Clinical trials: Neurofeedback, open to volunteers
Chronic Coronary Syndrome, Anxiety Disorder
Right Dorsolateral Prefrontal Cortex Closed-loop Neurofeedback for Anxiety in High-ischaemic-risk Chronic Coronary Syndrome
This study is a prospective, randomized, sham-controlled, participant- and assessor-blinded, parallel-group clinical trial designed to evaluate the clinical efficacy, mechanistic effects, and safety of right dorsolateral…
- Conditions
- Chronic Coronary Syndrome, Anxiety Disorder, High Ischemic Risk
- Trial name
- HEART-SET-3 (NCT07543185)
- Testing
- Active right DLPFC closed-loop fNIRS-BCI neurofeedback
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Shenyang Medical College
Multiple Sclerosis
Using Motor Imagery-based Brain-computer Interface With Multiple Sclerosis Patients.
The goal of this clinical trial is to evaluate the effectiveness of a wearable brain-computer interface (BCI)-based neurofeedback system using motor imagery (MI) to support upper limb motor rehabilitation in patients with…
- Trial name
- BCI_MI_SM_2026 (NCT07472556)
- Testing
- Brain Computer Interface
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Pasquale Arpaia
ADHD
Impact of Stimulants and In-Scanner Motion on Attentive Task Performance in ADHD (ADHD_NFB)
The goal of this interventional study is to learn the effects that stimulant medication prescribed to ADHD individuals has in their performance of attentive tasks, as measured by images and data collected through neuroimaging…
- Trial name
- ADHD_NFB (NCT06779825)
- Testing
- fMRI Neurofeedback attention task
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Children's Hospital
Mild Traumatic Brain Injury, Photophobia
Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury
The goal of this study is to complete a pilot study testing the feasibility and acceptability of low-intensity pulse-based transcranial stimulation (LIP-tES) neurofeedback intervention for reducing photosensitivity symptoms in…
- Trial name
- NCT06109909
- Testing
- Micro Current Neurofeedback Device using Low-Frequency Pulse-Based Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Stroke, Brain Computer Interface
Evaluation of an Adaptive Neurotechnology Based on Motor Imagery in Patients Who Suffered a Left Hemisphere Stroke
This randomized clinical trial will evaluate the feasibility and performance of a co-adaptive motor imagery brain-computer interface (BCI) for upper-limb rehabilitation in adults with subacute left-hemisphere stroke.
- Conditions
- Stroke, Brain Computer Interface, Motor Imagery, Neurofeedback
- Trial name
- NCT07875257
- Testing
- BCI sessions with neurofeedback, BCI sessions without neurofeedback
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
Tinnitus, Subjective
Advanced Neurofeedback for Tinnitus
This study investigates neurofeedback as a potential treatment for chronic tinnitus. Neurofeedback is a non-invasive method that aims to regulate brain activity and may help reduce tinnitus symptoms and the distress associated…
- Trial name
- ANTARES (NCT07830069)
- Testing
- Neurofeedback
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Depression - Major Depressive Disorder
Effect of Neurofeedback and TMS
The goal of this clinical trial is to is to learn whether adding EEG neurofeedback (NFB) to repetitive transcranial magnetic stimulation (rTMS) is safe and feasible for adults with major depressive disorder (MDD).
- Trial name
- NCT07892287
- Testing
- Repetitive Transcranial Magnetic Stimulation, Alpha-down EEG Neurofeedback
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Inflammatory Bowel Diseases
REgulating Pain Through Neurofeedback in infLammatory Bowel diseasE and Musculoskeletal Dysfunction
Clinical trial with a CE-marked medical device. Use as indicated in patients with chronic inflammatory bowel disease and musculoskeletal pain.
- Trial name
- RELIEF (NCT07473076)
- Testing
- Experimental group
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Well-Being, Psychological, Mood Disturbance
Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms
The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a…
- Conditions
- Well-Being, Psychological, Mood Disturbance, Emotional Regulation, Dissociation
- Trial name
- NCT07217925
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Psychosis; Schizophrenia-Like, Healthy Controls
Mechanisms of Response to Therapeutic Intervention in Clinical High Risk (CHR) for Psychosis
This study, "Psychobiological Follow-up Study of Transition from Prodrome to Early Psychosis", will be conducted in collaboration with the Shanghai Mental Health Center (SMHC) and several data processing sites in the United…
- Trial name
- NCT06542640
- Testing
- Mb-rt-fMRI-NFB, rTMS
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Knee Osteoarthritis
Neurofeedback for Pain Sensitization in Knee Osteoarthritis
The goal of this clinical trial is to learn whether a training method called neurofeedback is safe and practical to use in people with knee osteoarthritis (knee OA).
- Trial name
- NCT07832682
- Testing
- FWR Down-Conditioning Neurofeedback
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Borderline Personality Disorder
Brain Signal Training to Enhance Affect Down-regulation
Individuals with Borderline Personality Disorder (BPD) experience intensive, instable negative emotions. Hyperactivity of the amygdala is assumed to drive exaggerated emotional responses in BPD.
- Trial name
- BrainSTEADy (NCT06626789)
- Testing
- Amygdala neurofeedback
- Where
- 6 sites in Germany
- Volunteers
- 164 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Schizophrenia, Schizoaffective
Frontal Gamma Coherence Neurofeedback for Patients With Schizophrenia
This preliminary, randomized, double-blind, placebo-controlled clinical trial will evaluate frontal gamma coherence neurofeedback in adults with schizophrenia.
- Trial name
- NCT07659938
- Testing
- Frontal gamma coherence neurofeedback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- BioSignal Solutions LLC
Attention Deficit Disorder With Hyperactivity, Executive Function Disorder
Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children.
A multi-center, randomized controlled trial is being conducted to investigate the efficacy of a novel digital therapeutics (DTx) program that utilizes a cross-training approach between neurofeedback training and executive…
- Trial name
- ADHD (NCT06369714)
- Testing
- Concerta, Digital therapeutics
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Lei Lei, MD
Stroke, Cognitive Impairment
Training Cognition With Neurofeedback After Stroke
Post-stroke cognitive impairment (PSCI) is a common source of invisible disability. The actual techniques of cognitive remediation have been reported to have only a small effect, justifying the need to foster research in this…
- Trial name
- CITRINeS (NCT06852209)
- Testing
- Cognitive remediation therapy, Neuropsychological assessment, Real-time functional MRI neurofeedack (rt-fMRI NF)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Adults With Variability in Their Mood
Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)
Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day
- Trial name
- BandR (NCT07252011)
- Testing
- Transcranial alternating current stimulation (tACS), Neuro/biofeedback, Recall
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy
Individual Differences in Cognitive Control Predict Real-time fMRI Neurofeedback Performance
The goal of this study is to investgate whether individual differences of cognitive control capacity could predict neurofeedback performance and the behavioral effects resulting from successful anterior insula regulation via…
- Trial name
- NCT07211269
- Testing
- Real-time fMRI neurofeedback training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Nonsuicidal Self Injury, Emotion Regulation
Neuro- and Biofeedback in Nonsuicidal Self-injury
Nonsuicidal self-injury (NSSI) is defined as the direct, deliberate destruction of one's own body tissue without suicidal intent, typically including behaviors such as cutting, burning, or hitting oneself.
- Trial name
- NCT05656001
- Testing
- Real-time functional magnetic resonance imaging Neurofeedback and Real-time Biofeedback
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Östergötland
Anxiety Disorders
Functional Near-infrared Spectroscopy for Anxiety Monitoring and Neurofeedback.
The objective of this subproject is to validate the efficacy of the fNIRS real-time anxiety monitoring and neurofeedback system.
- Trial name
- NCT05921773
- Testing
- AI-fNIRS neurofeedback device
- Where
- Taiwan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Schizophrenia, Auditory Hallucination
Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication…
- Conditions
- Schizophrenia, Auditory Hallucination, Treatment-resistant Schizophrenia
- Trial name
- NCT05299749
- Testing
- stg-rt-fMRI-Neurofeeback
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Boston VA Research Institute, Inc.