Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder, Gastro-Intestinal Disorder
Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
The investigators propose to investigate Microbiota Transfer Therapy (MTT) for treating patients with Autism-spectrum disorder with Gastrointestinal disorders (constipation, diarrhea, and/or abdominal pain).
- Conditions
- Autism Spectrum Disorder, Gastro-Intestinal Disorder, Constipation, Diarrhea
- Trial name
- NCT06503978
- Testing
- MTP-101P, Vancomycin, Miralax
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Gut-Brain-Axis Therapeutics Inc.
Hepatic Encephalopathy, Minimal Brain Dysfunction
Minimal Hepatic Encephalopathy in Hereditary Hemorrhagic Telangiectasian
HHT or Rendu-Osler-Weber disease is a genetic disease with an autosomal dominant inheritance pattern, characterized by widespread telangiectases that can involve several organs including the intestinal tract and the liver.
- Trial name
- mHE-HHT (NCT03586115)
- Testing
- Critical flicker frequency assessment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Bari
ADHD - Combined Type, ADHD Predominantly Inattentive Type
NeuroTrainer Cognitive Training For Academic Focus
This clinical trial aims to evaluate the feasibility and efficacy of NeuroTrainer cognitive training in improving attentional and executive control functions in students with and without attention-related difficulties.
- Conditions
- ADHD - Combined Type, ADHD Predominantly Inattentive Type, ADHD, Predominantly Hyperactive - Impulsive
- Trial name
- NCT06512974
- Testing
- NeuroTrainer
- Where
- 3 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- NeuroTrainer
Global Developmental Delay
Virtual Reality and Neuropsychiatric Rehabilitation in Patients With Global Developmental Delay.
Global Developmental Delay is a disorder characterized by failure achievement of expected milestones in different areas of psychomotor development before 5 years of age.
- Trial name
- NCT05879952
- Testing
- TAU + BTsN session, TAU
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Mental Health Issue
Improving Psychological Wellbeing by Stress Reduction Among Parents Having Children With Neurodevelopmental Disorders
This project addresses the mental health challenges faced by parents caring for children with Neurodevelopmental Disorders (NDDs) in Bangladesh.
- Trial name
- NCT06166550
- Testing
- Parent's Emotional Intelligence Network, Mobile App, Diary
- Where
- Bangladesh
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Autism Spectrum Disorder, Parental Stress
Mindfulness-Based Intervention for Parents of Autistic Children in Pakistan
This randomized controlled trial evaluated a culturally adapted mindfulness-based intervention for Pakistani parents of children with autism spectrum disorder.
- Trial name
- NCT07863752
- Testing
- Stronger Together Mindfulness-Based Intervention, Psychoeducation Program
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Northeast Normal University
Attention Deficit Hyperactivity Disorder
OROS Methylphenidate (Concerta) in the Treatment of Adult ADHD
This study will look at the effectiveness of osmotic release oral system (OROS) methylphenidate (Concerta) in treating attention deficit hyperactvity disorder (ADHD) in adults.
- Trial name
- NCT02215538
- Testing
- OROS methylphenidate
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Attention Deficit Disorder With Hyperactivity
Effectiveness and Security Testing of a Mobile App
To assess the effectiveness and security of a mobile App (beta version) for self-managing emotion dysregulation in a pragmatic randomized controlled trial with 80 adolescents with attention-deficit/hyperactivity disorder…
- Trial name
- NCT04519008
- Testing
- Mobile app, Treatment as usual
- Volunteers
- 80 people
- Sponsor
- Consorci Sanitari del Maresme
Attention Deficit Hyperactivity Disorder (ADHD)
Trigeminal Nerve Stimulation for ADHD
The purpose of this study is to develop external Trigeminal Nerve Stimulation (eTNS) as a potential nonmedication treatment for attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- TNS for ADHD (NCT02155608)
- Testing
- Active eTNS
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Los Angeles
Autism
Use of Eye Tracking to Aid in Autism Risk Detection
The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series of eye-tracking measures.
- Trial name
- RCFET (NCT06471504)
- Testing
- Eyelink Portable Duo
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Autism
Valproate Response in Aggressive Autistic Adolescents
This study will examine the effect of valproate, a medication used to treat seizures and bipolar disorder, on aggressive behavior in children and adolescents with autism.
- Trial name
- NCT00065884
- Testing
- Valproate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Child Development Disorders, Preterm Infant
Reliability of Hammersmith Examination in Prediction of Neurological Outcomes (REHAPENO)
In this study workers are trying to test the correlation between Hammersmith Infant Neurological Examination and MRI brain/cranial ultrasound with early prediction of neurological developmental outcome of preterm neonates.
- Conditions
- Child Development Disorders, Preterm Infant, Cerebral Palsy
- Trial name
- REHAPENO (NCT03580252)
- Testing
- Correlation analyses for the outcomes
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Abha International Private Hospital
Attention-deficit Hyperactivity Disorder (ADHD)
Phase I Single Dose, Open-Label Pharmacokinetic Study and Single-Blind, Placebo-Controlled Dose Escalation Study of NFC-1 in Adolescents With Attention-Deficit Hyperactivity Disorder
This trial is a Phase 1 study in adolescents with ADHD and genetic disruptions impacting genes in the metabotropic glutamate receptor (mGluR) network.
- Trial name
- NFC1-GREAT (NCT02286817)
- Testing
- NFC-1
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
Intellectual Disability, Mild to Moderate, Adolescence
Real-Time Pose Recognition Technology for Improving Tennis Learning in Individuals With Intellectual Disabilities
This study investigates the effect of real-time pose recognition technology on learning tennis skills in individuals with mild to moderate intellectual disabilities.
- Trial name
- NCT07517016
- Testing
- RPRS Tennis Training, Traditional Face-to-Face Tennis Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Fetal Alcohol Spectrum Disorder
Parenting Training for Children With FASD
Prenatal alcohol exposure can lead to a myriad of adverse developmental outcomes in children, and is the leading cause of mental disability in Canada.
- Trial name
- SF-FASD (NCT02210455)
- Testing
- Strongest Families FASD intervention, Psychoeducation
- Where
- Canada
- Volunteers
- 119 people
- Sponsor
- IWK Health Centre
Tic Disorder, Childhood
Acupuncture Treament in Children With Tic Disorders
This study intends to evaluate the efficacy of acupuncture on tic disorders in Children; and to explore the underlying mechanism of acupuncture intervention on tic disorders based on Magnetic Resonance Diffusion Tensor…
- Trial name
- NCT07588815
- Testing
- Acupuncture, Comprehensive Behavioral Intervention for Tics (CBIT)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Meizhou People's Hospital
Attention Deficit Hyperactivity Disorder Combined
Evaluating the Feasibility of FAM-SOTC Intervention for Families of Adolescents With ADHD: Pilot Study
Attention-deficit/hyperactivity disorder (ADHD), is a highly genetic and complex neurological disorder, where disruptive behavior, emotional imbalance, and lack of attention can interrupt with normal development of adolescents…
- Trial name
- NCT04378517
- Testing
- psychosocial education in parents groups, psychosocial parents support, interviews with APN
- Where
- Iceland
- Volunteers
- 23 people
- Sponsor
- University of Iceland
Attention Deficit Disorder With Hyperactivity, Attention-Deficit-Disordered Children
Evaluation of a Parent/Child Cognitive-Behaviorial Therapy Program in ADHD Children With Emotional Dysregulation Profile
Attention Deficit Disorder (ADD) with or without Hyperactivity/Impulsivity (ADHD) is a neurodevelopmental syndrome that has a lasting impact on the child's daily lifestyle and leads to functional impairment.
- Trial name
- DP-KID (NCT03176108)
- Testing
- Cognitive Behavorial Therapy (CBT), Body mediation
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Montpellier
Aphasia, Anomia
Inner Speech and Naming Treatment for Individuals with Aphasia
Aphasia is a language disorder, commonly resulting from stroke or other brain injury, that impacts a person's ability to communicate.
- Conditions
- Aphasia, Anomia, Language Disorders, Communication Disorders
- Trial name
- NCT05980897
- Testing
- Naming treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- George Washington University
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