Nurture Intervention (FNI) has been shown to facilitate emotional connection and long-term child developmental progress in the NICU population.
- Conditions
- Child Development, Mother-Infant Interaction, Diabetes Mellitus, Gestational
- Trial name
- NCT04233489
- Testing
- Family Nurture Intervention (FNI)
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Columbia University
Autism Spectrum Disorder, Executive Dysfunction
Non-invasive Brain Stimulation in Children With Autism
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who…
- Conditions
- Autism Spectrum Disorder, Executive Dysfunction, Child Autism
- Trial name
- NCT05105126
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
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