Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Autism Spectrum Disorder
Treatment by Therapeutic Body Wraps in Children and Adolescents Suffering From Autism With Severe Injurious Behavior.
Severe injurious behaviors in children with autism spectrum disorder are challenging. First line treatment approaches include behavioral techniques but pharmacotherapy is frequently required despite frequent adverse effects in…
- Trial name
- PACKING (NCT03164746)
- Testing
- Dry sheet Therapeutic body wraps, WET sheet Therapeutic body wraps
- Where
- 13 sites in France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Lille
Attention-deficit/Hyperactivity Disorder
A Genome-wide Association Study on the Endophenotype of Spatial Working Memory in ADHD
Specific Aims: 1. To find the genetic variations associated with spatial working memory performance in patients with ADHD by using genome-wide association studies (GWAS); 2.
- Trial name
- NCT02710929
- Where
- Taiwan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Tourette Syndrome, Motor Tic Disorder
Study of ABX-1431 in Adult Patients With Tourette Syndrome or Chronic Motor Tic Disorder
Two-part study consisting of a double-blind, randomized, placebo-controlled, study at two target dose levels (Part 1) and an open-label, non-randomized study (Part 2) to determine the efficacy of ABX-1431 in treating adult…
- Trial name
- NCT03625453
- Testing
- ABX-1431
- Where
- 8 sites in Germany, Poland and 1 more
- Volunteers
- 50 people
- Sponsor
- Abide Therapeutics
Neurocognitive Impairment, Acute Lymphoblastic Leukemia
Risk of Psychopathology and Neurocognitive Impairment in Leukemia Survivors
1. This study will evaluate the association between changes in basic cognitive and behavioral functioning by the end of chemotherapy treatment, and the later development of higher order executive functions in pediatric acute…
- Trial name
- NCT01014195
- Testing
- Neurocognitive and behavioral evaluation
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- St. Jude Children's Research Hospital
Attention Deficit Disorder With Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
External Trigeminal Nerve Stimulation for Children With ASD + ADHD to Reduce Elevated Symptoms
The goal of this clinical trial is to learn if external trigeminal nerve stimulation (eTNS) works to treat ADHD symptoms in children on the autism spectrum (ASD).
- Trial name
- eTNS CARES (NCT07214545)
- Testing
- Trigeminal Nerve Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Anxiety, Obsessive-Compulsive Disorder
Virtual Reality System for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. The investigators aim to enhance this therapy with the use of virtual reality exposures.
- Trial name
- NCT03636022
- Testing
- VR System, Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Minnesota HealthSolutions
Brain Diseases, Memory Disorders
Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation
The goal of this clinical trial is to investigate the impact of low intensity focused ultrasound pulsation (LIFUP) to two different brain regions, the amygdala and entorhinal cortex, in older adults.
- Conditions
- Brain Diseases, Memory Disorders, Learning Disabilities, Cognitive Impairment
- Trial name
- LIFUPMEMEMOT (NCT03717922)
- Testing
- Low Intensity Focused Ultrasound Pulsation to Amygdala, Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Speech
Thinking in Speech for Children With Autism
This study examines a cognitive therapy for autistic children, Thinking in Speech. Thinking in Speech helps children with autism independently cope with everyday events that cause stress, by developing their ability to use "inner…
- Trial name
- NCT05256095
- Testing
- Thinking in Speech
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
Tic-Disorder
Efficacy of a Habit Reversal Treatment on Tic-symptoms
The main purpose of this study is to evaluate the efficacy of a habit reversal based treatment programme in children and adolescents aged 8 to 18 years with tic disorders.
- Trial name
- NCT02190383
- Testing
- Habit Reversal Training
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Cologne
Tuberous Sclerosis Complex
Studies in Patients With Tuberous Sclerosis Complex
This study is aimed to carry out a systematic study to examine the effects of genetic variants (genetic modifiers) other than TSC genes on phenotypic variability in familial TSC patients (affected parent, child and unaffected…
- Trial name
- NCT03276195
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Translational Genomics Research Institute
Epilepsy, Pregnancy
Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)
Epilepsy is one of the most common neurological disorders affecting women of childbearing age. Poor pregnancy outcomes are increased in these women and their children.
- Trial name
- MONEAD (NCT01730170)
- Where
- 20 sites in United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- Stanford University
Attention Deficit-Hyperactivity Disorder
Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder
The goal of this trial is to investigate the cognitive- and brain-mechanisms underlying decision making (DM) and learning in young adults with Attention-Deficit/Hyperactivity Disorder (ADHD) as well as the modulation of…
- Trial name
- NCT01831622
- Testing
- Ritalin
- Where
- 2 sites in Norway
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Mats Fredriksen
Autism Spectrum Disorder
The Effect of Individualised Homoeopathic Treatment of Autism Spectrum Disorder in Children
The aim of this study is to determine the effect of individualised homoeopathic treatment of children with Autism Spectrum Disorder (ASD).This study is of descriptive case study design, with a structured interview and…
- Trial name
- NCT02363673
- Testing
- Individualised homoeopathic remedy in aqua distilla
- Where
- South Africa
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Cerebral Palsy, Neurological Conditions
Safety and Efficacy Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to Severe) Drooling in Pediatric Patients 3 to 18 Years of Age With Cerebral Palsy or Other Neurologic Conditions
This is an open-label clinical research study of an oral glycopyrrolate liquid for the treatment of chronic moderate to severe drooling in patients with cerebral palsy or other neurological conditions.
- Conditions
- Cerebral Palsy, Neurological Conditions, Mental Retardation, Sialorrhea
- Trial name
- NCT00491894
- Testing
- Oral Glycopyrrolate Liquid
- Where
- 7 sites in United States
- Volunteers
- 137 people
- Sponsor
- Shionogi
Autism, Asperger Syndrome
The Development of Autistic Children Based on Mothers´Response in Autism Behavior Checklist
The purpose of this study is to evaluate the process of development of autistic children, in a direct and indirect intervention context from mother´s response in Autism Behavior Checklist.
- Trial name
- NCT00725556
- Testing
- Speech Therapy
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Federal University of São Paulo
Autism Spectrum Disorder (ASD)
Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children Aged From 2 to Less Than 7 Years Old With Autism Spectrum Disorder.
The purpose of this study was to evaluate the efficacity and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.
- Trial name
- NCT03715153
- Testing
- BUMETANIDE (S95008) for week 0 - 26, Open-Label BUMETANIDE (S95008) for weeks 26 - 52
- Where
- 50 sites in United States, Australia and 10 more
- Volunteers
- 211 people
- Sponsor
- Institut de Recherches Internationales Servier
Autism Spectrum Disorder (ASD)
Neuromotor Task Training in Autistic Children With Motor Difficulties
The goal of this clinical study is to learn whether Neuromotor Task Training (NTT) may help improve functional motor skills in autistic children who have motor difficulties.
- Trial name
- NTT-SCED (NCT07797439)
- Testing
- Neuromotor Task Training
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Groupe Hospitalier Nord-Essonne
Autism Spectrum Disorder
Adapted Judo for Children With Autistic Spectrum Disorders
The project is aligned with one of the overall: To promote social inclusion and equal opportunities, encouraging participation in sport and physical activity.
- Trial name
- AUTJUDO (NCT04523805)
- Testing
- Adapted judo programme
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Autism Spectrum Disorder
Evaluation of Skillflix for Parents of Youth With ASD
The goal of this clinical trial is to evaluate the effectiveness of using a Microskills video training library for training parents of adolescents with ASD in talking with their teens about relationships and sexual health topics.
- Trial name
- NCT05958394
- Testing
- SkillFlix for Parents
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ashley Philliber
Dravet Syndrome
A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
This (DEEp SEA Study) is a double-blind, randomized, placebo-controlled, multicenter study to investigate the efficacy, safety, and tolerability of LP352 in the treatment of seizures in children and adults with DS.
- Trial name
- NCT06660394
- Testing
- LP352
- Where
- 105 sites in United States, Australia and 16 more
- Volunteers
- 108 people
- Sponsor
- Longboard Pharmaceuticals
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