Clinical trials: Neurogenic Bowel Dysfunction
Spinal Cord Injuries, Constipation
Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI
To measure a baseline for each subject, an abdominal x-ray (KUB) was performed, the SCI Bowel Survey and Treatment Satisfaction Questionnaire (TSQM) were administered and the subject's weight determined.
- Conditions
- Spinal Cord Injuries, Constipation, Neurogenic Bowel
- Trial name
- TWBC (NCT04671030)
- Testing
- Neostigmine and Glycopyrrolate, Iontophoresis
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Injuries, Spinal Cord, Neurogenic Bowel
Evaluation of a Bowel and Bladder Health Management Program for Individuals With Spinal Cord Injury (SCI)
This study will look at the use of a telehealth version of a self management program in individuals with both new onset and chronic traumatic spinal cord injuries. The program is called Health Mechanics.
- Conditions
- Injuries, Spinal Cord, Neurogenic Bowel, Urinary Bladder, Neurogenic
- Trial name
- NCT01920243
- Testing
- Health Mechanics Program
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Michigan
Spinal Cord Injuries, Neuromodulation
Improving Pelvic Rehabilitation Using Epidural Stimulation After Spinal Cord Injury
The investigators will recruit up to 20 volunteers with chronic, supra-sacral SCI. Following screening, eligible participants will enter 'Phase I', they will complete baseline outcome measures and then have the epidural spinal…
- Conditions
- Spinal Cord Injuries, Neuromodulation, Neurogenic Bladder, Neurogenic Bowel
- Trial name
- ImPRESS (NCT06515223)
- Testing
- Epidural Spinal Cord Stimulation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University College, London
Perineum; Tear, Traumatic, Anal Tear
Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results
French multicentric retrospective cohort study including patients who underwent an ano-perineal trauma following a personal watercraft/jet-ski accident and that were treated in France from January 2017 to December 2023.
- Conditions
- Perineum; Tear, Traumatic, Anal Tear, Anal Incontinence
- Trial name
- TP-JET (NCT06368284)
- Testing
- Patients who experienced an ano-perineal trauma following a PWC/Jet-Ski accident
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Neurogenic Bowel (Disorder), Fecal Constipation
Comparing Transanal Irrigation With Navina Smart vs. Standard Bowel Care in Patients With Multiple Sclerosis
A randomized, superiority, controlled, interventional, prospective, multicentre, post-market study of TAI with Navina™ Smart versus Standard Bowel Care performed in a population of 92 subjects suffering from Multiple Sclerosis…
- Conditions
- Neurogenic Bowel (Disorder), Fecal Constipation, Fecal Incontinence, Multiple Sclerosis
- Trial name
- NCT04707976
- Testing
- Navina Smart, Standard Bowel Care
- Where
- 9 sites in Denmark, France and 4 more
- Volunteers
- 92 people
- Sponsor
- Wellspect HealthCare
Urinary Bladder, Neurogenic, Blood Pressure
Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
This study will incorporate critical cross viscero-visceral intersystem interactions to 1) investigate in a controlled laboratory setting and then with mobile at-home monitoring the extent, severity, and frequency of occurrence…
- Conditions
- Urinary Bladder, Neurogenic, Blood Pressure, Autonomic Dysreflexia, Bowel Incontinence
- Trial name
- NCT04193709
- Testing
- Spinal Cord Epidural Stimulation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Louisville
Spinal Cord Injuries, Neurogenic Bowel
Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury
Assessing the sacral nerves is an integral aspect of the evaluation after a spinal cord injury. Being located at the lower end of the spinal cord, the sacral nerves reflect how signals travel through the injured spinal cord.
- Conditions
- Spinal Cord Injuries, Neurogenic Bowel, Neurogenic Bladder Dysfunction
- Trial name
- NCT06333886
- Testing
- Sacral electromyography
- Where
- Canada
- Volunteers
- 450 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis
Sacral Neuromodulation for Neurogenic Lower Urinary Tract, Bowel and Sexual Dysfunction
A multi-center double-blinded placebo-controlled randomized clinical trial. The patients will be randomized into two groups. To investigate the efficacy of SNM to improve the key bladder diary variables compared to placebo (i.e.
- Conditions
- Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis, Sacral Neuromodulation, Bowel Dysfunction
- Trial name
- NCT05380856
- Testing
- Turning ON the neuromodulator, Turning OFF the neuromodulator
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Neurogenic Bowel
An Open, Qualitative, Prospective, Multicenter Trial of a Novel Transanal Irrigation System in Spinal Cord Injured Patients.
This study is designed as an open, prospective, non-controlled, qualitative, multicentre study of a novel transanal irrigation system performed in a population of 150 subjects suffering from spinal cord injury and confirmed…
- Trial name
- NCT02979808
- Testing
- Navina Smart
- Where
- 11 sites in Denmark, France and 6 more
- Volunteers
- 150 people
- Sponsor
- Dentsply International
Spinal Cord Injuries, Neurogenic Bowel
Exoskeleton Neurogenic Bowel Dysfunction Study
The purpose of the study is to assess the effects of exoskeleton training on neurogenic bowel disorders in spinal cord injury/ disease.
- Trial name
- NCT05176327
- Testing
- Exoskeleton training with Ekso NR
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong