Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Autism
Project VOICES: Vocal Optimization in Children Elevating the Spectrum
Thirty percent of children with autism barely talk or do not talk at all despite years of intervention. This study aims to address this important and long-standing challenge by developing a novel intervention to increase the…
- Trial name
- Project VOICES (NCT06875843)
- Testing
- Contingent responses, Contingent responses plus vocal elicitation strategies, Non-contingent control
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center
Attention Deficit Hyperactivity Disorder
Individualized Precise Localization of rTMS on Precentral and Parietal Gyrus
Attention deficit hyperactivity disorder (ADHD) patients have some problem with sustained attention. The dorsal anterior cingulate cortex (dACC) plays a key role for attention control.
- Trial name
- NCT03515408
- Testing
- rTMS
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Autism Spectrum Disorder
Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disorders and Moderate to Severe Intellectual Disability: Feasibility and Safety Study.
The investigation team propose in this study to specifically evaluate the feasibility of using oxytocin in the form of an intranasal spray in a specific population of children with autism spectrum disorder and intellectual…
- Trial name
- OT-DEFI (NCT05864508)
- Testing
- Oxytocin nasal spray
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Autism Spectrum Disorder
Vitamin/Mineral Supplement for Children With Autism
This is an open-label 3 month clinical trial of a vitamin/mineral supplement designed for children with autism.
- Trial name
- NCT04845776
- Testing
- ANRC Essentials Plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Tourette Syndrome
Ecopipam Tablets to Study Tourette's Syndrome in Children and Adolescents
This study evaluates the effect of ecopipam tablets in children and adolescents in the treatment of Tourette's Syndrome (TS). Half of the participants will receive ecopipam tablets, while the other half will receive matching…
- Trial name
- D1AMOND (NCT04007991)
- Testing
- Ecopipam
- Where
- 70 sites in United States, Canada and 3 more
- Volunteers
- 153 people
- Sponsor
- Emalex Biosciences Inc.
Anxiety Disorder
Cipralex® for Anxiety Disorders in Adolescents
The primary objective is to examine whether Cipralex® is effective and safe in the treatment of anxiety disorders in youth. The secondary objective is to identify changes in arousal and stress response from pre- to post-treatment…
- Trial name
- CAP-E (NCT01293838)
- Testing
- Cipralex®
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Ottawa
Communication Disabilities
Eye-tracking Technology for Severe Communication Disability
The aim of this project is to develop an Augmentative and Alternative Communication intervention through the use of Eye tracker system.
- Trial name
- NCT05808478
- Testing
- AAC + Eye Tracking, AAC
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autistic Disorder
A Study of RO5028442 in Adult Male High-Functioning Autistic Patients
This multi-center, randomized, double-blind study will evaluate exploratory biomarkers and the safety and tolerability of a single dose of RO5028442 in adult male high-functioning autistic patients.
- Trial name
- NCT01474278
- Testing
- RO5028442
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Hoffmann-La Roche
Autism, Autism Spectrum Disorder
Social Robotics for Autism
Socio-pragmatics focuses on the study of language in the context of social interactions. It explores how individuals use language to communicate effectively in specific social situations, taking into consideration the social…
- Trial name
- SRI (NCT06974240)
- Testing
- Experimental Group, control group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Hemiplegic Shoulder Pain
Bobath Approach On Hemiplegic Shoulder Pain
In this study, it is investigated that whether Bobath approach is superior to conventional physiotherapy in terms of improving hemiplegic shoulder pain, spasticity and upper extremity functionality in stroke patients.
- Trial name
- BAHSP (NCT04768140)
- Testing
- Bobath treatment approach, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Arel University
Sickle Cell Disease, Cognitive Impairment
Cognitive Rehabilitation in Sickle Cell Disease
The majority of school-age children with sickle cell disease (SCD) experience neurocognitive deficits, even in the absence of stroke.
- Trial name
- NCT01793740
- Testing
- Cogmed
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Duke University
Autism Spectrum Disorder
The Impacts of Theta-burst Stimulation on Children and Adolescents With Autism Spectrum Disorder
The investigator would like to investigate the impact of theta-burst stimulation over posterior superior temporal sulcus in children and adolescents with autism spectrum disorder
- Trial name
- NCT03621189
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Attention Deficit Hyperactivity Disorder
Placebo-Controlled Multi-Centre Double-Blind Trial for Adults With Extended-Release Methylphenidate for ADHD
Investigation of efficacy and tolerability of extended-release MPD in adults with ADHD, compared with a placebo, and to acquire knowledge through long-term observation of adults
- Trial name
- EMMA (NCT00619840)
- Testing
- methylphenidate hydrochloride
- Where
- Germany
- Volunteers
- 363 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Anorexia Nervosa, Obsessive Compulsive Disorder
Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions
The purpose of this study is to better understand the long-term progress of people with obsessive-compulsive disorder (OCD) and related conditions such as anorexia nervosa, Tourette syndrome, and trichotillomania.
- Conditions
- Anorexia Nervosa, Obsessive Compulsive Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT00004550
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Mental Health (NIMH)
ADHD
Testing a New Method to Improve Informed Consent in Prison Research
Understanding of informed consent is often limited in prison, due to unique challenges faced by detained people. This study will test a modified "teach-to-goal" informed consent process compared to standard procedures.
- Trial name
- Spark BATIR (NCT06378281)
- Testing
- Modified teach-to-goal informed consent
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Stéphanie Baggio
Child Behavior Disorders
The Inner Garden and Care for Children With Moderate to Severe Agitation
The objective is to compare the care including the solution of ambient sensory biofeedback "Inner Garden", compared to the care without this solution, on the regulation of behavioral disorders during a crisis requiring to take…
- Trial name
- ESSAIMS (NCT04610281)
- Testing
- Inner Garden
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open Label
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT05494398
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Stanford University
Tourette Disorder, Tic Disorders
Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder
Yigansan was used in Ming dynasty by Xue Kai as a remedy for restlessness and agitation in children. We expect that the total YGTSS scores of Yigansan-treated subjects will be significantly reduced compared to that of…
- Trial name
- NCT03564132
- Testing
- Yigansan
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- China Medical University Hospital
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome (FAS)
Development of Education Materials for Prevention of FAS in Russia
This study is designed to increase knowledge and awareness to prevent Fetal Alcohol Syndrome in Russian children through development of printed FAS education materials targeting women of childbearing age in Russia.
- Conditions
- Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome (FAS), Alcohol Related Neurodevelopmental Disorder, Alcohol Use Complicating Pregnancy, Unspecified Trimester
- Trial name
- NCT01971398
- Testing
- Positive FASD education brochure, Negative FASD education brochure, Active comparator (a general women's health brochure)
- Where
- 3 sites in United States, Russia
- Volunteers
- 422 people
- Sponsor
- University of Oklahoma
Autism Spectrum Disorder
Do Sleep and Circadian Rhythm Disturbances Impact the Cognitive and Behavioural Development of Children With Autism?
The primary objective of this study is to undertake a longitudinal investigation of the impact of sleep and circadian rhythm disturbances on cognitive and behavioural trajectories in children with autism spectrum disorder (ASD)…
- Trial name
- NCT02878499
- Testing
- polysomnography
- Where
- 5 sites in France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Strasbourg, France
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