Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Attention Deficit Hyperactivity Disorder
Long-Term Effects of CBT on Quality of Life in Adults With ADHD
Background and objective: Although the short-term effects of cognitive behavioural therapy (CBT) in adult patients with ADHD are established, not a lot is known about longer-term effects.
- Trial name
- CBT-QoL (NCT05290311)
- Testing
- cognitive behavioural therapy
- Where
- Netherlands
- Volunteers
- 155 people
- Sponsor
- Amsterdam UMC, location VUmc
Adult ADHD
Study to Investigate the Efficacy and Tolerability of AZD1446 in Adult ADHD Patients.
The purpose of this study is to determine whether 2 weeks of treatment with AZD1446 compared to placebo improves ADHD symptoms and is well tolerated.
- Trial name
- NCT01012375
- Testing
- AZD1446
- Where
- 6 sites in United States
- Volunteers
- 135 people
- Sponsor
- AstraZeneca
Intellectual Disability
Improving Adherence Healthy Lifestyle With a Smartphone Application Based on Adults With Intellectual Disabilities
AIM: Improve adherence to physical activity in people with Intellectual disabilities with a Smartphone Application DESIGN: Randomized controlled trial SUBJECTS OF THE STUDY: People with intellectual disabilities in Occupational…
- Trial name
- APPCOID (NCT01915381)
- Testing
- multimodal intervention
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Malaga
Autism Spectrum Disorder, Anxiety
Specifying and Treating Anxiety in Autism Research
In the Specifying and Treating the Anxiety Phenotype in Autism Spectrum Disorder (STAAR) study, we conducted a16-week randomized comparative treatment trial of the Behavioral Intervention for Anxiety in Children with Autism…
- Trial name
- STAAR (NCT03279471)
- Testing
- Sertraline, CBT/BIACA
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Davis
ADHD
Caregiver Stress, Mental Health, and Self-Efficacy in ADHD Households
Investigate the relationship between caregiver stress, mental health, and self-efficacy in families with children who have ADHD.
- Trial name
- Stress (NCT06994000)
- Where
- Saudi Arabia
- Volunteers
- 160 people
- Sponsor
- Alexandria University
Autism, Food Allergies
Treatment of Autistic Children Using NAET Procedures
1. Purpose of this study is to determine whether NAET procedures are effective in the treatment of children with allergy-related autism spectrum disorders in restoring their verbal and nonverbal communication. 2.
- Trial name
- NCT00277407
- Testing
- NAET with acupressure and/or chiropractic procedures
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nambudripad's Allergy Research Foundation
Childhood Apraxia of Speech
Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in Children
This study will investigate the feasibility of applying the Rapid Syllable Transition Treatment (ReST) protocol in children with Childhood Apraxia of Speech, considering the scarcity of evidence in the context of Brazilian…
- Trial name
- ReST-SSD (NCT07636031)
- Testing
- Rapid Syllable Transition Treatment (ReST)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Aline Mara de Oliveira
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
FAB Programme for Parents of Children With NDD
The study aims to examine the effectiveness of a psychotherapy approach called Facilitator-guided Acceptance and Commitment Bibliotherapy (FAB) in improving the psychological health of parents of young children with…
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders, Intellectual Disability
- Trial name
- NCT05872737
- Testing
- Facilitator-guided Acceptance and Commitment Bibliotherapy (FAB), General Parenting Education and Advice
- Where
- 2 sites in Hong Kong
- Volunteers
- 154 people
- Sponsor
- Chinese University of Hong Kong
ADHD
Placebo-Controlled Trial With GlyTI-M Among Children With Attention Deficit Hyperactivity Disorder (ADHD)
Although psychostimulant is the first line of drug to treat Attention Deficit Hyperactivity Disorder, (ADHD), actually there are 10-20% ADHD patient do not response well to current medication.
- Trial name
- NCT01725737
- Testing
- GlyTI-M
- Where
- Taiwan
- Volunteers
- 116 people
- Sponsor
- Mackay Memorial Hospital
Attention Deficit Hyperactivity Disorder
Safety and Efficacy of GTS21 in Adults With Attention-deficit Hyperactivity Disorder
This study will be a randomized, double-blind, placebo-controlled crossover study to assess the effects of GTS21 (25 mg three times a day (tid), 75 mg tid, 150 mg tid) compared to placebo in non-smoking adults aged 18-55 with a…
- Trial name
- NCT00419445
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- CoMentis
Intellectual Disability, Multiple Congenital Anomaly
Whole Genome Sequencing in the Detection of Rare Undiagnosed Genetic Diseases in Children in China
To assess the indications and diagnostic efficiency of whole genome sequencing (WGS) in pediatric patients with unexplained intellectual disability/developmental delay, multiple congenital abnormalities and other rare and…
- Conditions
- Intellectual Disability, Multiple Congenital Anomaly, Rare Diseases
- Trial name
- NCT03424772
- Testing
- Whole genome sequencing
- Where
- 14 sites in China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Profound Mental Retardation
Radiological Examination of the Mentally Handicapped Patients
Aim of this study is to evaluate the necessity of the radiological examinations of mentally handicapped or uncooperative patients.
- Trial name
- NCT02741011
- Testing
- Radiological examination
- Volunteers
- 98 people
- Sponsor
- Tokat Gaziosmanpasa University
Autism or Autistic Traits, Family Relations
Transitioning Together Boston
A randomized controlled trial will be conducted to determine the effects of an adapted family-centered autism transition intervention called Transitioning Together/Juntos en la Transición on meaningful outcomes for families.
- Trial name
- NCT05599711
- Testing
- Transitioning Together (TT) / Juntos en la Transicion (JET), Usual autism transition care
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston Medical Center
Attention Deficit Hyperactivity Disorder
Melatonin as Adjuvant Treatment for ADHD in Adults
This study aims to evaluate the effect of melatonin supplementation as adjuvant treatment in ADHD in adults.
- Trial name
- NCT03062839
- Testing
- Melatonin 5 mg
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital Israelita Albert Einstein
Tourette Syndrome, Tic Disorders
Study of Tics in Patients With Tourette's Syndrome and Chronic Motor Tic Disorder
This study will investigate which areas of the brain are primarily involved in and responsible for tics in patients with Tourette's syndrome and chronic motor disorder.
- Trial name
- NCT00033995
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Attention Deficit Hyperactivity Disorder
A Psychosocial Treatment Program for College Students (ACCESS)
The results of this study are expected to provide important and new information regarding the treatment of academic impairment among college students with ADHD.
- Trial name
- ACCESS (NCT04186312)
- Testing
- ACCESS - Accessing Campus Connections & Empowering Student Success
- Volunteers
- 280 people
- Sponsor
- University of North Carolina, Greensboro
Transient Hypothyroxinemia of Prematurity
Neurodevelopmental Impact of Treatment in Hypothyroxinaemia of Prematurity.
Nowadays, taking care of preterm birth is associated with an important increase in survival. This increased survival comes with impairment in neurodevelopmental outcomes in long term evaluation.
- Trial name
- NEO-TYR (NCT06346236)
- Testing
- L-thyroxine at a dose of 7.5 µg/kg/d for THOP, THOP without treatment, NoTHOP
- Where
- 3 sites in France
- Volunteers
- 373 people
- Sponsor
- Hospices Civils de Lyon
Autism Spectrum Disorder
Computer-based Social Skills Training for Autism Spectrum Disorder
The primary objective of this study is to evaluate changes in subject performance on social skills assessments after engaging in a gaze-controlled video game that leverages ABA principles of learning, in comparison to an…
- Trial name
- NCT03672344
- Testing
- Lookware TM, Lookware TM Control Module
- Where
- 11 sites in United States
- Volunteers
- 54 people
- Sponsor
- BioStream Technologies, LLC
ADHD, Autism Spectrum Disorder
AWARE: Management of ADHD in Autism Spectrum Disorder
This study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents with autism.
- Trial name
- NCT05916339
- Testing
- Randomization to either Amphetamine (AMP) class of stimulant medication or Methylphenidate (MPH) class of stimulant medication, Randomization to either Alpha 2 agonist class of medication or alternate class of stimulant.
- Where
- 13 sites in United States, Canada
- Volunteers
- 500 people
- Sponsor
- Daniel Coury
Attention Deficit Hyperactivity Disorder
Towards an Understanding of the Mechanism of Action of Methylphenidate in ADHD
Approximately 1-in-20 children worldwide have Attention Deficit Hyperactivity Disorder (ADHD), a condition associated with disabling inattention, hyperactivity and impulsivity.
- Trial name
- NCT05600881
- Testing
- Methylphenidate
- Volunteers
- 35 people
- Sponsor
- University of Dublin, Trinity College
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