Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Sensory Disorders, Autism
Exposure Therapy for Auditory Sensitivity in Autism
Auditory hyper-reactivity affects up to 66% of children with autism spectrum disorder (ASD) and has been linked to greater stress and anxiety for children and their families.
- Conditions
- Sensory Disorders, Autism, Autism Spectrum Disorder, Autism With High Cognitive Abilities
- Trial name
- NCT03206996
- Testing
- Exposure therapy, Psycho-education, Caregiver education/home program development
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Florida
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Attention Deficit Hyperactivity Disorder
Genetic Liability in the Brain Morphology of Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD) is a heritable psychiatric disorder with onset in childhood. Twin and adoption studies indicate that additive genetic factors explain up to 80% of the variance underlying…
- Trial name
- NCT00161161
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Autism
Treatment of Children With Autism Spectrum Disorders and Epileptiform EEG With Divalproex Sodium
The purpose of this study is to determine if treatment of epileptiform abnormalities in children with autism spectrum disorder will improve any behaviors in these children.
- Trial name
- NCT02094651
- Testing
- divalproex sodium
- Where
- 2 sites in United States
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder
Structured Function-Based Elopement Treatment Program
This study aims to extend the researchers' prior work on Function-Based Elopement Treatment (FBET) with a randomized controlled trial to evaluate the efficacy of FBET in 76 children with autism spectrum disorder (ASD) and…
- Trial name
- FBET (NCT03899831)
- Testing
- Function-Based Elopement Treatment (FBET), Parent Education Program (PEP)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Emory University
Attention-Deficit/Hyperactivity Disorder (ADHD)
Virtual Reality for Parent Training Intervention
Previous research has shown how parental responses can affect ADHD symptoms by triggering dysfunctional cyclic processes. Therefore, it may be useful within rehabilitative treatments to include parent training (PT).
- Trial name
- NCT05809388
- Testing
- Parent training, Virtual Reality-assisted PT sessions
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autistic Disorders Spectrum, Adhd
Studies of Brain and Body Interaction
The goal of this study is to characterize biophysiolgoical signals as a comprehensive profile of the nervous systems in order to understand interactions between the brain and body, while an individual performs naturalistic…
- Conditions
- Autistic Disorders Spectrum, Adhd, Asperger Syndrome, Alzheimer Disease
- Trial name
- NCT03672266
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers University
High-functioning Autism
Pain in Autism Spectrum Disorder
The proposed project will be first performed on individuals with HF-ASD with their expected heterogeneity and healthy control (HC) subjects in order to explore the pain processing and modulation mechanisms underlying the pain…
- Trial name
- NCT03413241
- Where
- Israel
- Volunteers
- 183 people
- Sponsor
- Rambam Health Care Campus
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Attention Deficit Hyperactivity Disorder (ADHD), Impulsive Aggression
Exploratory fMRI Study on the Treatment for Impulsive Aggression in Children With ADHD
The purpose of this study was to evaluate the effect of 4-week SPN-810 treatment on brain functioning in patients aged 8-12 years with ADHD and associated feature of impulsive aggression (IA).
- Trial name
- NCT03638466
- Testing
- Functional Magnetic Resonance Imaging (fMRI), Magnetic Resonance Spectroscopy (MRS), Point Subtraction Aggression Paradigm (PSAP) Task
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Math Learning Disability
Understanding Cognitive-Academic Bidirectionality in Math Learning Disabilities
The goal of this clinical trial is to test the effects of an innovative intervention designed to improve math skills in first graders at risk for math disabilities.
- Trial name
- NCT07220746
- Testing
- Coordinated Treatment, Math Treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Vanderbilt University
Premature Birth, Extreme Prematurity
The Pilot Experimental Study of the Neuroprotective Effects of Exosomes in Extremely Low Birth Weight Infants
To study the safety and efficacy of intranasal administration of exosomes derived from mesenchymal stromal cells on long-term neurodevelopmental outcome in extremely low birth weight infants born at gestational age 25/0-27/6…
- Conditions
- Premature Birth, Extreme Prematurity, Preterm Intraventricular Hemorrhage, Hypoxia-Ischemia, Cerebral
- Trial name
- NCT05490173
- Testing
- Exosomes derived from mesenchymal stromal cells (MSCs)
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare
ADHD
Double-blind, Placebo-controlled, Randomised Withdrawal, Extension, Safety and Efficacy Study of LDX in Children and Adolescents Aged 6-17
The main aim of this study is to evaluate the long-term maintenance of efficacy of LDX after administered to children and adolescents aged 6-17 with ADHD for at least 6 months
- Trial name
- NCT00784654
- Testing
- Lisdexamfetamine dimesylate (LDX)
- Where
- 51 sites in United States, Belgium and 7 more
- Volunteers
- 276 people
- Sponsor
- Shire
Development Delay
Comparative Effects Of Creative Movement & Play Based Interventions On Motor Skills
Children with developmental delay often face challenges in motor skills, balance, and overall quality of life, requiring interventions that are both effective and engaging.
- Trial name
- NCT07307105
- Testing
- creative movement intervention, play based intervention
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Autism, Asperger Syndrome
The Development of Autistic Children Based on Mothers´Response in Autism Behavior Checklist
The purpose of this study is to evaluate the process of development of autistic children, in a direct and indirect intervention context from mother´s response in Autism Behavior Checklist.
- Trial name
- NCT00725556
- Testing
- Speech Therapy
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Federal University of São Paulo
ADHD
Multimodal Biomarkers Predicting Medication-Induced Adverse Effects in Children With ADHD
To build a multimodal model combining neuropsychological, neurophysiological, and metabolomic measures to identify biomarkers predicting MPH-induced adverse effects and their underlying mechanisms, supporting individualized risk…
- Trial name
- NCT07900451
- Testing
- methylphenidate
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit in Intellectual Disability
Outcomes Measures in Intellectual Disability
Objective quantitative primary endpoints are lacking in Clinical trials in intellectual disability. We propose to develop quantitative interactive attention evaluation criteria in patients with intellectual disability by using…
- Trial name
- EVALDI (NCT03878251)
- Testing
- Quantitative attention evaluation criteria in intellectual disability
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth, Neurodevelopmental Disorders
Swaddling to Improve Neurodevelopment for Preterm Babies
The investigators will test a new medical grade swaddling system for optimal and more appropriate positioning for preterm infants. This is a trial focused on sleep state, state regulation and long-term neurodevelopment.
- Trial name
- NCT04715451
- Testing
- Novel Swaddle
- Sponsor
- Johns Hopkins University
Epilepsy
Neurodevelopmental Effects of Antiseizure Medications (NEAM) - UG3 Phase
To compare in-person to remote video assessments in children to determine the reliability of remote evaluations for future neuropsychological assessments and set a precedent for future investigations.
- Trial name
- NCT05364853
- Testing
- In-Person Testing, Remote Testing
- Sponsor
- Stanford University
Speech Sound Disorder
Dynamic Assessment of Phonological Disorders
The goal of this clinical trial is to learn about (1) how speech skills can be measured and how various tests give speech therapists different types of information for children with speech sound disorder, and (2) whether changes…
- Trial name
- NCT06075303
- Testing
- Modified Cycles
- Volunteers
- 4 people
- Sponsor
- University of Montana
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.