Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Autism Spectrum Disorder
Social Groups for Australian Children on the Autism Spectrum
This study evaluates the KONTAKT social skills group training in Australian children on the autism spectrum compared to an active control group which is a group Art class
- Trial name
- NCT04024111
- Testing
- KONTAKT(c), Art group
- Where
- Australia
- Volunteers
- 84 people
- Sponsor
- Curtin University
Phelan-McDermid Syndrome, Autism Spectrum Disorder
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
The purpose of this study is to comprehensively characterize PMS using standardized medical, cognitive, and behavioral measures and to track the natural history of the syndrome using repeated longitudinal assessments.
- Conditions
- Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
- Trial name
- NCT02461420
- Where
- 5 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pervasive Developmental Disorder
Trial of Low-Dose Naltrexone for Children With Pervasive Developmental Disorder (PDD)
This study will examine the effects of low-dose naltrexone (LDN) on children with autistic spectrum disorders. The investigators hope to show a positive effect on social functioning and language.
- Trial name
- NCT00318162
- Testing
- low dose naltrexone
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Autism Spectrum Disorder
Cerebellar tDCS in Children With Autism Spectrum Disorder
The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorders (ASD) is safe and to…
- Trial name
- NCT04446442
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Autism
Family-Centered Implementation of Parent Training for Autistic Toddlers in Early Intervention
Early Intervention (EI) systems are ill-equipped to serve the many children 12 to 36 months with early signs or a diagnosis of autism spectrum disorder (ASD).
- Trial name
- NCT07471594
- Testing
- Parent Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Tourette Syndrome
Dopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)
Dr. Kevin J. Black at Washington University is conducting a study to learn whether we can use MRI scans to test dopamine function in the brain and to determine whether the brain performs memory tasks differently in Tourette…
- Trial name
- TSfMRI (NCT00634556)
- Testing
- levodopa solution 2mg/ml for i.v. use
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Communication Disorders, Developmental Disabilities
Effects of Intensity of Early Communication Intervention
The purpose of the study is to determine if a more intensive application of communication intervention, i.e. 5 hours per week, will result in more frequent intentional communication acts, greater lexical density, and a better…
- Trial name
- NCT00723151
- Testing
- Milieu Communication Teaching
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Attention Deficit Hyperactivity Disorder, Delayed Sleep Phase Type Circadian Rhythm Sleep Disorder
Blue Wavelength Light-blocking Glasses in ADHD-Insomnia
Patients with ADHD often report staying up late on the computer, watching TV, or using other electronic devices, all strong emitters of blue light which may be contributing to the delayed sleep onset times seen in some of these…
- Trial name
- ADHD (NCT01557595)
- Testing
- Polarized glasses designed to filter out blue light
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Attention Deficit Hyperactivity Disorder
Pharmacokinetics of Two Extended-Release Formulations of Methylphenidate in Children With Attention Deficit Hyperactivity Disorder (ADHD)
This study is designed to provide pharmacokinetic data for the assessment of bioequivalence of Ritalin LA formulation compared to Medikinet ret. concerning plasma levels and efficacy measures.
- Trial name
- MPH-Kinetics (NCT00772161)
- Testing
- Methylphenidate
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Freiburg
Autism Spectrum Disorder, Wandering Behavior
A Pilot Study to Characterize the Household Impact of Locating Devices for Children With ASD Who Wander
This pilot study will obtain preliminary data about the impact of wearable electronic tracking devices (ETDs) as an intervention for children with autism spectrum disorders (ASD) who wander.
- Trial name
- CHILD (NCT03814902)
- Testing
- Electronic Tracking Device
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Northwell Health
Autism Spectrum Disorder, Autism
Project AFECT (Autism Family Empowerment Coaching and Training Program)
The goal of this clinical trial is to learn about the journey of families after their child's diagnosis of autism and to help parents understand autism and get the right treatments for their child.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectrum Disorders, Autistic Disorder
- Trial name
- AFECT (NCT05910502)
- Testing
- Autism Family Empowerment Coaching and Training Program
- Where
- 2 sites in United States
- Volunteers
- 143 people
- Sponsor
- Stanford University
Autism, Autism Spectrum Disorder
Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions
This study is a 12-week randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in youth with Non-Verbal Learning Disorder, High-Functioning Autism Spectrum Disorder, and related…
- Conditions
- Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
- Trial name
- NCT03553875
- Testing
- Memantine Hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Disorder With Hyperactivity
Safety, Tolerability and Efficacy of SPD503 in Treating ADHD in Children Aged 6-17
The purpose of this study is to determine the effects of SPD503 compared to placebo on tasks of sustained attention in children and adolescents aged 6-17 diagnosed with ADHD.
- Trial name
- NCT00150592
- Testing
- SPD503 (Guanfacine HCl)
- Volunteers
- 182 people
- Sponsor
- Shire
Autism Spectrum Disorder
Community-based Adaptive Autism Intervention for Toddlers
The proposed study (CAIT: Community-based Adaptive Autism Intervention for Toddlers) aims to determine the most optimal sequence of interventions for improving the social- communicative, language and cognitive outcomes of…
- Trial name
- CAIT (NCT04283045)
- Testing
- JASPER, JASPER Plus+
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of California, Los Angeles
Anxiety, Autism
Testing a CBT Program for Anxiety in Teenagers With Autism: A Feasibility Study
The objective is to investigate the feasibility of a newly developed manualised group Cognitive Behavioural Therapy (CBT) programme for anxiety in 15 teenagers (aged 13-17 years) with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04838912
- Testing
- Cool Kids (Chilled) Anxiety program adapted to children and youths with autism and anxiety disorders.
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Anxiety, Autism Spectrum Disorder
The Effect of Aroma on Anxiety Among Children With Autism.
This study evaluates the effects of essential oils on anxiety scores among children who have an autism spectrum disorder. One third of the children will receive a control blend of oils, one third of the children will receive a…
- Trial name
- NCT03489811
- Testing
- Test Essential Oil Blend, Active Essential Oil Blend, Control Blend
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Developmental Dyslexia
Telerehabilitation vs. in Presence Rehabilitation of Reading Disorders Using the Rhythmic Reading Training (RRT)
The aim of the study is to compare the effectiveness of telerehabilitation vs. in presence rehabilitation of reading disorders, using a rhythm-based intervention for reading (i.e., Rhythmic Reading Training)
- Trial name
- NCT04995471
- Testing
- In presence RRT - prototype software, In presence RRT - online platform, Tele-RRT - prototype software
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Bipolar Disorder (BD), Organoids
Analysis of Early Neurodevelopmental Alterations in Bipolar Disorder Based on Cortical Organoid Models
Demonstrate the existence of neurodevelopmental alterations in organoids derived from samples of patients with bipolar disorder (BD) with a neurodevelopmental (ND) component, compared with patients with bipolar disorder (BD)…
- Conditions
- Bipolar Disorder (BD), Organoids, Neurodevelopmental Conditions
- Trial name
- BIPODEV (NCT06968598)
- Testing
- blood sample
- Volunteers
- 10 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Autism Spectrum Disorder
Autism, Sport and Society: Conversations With Parents
In order to examine the experience of children with ASC in physical activity at home, at school, and in the local community, parents of children with ASC will be asked a number of open ended interview questions.
- Trial name
- NCT04275063
- Volunteers
- 30 people
- Sponsor
- Midlands Psychology CIC
ADHD, Stimulant-Induced Euphoria
Prevention of Stimulant-Induced Euphoria With an Opioid Receptor Antagonist
The purpose of this study is to a) assess the efficacy of naltrexone in preventing stimulant-induced euphoria in adults with ADHD, b) assess whether naltrexone will interfere with the clinical efficacy of stimulants in treating…
- Trial name
- NCT01673594
- Testing
- SODAS MPH, Naltrexone
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Massachusetts General Hospital
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