Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Developmental Disability, Intellectual Disability
Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities
Children with intellectual/developmental disabilities (ID/DD) will experience less dental anxiety and cooperate better in a Sensory Adapted Dental Environment (modified visual, sensory, and somatosensory stimuli in a regular…
- Conditions
- Developmental Disability, Intellectual Disability, Dental Anxiety
- Trial name
- NCT03218462
- Testing
- Sensory Adapted Dental Environment (SADE)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Virginia Commonwealth University
Intellectual Disability, Developmental Disability
Clinical Trial of Nabilone for Aggression in Adults With Intellectual and Developmental Disabilities
Innovative treatments are urgently needed for severe behavioural problems (SBPs) in adults with intellectual and developmental disabilities (IDD).
- Conditions
- Intellectual Disability, Developmental Disability, Aggression, Behavior Problem
- Trial name
- N-AND (NCT05273320)
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hsiang-Yuan Lin
Attention-Deficit and Hyperactivity Disorder, Anxiety
Correlating Real and Virtual World Behavioral Fluctuations in Adolescence
The present study will explore a new approach to ongoing evaluation and monitoring of fluctuations in personality traits via commercial video games.
- Conditions
- Attention-Deficit and Hyperactivity Disorder, Anxiety, Disruptive Mood Dysregulation Disorder, Depression
- Trial name
- NCT02281825
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Bipolar Disorder, Bipolar I Disorder
Children's Bipolar Network Treatment Trial I
This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN).
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder, Other Specified Bipolar and Related Disorder
- Trial name
- CBN (NCT05427123)
- Testing
- Medication or psychosocial treatment
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Executive Dysfunction, Autism Spectrum Disorder
Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD
This project explores the association between learning and cognitive flexibility by testing whether a cognitive behavioral intervention designed to improve flexibility in ASD changes learning and associated neural activation…
- Conditions
- Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
- Trial name
- NCT05131659
- Testing
- Executive function group therapy
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Children's National Research Institute
Gilles de la Tourette Syndrome
Pallidal Stimulation and Gilles de la Tourette Syndrome
The aim of this study is to evaluate the efficacy and safety of bilateral pallidal stimulation in patients with a severe form of Gilles de la Tourette syndrome.
- Trial name
- STIC (NCT00478842)
- Testing
- Deep brain stimulation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Neurodevelopmental Disorders
KneuroKnits: Participation and Anxiety in People With Neurological Conditions Participating in a Knitting Group
The reported social benefits of knitting combined with the urgent need for social and activity-based programs in the disability community suggest that a knitting intervention may fill a substantial gap in available programs.
- Conditions
- Autism Spectrum Disorder, Neurodevelopmental Disorders, Acquired Brain Injury, Physical Disability
- Trial name
- NCT04639570
- Testing
- KneuroKnits
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Attention Deficit/Hyperactivity Disorder
A Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Disorder.
To evaluate long-term safety exposure
- Trial name
- NCT05279313
- Testing
- Centanafadine Hydrochloride
- Where
- 86 sites in United States, Canada and 1 more
- Volunteers
- 680 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
ADHD
A Peer-Delivered High School Preparatory Intervention for Students With ADHD
This study will test whether a peer-delivered intervention for high school students with ADHD outperforms enhanced school services as usual.
- Trial name
- Summer STRIPES (NCT04571320)
- Testing
- Summer STRIPES, Enhanced School Services as Usual
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Seattle Children's Hospital
Autism Spectrum Disorder
Dietetic Pattern in Children With Autism Spectrum Disorders
To date, it is well documented that the gut microbiota (GM) influences numerous physiological processes in the healthy "host". The alteration of the composition and function of the intestinal microbiota, commonly referred to as…
- Trial name
- NCT04719923
- Testing
- Children with autism spectrum disorders
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Autism Spectrum Disorder
Study of the Visual Perception During Emotional States on Subjects With an Intrusive Disorder of the Development
The Pervasive Developmental Disorders (PDD) are severe neurodevelopmental disorders, affecting nearly 1% of the general population.
- Trial name
- VisioTED (NCT02827279)
- Testing
- emotional induction
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Cognoa ASD Diagnostic Device - Data Collection Study
The primary objective of this study is to collect data to ascertain the PPV and NPV of the current version of the Cognoa diagnostic device.
- Trial name
- NCT03871179
- Testing
- ASD Diagnostic Device
- Where
- United States
- Sponsor
- Cognoa, Inc.
Respiratory Insufficiency of Prematurity
Canadian Oxygen Trial (COT)
Study Question: In infants who are born at gestational ages of 23 0/7 to 27 6/7 weeks, does lowering the concentration of supplemental oxygen to target an arterial oxygen saturation by pulse oximetry (SpO2)of 85-89% compared with…
- Trial name
- COT (NCT00637169)
- Testing
- Titration of oxygen therapy
- Where
- 23 sites in United States, Argentina and 4 more
- Volunteers
- 1,201 people
- Sponsor
- McMaster University
Autism, Autism Spectrum Disorder
Advanced Social Relations Training
Advanced social relations protocol is aimed at young people with autism aged 9-12 years with an intelligence quotient (IQ) ≥ 80.
- Trial name
- NCT06342583
- Testing
- Advanced social relations training with technical device, Advanced social relations training without technical device
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism, Neurodevelopment
Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals
Many people with autism and other developmental conditions have difficulty speaking or do not use speech and need other ways to communicate.
- Trial name
- AAC (NCT07581483)
- Testing
- Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support
- Where
- 2 sites in United States, Kenya
- Volunteers
- 500 people
- Sponsor
- Indiana University
Autism Spectrum Disorder
Effectiveness of Visual-Behavioral Approach and Predictive Factors in Dental Exams for Children With Autism
The objective of the study are: 1. Evaluating the effectiveness of the structural-visual model of behavioral approach on the compliance and cooperativity of children with ASD in dental examinations. 2.
- Trial name
- NCT06470724
- Testing
- Structural visual approach
- Where
- Indonesia
- Volunteers
- 37 people
- Sponsor
- Universitas Muhammadiyah Yogyakarta
Autism Spectrum Disorder, Intellectual Disability
Effectiveness of Music Therapy in Social Skill Intervention for Children With ASD/ID
Autism spectrum disorder (ASD) is a developmental impairment characterized by persistent deficits in social communication and interactions.
- Trial name
- NCT04557488
- Testing
- Music therapy, Behavioral-based social skill training
- Where
- Hong Kong
- Volunteers
- 77 people
- Sponsor
- Education University of Hong Kong
Autism, Autism Spectrum Disorder High-Functioning
PRT for Adolescents With High Functioning Autism
The purpose of this study is to identify improvement in behavioral and social function and changes in the brain following Pivotal Response Treatment (PRT) for Adolescents in highly verbal adolescents with autism spectrum disorder…
- Conditions
- Autism, Autism Spectrum Disorder High-Functioning, Developmental Disability, Child Development
- Trial name
- NCT05987761
- Testing
- PRT for Adolescents
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Stanford University
ADHD
Amiloride Hydrochloride as an Effective Treatment for ADHD
The investigators are proposing to test a medication derived from our prior studies of the gene SLC9A9. This one gene makes NHE proteins that control how we learn and remember items, which is impaired in ADHD and may cause an…
- Trial name
- NCT01733680
- Testing
- amiloride, Behavioral
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- State University of New York - Upstate Medical University
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